Robertson, Fredrika M.

Fredika M. Robertson, Ph.D.

Professor
Department of Molecular Virology, Immunology, and Medical Genetics

Joint Appointments
Departments of Surgery and Internal Medicine

Contact Information:

Laboratory:
2063B & E Graves Hall
333West 10th Ave.
Columbus, Oh. 43210
Ph. (614) 292-6947

Research Interests:
Role of growth factors, adhesion molecules, and reactive intermediates in wound healing, skin carcinogenesis, and breast cancer.

Selected Publications:
Robertson, F.M., Parrett, M.L., Joarder, F.S., Ross, M.S., Abou-Issa, H.Alshafie, G. and Harris, R.E. 1998. Ibuprofen-Induced Inhibition of Cyclooxygenase Isoform Gene Expression and Regression of Rat Mammary Carcinomas. Cancer Letts 122:165-175.

Oberyszyn, T.M., Conti, C.J., Ross, M.S., Oberyzsyn, A.S., Tober, K.L., Rackoff, A.I. and Robertson, FM. 1998. b2 Integrin/ICAM-1 Adhesion Molecule Interactions in Cutaneous Inflammation and Tumor Promotion. Carcinogenesis 19:(3) 101-111.

Oberyszyn T.M., Ross, M.S., Tober, K.L. and Robertson, F.M. 1998. Inhibitory effects of Pentoxifylline on ultraviolet B light induced cutaneous inflammation. Molec. Carcinogenesis 22:16-25.

Snapka, R.M., Ge, S., Trask, O.J., and Robertson, F.M. 1998. Unbalanced growth in mouse cells with amplified dhfr genes. Cell Proliferation, 30: 385-399.

Tober, K.L., Cannon, R.E., Spalding, J.W., Oberyszyn, T.M., Parrett, M.L., Rackoff, A.I., Oberyszyn, A.S., Tennant, R.W., and Robertson, F.M. 1998. Comparative Expression of Novel Vascular Endothelial Growth Factor/Vascular Permeability Factor Transcripts In Skin, Papillomas and Carcinomas of v-Ha-ras Tg.AC Transgenic Mice and FVB/N Mice. Biochem. Biophys. Res. Commun. 247:644-653.

Brueggemeier, R.W., Quinn, A.L., Parrett, M.L., Joarder, F.S., Harris, R.E., and Robertson, F.M. 1999 Correlation of Aromatase and Cyclooxygenase Gene Expression in Human Breast Cancer Specimens. Cancer Letts. 140:27-35.

Harris, R.E., Robertson, F.M., Abou-Issa. H.M., Farrar, W.B. and Brueggemeier, R.W. 1999. Genetic Induction and Upregulation of Cyclooxygenase (COX) and Aromatase (CYP19): An Extension of The Dietary Fat Hypothesis of Breast Cancer. Medical Hypotheses 52:291-292.

Alshafie, G.A., Harris, R.E., Robertson, F.M., Parrett, M.L., Ross, M.S., and Abou-Issa, H. 1999. Chemopreventive Effects of Ibuprofen and N-(4-hydroxyphenyl)retinamide in a Rat Mammary Tumor Model. Anti-Cancer Research, 19:1-6.

Parrett, M.L., Abou-Issa, H.M., Alshafie, G., Ross, M.S., Harris, R.E., Robertson, F.M. 1999. Comparative Ability of Ibuprofen and N-(4-Hydroxyphenyl)retinamide to Inhibit Development of Rat Mammary Adenocarcinomas Associated With Differential Inhibition of Gene Expression of Cyclooxygenase Isoforms. Anti-Cancer Res. 19:6-10.