A research team at The Ohio State University College of
Medicine led by Courtney Hebert, MD, MS, was recently awarded a $1.9-million
R01 research award by the National Institute of Allergy and Infectious Diseases
for, “Automation and Multi-Site Validation of a Personalized Empiric Antibiotic
“The goal of this project is to help physicians choose the
best antibiotic to give to hospitalized patients with infections as soon as
possible,” explains Dr. Hebert. “It is important to start an appropriate antibiotic
early, before culture results are available. Choosing between antibiotics can
be a complicated decision, so we are developing a method that will help
physicians select antibiotics that have the best chance of working for each
Dr. Hebert and her team believe this tool will not only be
helpful for assigning antibiotics quickly but it could also reduce antibiotic
resistance in hospitals. Further research projects regarding multi-drug-resistant
organisms are possible based on the success of this tool.
Dr. Hebert’s team is multidisciplinary, spanning infectious
diseases, pharmacy, microbiology and biomedical informatics and is developing
its methodology at a second site at NorthShore University Health Systems in
Chicago. “We are hoping the multi-site design will help show that our methods
can be generalizable to other hospitals,” Dr. Hebert shares.
Dr. Hebert is as an assistant professor in Biomedical
Informatics at The Ohio State University. She is an alumna of Ohio State’s
College of Medicine and received her master’s degree from Ohio State’s College
of Public Health with a specialization in biomedical informatics. Her research
is inspired from her work as an infectious diseases clinician.