[Video clip of a medical professional handing another medical professional a bag of five syringes]

Unidentified Healthcare Worker: There's five syringes.

Jerry Mendell, MD: This is a very significant day. 50 years of work went into this.

[Close up video of Gideon]

Erin Griffiths: We are here today to get Gideon's gene therapy. 

[MUSIC]

[Text on screen: FDA Approved Gene Therapy
Duchenne Muscular Dystrophy

NATIONWIDE CHILDREN'S
When your child needs a hospital, everything matters]

[Video clip of Gideon and his parents playing in a hospital room]

Gideon was actually diagnosed with Duchenne muscular dystrophy. 

[Text on screen: Erin Griffiths
Mother]

[Video clip of Gideon playing]

These boys are born normal, and then their muscles start slowing down and not working and so they don't live full lives.

[Various video clips of Jerry Mendell, MD, interacting with young patients]

[Text on screen: Jerry Mendell, MD
Principal Investigator, Center for Gene Therapy]

Mendell, MD: I saw my first Duchenne patient in 1969, and have worked on many phases of trying to introduce treatment. 

[Video clips of Mendell, MD, working in a lab]

Gene therapy is better than any drug therapy because it's one time delivery. If we treat patients very early, we can get to the disease before it wipes out all of the muscle or nerve.

[INAUDIBLE CONVERSATION]

Mendell, MD: We take the gene that's gonna be delivered now in 23 little vials. We deliver that over one and a half to two hours.

[Video clip of Gideon sitting in a chair]

Unidentified Healthcare Worker: Alrighty! First syringe is in! Yay!

[APPLAUSE]

[Video clip of Mendell, MD, and another healthcare professional moving Gideons legs, arms, and feet up and down]

Mendell, MD: If we exercise the extremities during the gene delivery, we can increase the blood flow to the muscles that are exercising.

Unidentified Healthcare Worker: Four, five, pull hard.

Mendell, MD: We've done this over 200 times in clinical trials, I think Gideon's going to do particularly well.

[Video clip of Mendell, MD, and the Griffiths family in a room]

Griffiths: We are very hopeful and thankful, Doctor Mendel, we can't thank him enough for everything he's done. 

[Video clip of Gideon receiving treatment]

Really, we're very blessed to have everybody that works with us.

[Video clip of Mendell, MD, Gideon, and Erin Griffiths sitting in a room with toys talking to Gideon]

Mendell, MD: People are really overwhelmed about what we're doing here, that makes you feel good, but makes you feel very humble too.

[Video clip of Gideon smiling while sitting in the chair he received his treatment in]

Griffiths: This is the only place that I would bring my kids. I expect to watch our little boy run around and play and be able to be involved in things and be a boy.

[gentle music]

[Text on screen: NationwideChildrens.org/Research
NATIONWIDE CHILDREN'S
When your child needs a hospital, everything matters.]