The Ohio State University
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Center for Stress & Wound Healing
- Center for Stress & Wound Healing - A Designated National Institutes of Health Mind-Body Research Center
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- Research Projects
- Researchers
 
National Institutes of Health
 
 
Support Cores
 
General Clinical Research Center
 
Training Program
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- Dr. Phillip Marucha - Dr. Marucha
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Associate Professor, Dept. of Periodontology

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Research Interests
Molecular regulation of cytokine gene expression in human peripheral blood polymorphonuclear leukocytes; Expression of protein inflammatory mediators in neutrophils activated by chemotactic factors and other inflammatory mediators; Stress-induced modulation of periodontitis in the rat; Protein mediator expression on models of bacterial disease; Neuroendocrine modulation of wound healing in human and animal models.

 

Publications

Kiecolt-Glaser, J., Marucha, P.T., Malarkey, W., Mercado, A. and Glaser, R. " Slowing of wound healing by psychological stress." Lancet, 1995, 346:1194-1196.

Fernandez, M.C., Walters, J.D., and Marucha, P.T. "Transcriptional and post:transcriptional regulation of IL-1b mRNA expression induced by GM-CSF in PMN." Journal of Leukocyte Biology 59: 598-603, 1996.

Walters, J.D., Cario, AC, Danne, MM, Marucha PT. "An inhibitor of ornithine decarboxylase antagonizes human polymorphonuclear leukocyte priming in vitro." Journal of Inflammation 48:40-46, 1998

Padgett, DA, Marucha, PT, and Sheridan, JF. "Neuroendocrine effects on wound healing in SKH-1 feamle mice." Brain, Behavior, and Immunity 12: 64-73, 1998.

Marucha, PT, Kiecolt-Glaser, JK, and Favagehi, M. " Mucosal wound healing is impaired by examination stress." Psychosomatic Medicine 60:362-365, 1998.

Fernandez, MC, Marucha, P, Rojas, IG, and Walters, JD "The role of protein kinase C and calcium in induction of human polymorphonuclear leukocyte IL-1b gene expression by GM-CSF." Cytokine (accepted 7/99)

Kiecolt-Glaser, JK, Page, GG, Marucha, PT, MacCallum, RC, Glaser, R. Psychological influences on surgical recovery: Perspectives from psychneuroimmunology." American Psychologist 53:1209-18, 1998.

Rozlog, L.A., Kiecolt-Glaser, J.K., Marucha, P.T., Sheridan, J.F., Glaser, R. "Stress and Immunity: Implications for viral disease and wound healing". J. Perio. 70:786-792. 1999.

Glaser, R., Kiecolt-Glaser, JK, Marucha, PT, MacCallum, RC, Laskowski, BF, Malarkey, W., "Stress-related changes in pro-inflammatory cytokine production in wounds". Arch. Gen. Psych. 56: 450-456, 1999.

Marucha, P.T., Sheridan, J.F., Padgett, D.A. "Stress and Wound Healing." In Ader, B., Felten, D., Cohen, N. eds. Psychoneuroimmunology, 3rd ed., Vol.2. New York, Academic Press, 2000.

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