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Glen Apseloff, M.D., F.C.P.Director of Clinical Trials
Research Professor
Department of Pharmacology
5086 Graves Hall
333 W. 10th Avenue
Columbus, OH 43210
Phone: (614) 292-8190
Email: apseloff.1@osu.edu
Research InterestsPhase I and II Clinical Trials, Efficacy of gallium nitrate in the treatment of autoimmune disorders
Clinical PharmacologyThe Division of Clinical Trials is a fully self-sufficient drug development program which provides a variety of services to the department, including teaching and conducting clinical research. The Division has been conducting clinical trials since 1977 and has investigated a wider range of medications. The research is sponsored by pharmaceutical corporations and is undertaken in a free-standing 39-bed facility staffed by qualified physicians.
Basic ScienceResidual funds from the Division of Clinical Trials have supported a variety of basic science research projects, many of them involving the effects of gallium nitrate on autoimmune diseases in animal models. This research has resulted in three use patents. Some studies are ongoing, including an investigation into the distribution and elimination of gallium in mice.
Program AffiliationsOhio State University Division of Clinical Trials
http://www.medicine.osu.edu/clinicalpharm
EducationM.D., The Ohio State University, College of Medicine. 1986.
Publications
HIV Testing in early clinical trials. Apseloff, G. (2002) Clin. Pharacol. 42: 601-604.
Practical considerations regarding the influence of the menstrual cycle of leukocyte parameters in clinical trials.. G. Apseloff, B. Xiaohui, L. LaBoy-Goral, H. Friedman and A. Shah (2000) ) Am. J. Therap. 7: 297-302.
The effects of ziprasidone on steady-state lithium levels and renal clearance of lithium.. G. Apseloff, D. Mullet, K.D. Wilner, R.J. Anziano, T.G. Tensfeldt, S.M. Pelletier and N. Gerber (2000) Br. J. Clin. Pharmacol 49(S1): 61-64.
Ziprasidone and the activity of cytochrome P450 2D6 in healthy extensive metabolizers.. K.D. Wilner, S.B. Demattos, R.J. Anziano, G. Apseloff and N. Gerber (2000) Br. J. Clin. Pharmacol 49(S1): 43-47. Therapeutic uses of gallium nitrate - past, present, and future. G. Apseloff (1999) Am. J. Therap 6: 327-339.
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