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Joseph Kitzmiller, MD, PhD, FCP

Joseph Kitzmiller, M.D., Ph.D.

Positions:

NIH Translational Scholar in Pharmacogenomics Link​

Assistant Professor

College of Medicine, Department of Pharmacology                                    

College of Engineering, Department of Biomedical Engineering

Associate Director
OSUWMC Center For Pharmacogenomics Link

Director

OSU Fellowship Training Program in Clinical Pharmacology & Pharmacogenomics Link
 
Office:
5086 Graves Hall, 333 W. 10th Avenue

Columbus, OH  43210
Phone: (614) 292-8438
Fax: (614) 292-7232

joseph.kitzmiller@osumc.edu​

Kitzmiller BioSketch July 2015.pdf


Education:

MS, PhD - College of Engineering, The Ohio State University
MD - College of Medicine, The Ohio State University
Internship - Internal Medicine, The Ohio State University
Fellowship - Clinical Pharmacology, The Ohio State University

Research Interests & Extramural Funding:

Translational Medicine, Pharmacogenomics, Pharmacoanalytic Methodology, Clinical Pharmacology, Research Ethics, and Drug Development; Cardiology, Pain and Psychology-related Pharmacology.

National Institutes of Health - Statin Pharmacogenomics. Career Development K23 Award (2011-2016)

American Heart Association - Racial disparities in heart failure clinical outcomes: discovery of genetic markers for high-risk African-Americans (2014-2016)

Advancing a Healthier Wisconsin - Modulating Inflammation (2012) 


Recent Publications

Kitzmiller JP, Talameh JA, Isackson PJ, Changxing MA, Medina MW, Dauki AM, Mikulik EB, Ochs-Balcom HM, Vladutiu GD. GATM polymorphism associated with the risk for statin-induced myopathy not replicated in case-control analysis of 715 dyslipidemic individuals. Cell Metabolism 2015; 21(4):622-7.​

Luzum JA, Theusch E, Taylor KD, Wang A, Sadee W, Binkley PF, Krauss RM, Medina MW, Kitzmiller JP. Individual and combined associations of genetic variants in CYP3A4, CYP3A5, and SLCO1B1 with simvastatin and simvastatin acid plasma concentrations. Journal of Cardiovascular Pharmacology 2015; In Press

Kitzmiller JP, Barnett CJ, Steiner NS, Stoicea N, Kamar N, Luzum JA, Mikulik E, Bergese SD. Buprenorphine: Revisiting the Efficacy of Transdermal Delivery System. Therapeutic Delivery 2015; 6(4):419-22.

Wang J, Talameh JA, Phelps MA, Kitzmiller JP. A liquid chromatography-tandem mass spectrometry assay for the simultaneous quantificati​on of simvastatin, lovastatin, atorvastatin, and their major metabolites in human plasma. Journal of Chromatography B 2015; 984:18–25.

Kitzmiller JP, Talameh JA, Baldassarre D, Krauss RM, Medina MLW. CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the Cholesterol and Pharmacogenetics study cohort. Pharmacogenetics and Genomics 2014; 24(10):486-591.

Talameh JT, Kitzmiller JP. Pharmacogenetics of Statin-Induced Myopathy: A focused review of the clinical translation of pharmacokinetic genetic variants. Pharmacogenomics and Pharmacoproteomics 2014; 5:2-10.

Korbel L, George M, Kitzmiller JP. Clinically-Relevant Pharmacogenomic Testing in Pediatric Practice. Clinical Pediatrics 2014; 53:831-8.

Kitzmiller JP, Phelps MA, Neidecker MV, Apseloff G. Establishing a clinical pharmacology fellowship program for physicians, pharmacists, and pharmacologists: a newly-accredited interdisciplinary training program at the Ohio State University. Advances in Medical Education and Practice 2014; 5;191-6.

Sardo CL, Kitzmiller JP, Apseloff G, Harris RB, Roe DJ, Stoner GD, and ET Jacobs. An open-label, randomized crossover trial of lyophilized black raspberries on postprandial inflammation in older, obese males. American Journal of Therapeutics ​2013; August 26 EPub ahead of print.

George M, Haasz M, Coronado A, Salhanick S, Korbel L, Kitzmiller JP. Acute dyskinesia, myoclonus, and akathisa in an adolescent male abusing quetiapine via nasal insufflations: a case study. BMC Pediatrics 2013; 13:187.

Kitzmiller JP, Binkley PF, Pandey Sr, Suhy AM, Baldassarre D, Hartmann K. Statin pharmacogenomics: Pursuing biomarkers for predicting clinical outcomes. Discovery Medicine 2013; 16(86) 45-53.

Kitzmiller JP, Foraker RE, Rose KM. Lipid-lowering pharmacotherapy and socioeconomic status: Atherosclerosis risk in communities (ARIC) surveillance study. BMC Public Health 2013; 13:488.

Apseloff G, Kitzmiller JP, Tishler CL. Credibility and comprehension of healthy volunteers in lengthy inpatient drug studies.  American Journal of Therapeutics 2013; 20(3):257-260.

Baldassarre D, Amato M, Frigerio B, Columbo G, Binkley PF, Pandey SR, Suhy AM, Hartmann K, Kitzmiller JP. Pharmacogenomic biomarkers for the prediction of statins efficacy and safety. Arteriosclerosi 2013; 4:23-35.

Kitzmiller JP, Sullivan DM, Phelps MA, Wang D, Sadee W. CYP3A4/5 combined genotype analysis for predicting statin Dose requirement for optimal lipid control.  Drug Metabolism & Drug Interaction 2013; 28(1):59-63.

Kapil RP, Cipriano A, Friedman K, Michels G, Shet MS, Colucci SV, Apseloff G, Kitzmiller JP, Harris SC. Once-weekly transdermal buprenorphine application results in sustained and consistent steady-state plasma levels. Journal of Pain Symptom Management 2013; 46:65-75.