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Jianjie Ma, PhD

Department of Surgery

Email: ma.680@osu.edu

Website: http://surgery.osu.edu/cardiac/directory/​




Research Description

In the Ma lab, we study Ca2+ signaling in skeletal and cardiac muscles.  We have generated many transgenic knockout mice which plays vital roles in controlling Ca2+ signaling in junctional (sarcolemmal and sarcoplasmic reticulum (SR)) membranes.  Studies on these junctional molecules, including RYR, JP, TRIC-A/B, MG29, MG53 and MG56, not only provide us knowledge on molecular mechanism of muscle physiology but also extend our attempt to develop protein/peptides therapeutics for human health. Currently, we have 4 R01 funding from NIH.