David Schonberg

Integrated Biomedical Science Graduate Program (IBGP)

Dr Dana McTigue Lab

B.A. in Zoology, Miami University
M.PH. in Public Health, The Ohio State University

Thesis Advisor:  Dana M. McTigue

Phone:  (614) 644-4711
Fax:  (614) 688-8742
E-Mail:  schonberg.2@osu.edu

Research Area: 

My research focuses on how inflammation can lead to new oligodendrocyte formation following spinal cord injury.  To uncover the mechanism or factors necessary to induce oligogenesis after injury I will begin with utilizing simplified models such as in vivio microinjections followed by supporting my hypotheses using knockout mice and/or siRNA and in vitro systems.  Since last year I have shown that there is a particular inflammatory paradigm that results in new oligogenesis and now I am beginning to study specific elements involved in this process which range from cytokines and growth factors to transition metals.

Presentations at National Meetings:

Schonberg DL, Popovich PG and McTigue DM.  Distinct intraspinal macrophage activation protocols differentially influence oligodendrocyte genesis.  Institute for Behavioral Medicine Research Conference (Columbus, OH) 2007.