Bresler, Herbert
Herbert Bresler, Ph.D.
Technology Director, Healthcare Products at Battelle
Joint Appointment:
Department of Molecular Virology, Immunology and Medical Genetics
Contact Information:
Battelle Health & Life Sciences
505 King Ave.
Columbus, OH 43201
breslerh@battelle.org
(614) 424-7129
FAX 458-7129
Research Interests:
Dr. Bresler has over 15 years of professional experience in diagnostic immunology and biological therapy development. As Technology Director for Health & Life Sciences at Battelle, he has primary responsibility for strategic technology focus, technical due diligence, and for coordinating outside research collaborations. He evaluates new technology-based business opportunities and advises research programs in immunology, infectious diseases, and oncology. In addition to his role as Technology Director, he has a lead technical or advisory role in several programs at Battelle developing complex biotechnology devices, and tissue engineering products. His own research interests include immunotherapy of cancer, cellular therapies, tissue engineering, autoimmune disease and disease biomarkers.
Selected Publications:
Kim JA, Bresler HS, Martin, EW, Aldrich, W, Heffelfinger M, Li X and Triozzi PL. Cellular Immunotherapy for Patients with Metastatic Colorectal Carcinoma Using Lymph Node Lymphocytes Localized In Vivo by Radiolabeled Monoclonal Antibody. Cancer 86(1):22-30, July 1999.
Rucker R, Bresler HS, Heffelfinger M, Kim J, Martin E, and Triozzi PL. Low-dose Monoclonal Antibody CC49 Administered Sequentially with Granulocyte-Macrophage Colony Stimulating Factor in Patients with Metastatic Colorectal Cancer. Journal of Immunotherapy 22(1):80-84, January 1999.
Triozzi PL, Aldrich WA, Bresler HS, Para MF and Flancbaum LJ. Cellular Immunotherapy of Advanced Human Immunodeficiency Virus Type 1 Infection Using Autologous Lymph Node Lymphocytes: Effects on Chemokine Production. Journal of Infectious Diseases 179:245-248, January 1999.
Saboori AM, Rose NR, Bresler HS, Vladut-Talor M, Burek CL. Iodination of human thyroglobulin (Tg) alters its immunoreactivity. I. Iodination alters multiple epitopes of human Tg. Clinical and Experimental Immunology 113(2):297-302, August 1998.
Triozzi PL, Bresler HS, and Aldrich WA. HIV-1-Reactive Chemokine Producing CD8+ and CD4+ Cells Expanded from Infected Lymph Nodes. AIDS Research and Human Retroviruses 14(8):643-649, May 1998.
Saboori AM, Burek CL, Rose NR, Bresler HS, Talor M, Kuppers RC. Tryptic peptides of human thyroglobulin: I. Immunoreactivity with murine monoclonal antibodies. Clinical and Experimental Immunology 98(3):454-458, December 1994.
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