Daren L. Knoell, PhD

Associate Professor of Pharmacy Practice and Internal Medicine

Davis Heart and Lung Research Institute
473 W. 12th Ave., Room 405A
Columbus, OH 43210

Office: (614) 292-0075

Fax: (614) 292-1335

daren.knoell@osumc.edu

Education

• Pharm.D. 1989, University of Nebraska, Omaha NE
• Clinical Residency 1990, University of California at San Francisco
• Post-Doctoral Fellowship 1993, University of California at San Francisco

Areas of Interest

• Lung Inflammation and Remodeling
• Lung Epithelial Cell Biology
• Metal Homeostasis

My laboratory investigates lung epithelial cell behavior during normal cell function, wound remodeling, and disease pathogenesis. Our investigations are translational and utilize primary human lung cultures, animal models, and humans subjects.  We primarily focus our attention on the identification of key molecular targets in the lung that promote inappropriate lung cell function. We then interrogate these targets to better understand disease predisposition and pathogenesis. The overarching goal of these studies is to develop innovative therapeutic strategies to prevent or treat lung disease.

Biography

Daren Knoell, PharmD, F.C.C.P., is an Associate Professor in the College of Pharmacy. He also holds joint appointments as a member of the Division of Pulmonary and Critical Care Medicine, Center for Microbial Interface Biology, Center of Excellence in Pharmacogenomics, Dorothy M. Davis Heart and Lung Reseach Institute Lung, and Department of Medical Pharmacology. Dr. Knoell's research is supported by the National Institutes of Health.

Dr. Knoell has received recognition for his scholarship and service in pulmonary medicine. He was a recipient of the Merck & Co Award for Outstanding Achievement in Pulmonary Biology 2004 as well as a recipient of the American College of Clinical Pharmacy Career Development Award 2004. He was honored as a "Fellow" in the American College of Clinical Pharmacy, served as a member of the American Lung Association of Ohio Board of Directors, and currently serves as a member of the National Institutes of Health Asthma Clinical Research Network II (ACRNII) Expert Review Panel as well as the FDA Pulmonary and Allergy Drug Advisory Committee (PADAC). He received his doctorate degree in pharmacy from the University of Nebraska College of Pharmacy followed by completion of a clinical residency at the University of California at San Francisco. Dr. Knoell then completed a research fellowship at UCSF in the laboratory of Dr. Francis Szoka before coming to The Ohio State University.

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