Clinical faculty
Research faculty
Research Coordinator
- Barbara Landolfi
Phone: 614-293-8760
Now Recruiting!
Corneal crosslinking for keratoconus Richard Keates, M.D. (PI)
Corneal crosslinking is a non-invasive (non-penetrating) procedure that increases collagen which is a natural anchor in the cornea (the front clear portion of the eye). This study will help determine if crosslinking halts the progression of keratoconus (a progressive disease that involves the thinning of the cornea) through the use of vitamin B2 drops and ultraviolet light.
You can contact Richard Keates, M.D. at richard.keates@osumc.edu with questions.Corneal crosslinking in ectasia after refractive surgery Richard Keates, M.D. (PI)
This study will determine if vitamin B2 and ultaviolet light will halt the progression of ectasia(a progressive thinning of the cornea that sometimes follows refractive surgery, such as LASIK or PRK.)
You can contact Richard Keates, M.D. at richard.keates@osumc.edu with questions.
Rates and risk factors for fungal keratitis among contact lens wearers Thomas Mauger, M.D. (PI), Richard Lembach, M.D., and Reynell Harder-Smith, D.O.Recent reports suggest that there has been an increase in fungal keratitis amongst contact lens wearer. The CDC is conducting an ongoing investigation into whether this increase is related to contact lens solutions which have been recently pulled from the market. This study will determine if there is a link between contact lens wear and eye infections. It will also identify behavioral and environmental risk factors with a retrospective review of past cases of fungal keratitis.
You can contact Barbara Landolfi at 614-293-8760 with questions.
DYME: A double-masked, randomized study of the safety and effectiveness of DYME as an agent for selective staining of the anterior capsule during cataract surgery Thomas Mauger, M.D. (PI), Richard Lembach, M.D., Dave Castellano, M.D., and Reynell Harder-Smith, D.O.
Studies have shown that using a dye during cataract surgery makes the surgery easier and the outcome better especially if the patient has a certain kind of cataract. This study analyzes whether the dye, DYME, will aid the surgeon when performing cataract surgery.
If you have a cataract and are interested in determining whether you are a candidate for this study, contact Barbara Landolfi at 614-293-8760.
Current Clinical Trials
RH Keates (PI), Corneal crosslinking for keratoconus, University Funded, 2008-10.
RH Keates (PI), Corneal crosslinking in ectasia after refractive surgery, University Funded, 2008-10.
TF Mauger (PI), RG Lembach, D Castellano, R Harder-Smith. A double-masked randomized study of the
safety and effectiveness of DYME as an agent for selective staining of the
anterior capsule during cataract surgery, Aqumen Biopharmaceuticals, N.A., Inc.
2007-08.TF Mauger (PI), RG Lembach, ME Dangel, R Harder-Smith. Rates and risk factors for fungal keratitis
among contact lens wearers, John Hopkins University, 2006-08.
FW Price (PI), TF Mauger. Clinical investigation of OPHTEC iris reconstruction lens model 311,
OPHTEC USA, Inc., June 2007
Completed Clinical Trials
D Grzybowski, C Roberts, AM Mahmoud, S Chang. “Model for Non-Ectatic Increase in the Posterior Corneal
Elevation after an Ablative Procedure,” Invited Paper to Cataract &
Refractive Surgery, 31(1) 72-81, 2005.
RG Lembach (PI),
TF Mauger, C Roberts. Evaluation of the utility of intra-operative topography
to optimize corneal shape during penetrating keratoplasty, BIOMEC, 2004-07.
TF Mauger (PI), RG Lembach, ME Dangel A study to evaluate the clinical and microbial efficacy
of 0.6% ISV-403 compared to vehicle in the treatment of bacterial
conjunctivitis, Bausch and Lomb, 2006-07.
Study to
evaluate the clinical and microbial efficacy of 0.6% ISV-403 compared
to vehicle in the treatment of bacterial conjunctivitis
Evaluation of the utility of intra-operative topography to optimize corneal shape during penetrating keratoplasty
