Jonathan Godbout Representative Publications

Godbout, J.P., Chen, J., Abraham, J., Richwine, A.R., Berg, B.M., Kelley, K.W., and Johnson, R.W. (in press) Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system. FASEB Journal

Berg, B.M., Godbout, J.P., Chen, J., Kelley, K.W., and Johnson, R.W. (in press) a-Tocopherol and selenium facilitate recovery from lipopolysaccharide-induced sickness behavior in aged mice. Journal of Nutrition

Richwine, A.R., Godbout, J.P, Chen, J., Berg, B.M., Escobar, J., Millard, D.K., and. Johnson, R.W. (in press) Improved psychomotor performance in aged mice fed diet high in antioxidants is associated with reduced ex vivo interleukin-6 production. Brain, Behavior, and Immunity.

Godbout, J.P., Berg, B.M., Kelley, K.W., and Johnson, R.W. (2004) a-Tocopherol reduces lipopolysaccharide-induced peroxide radical accumulation and interleukin-6 secretion in primary murine microglia and in brain. Journal of Neuroimmunology. 149, 101-109.

Godbout, J.P. and Johnson, R.W. (2004) Review: Interleukin-6 in the Aging Brain. Journal of Neuroimmunology. 147, 141-144.

Berg, B.M., Godbout, J.P., Kelley, K.W., and Johnson, R.W. (2004) a-Tocopherol attenuates lipopolysaccharide-induced sickness behavior in mice. Brain, Behavior, and Immunity. 18, 149-157.

Hartman, M.E., O’Connor J.C., Godbout, J.P., Minor, K.D., Mazzocco, V.R. and Freund, G.G. (2004) Insulin Receptor Substrate-2-Dependent Interleukin-4 Signaling in Macrophages is Impaired in Two Models of Type 2 Diabetes Mellitus. Journal of Biological Chemistry. 279: 28045-28050.

Godbout, J.P., Pesavento, J., Hartman, M.E., Manson, S.R., and Freund, G.G. (2002) Methylglyoxal Enhances Cisplatin-Induced Cytotoxicity By Activating PKCd _. Journal of Biological Chemistry. 277: 2554-2561.

Godbout, J.P., Cengel, K.A., Cheng, S., Minshall, C., Kelley, K.W., and Freund, G.G. (1999) Insulin activates caspase-3 by a phosphatidylinositol 3’-kinase dependent pathway. Cellular Signalling. 11: 15-23.

Cengel, K.A., Godbout, J.P., and Freund, G.G. (1998) Phophatidylinositol 3’-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase. Biochemical and Biophysical Research Communications. 242: 513-517.