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Nakamura, Tatsuya

Primary Appointment

Department Cancer Biology and Genetics
Human Cancer Genetics Program

Contact Information:

Office:

920 Biomedical Research Tower
460 W 12th Avenue
Columbus, OH 43210
Ph. (614) 688-3215
tatsuya.nakamura@osumc.edu 
 

Publications:
 

Gaudio E, Spizzo R, Paduano F, Luo Z, Efanov A, Palamarchuk A, Leber AS,
Kaou M, Zanesi N, Bottoni A, Costinean S, Rassenti LZ, Nakamura T, Kipps TJ,
Aqeilan RI, Pekarsky Y, Trapasso F, Croce CM. (2012) Tcl1 interacts with Atm
and enhances NF-κB activation in hematologic malignancies. Blood. 119(1):180-
187.

Havelange V, Pekarsky Y, Nakamura T, Palamarchuk A, Alder H, Rassenti L,
Kipps T, Croce CM. (2011) IRF4 mutations in chronic lymphocytic leukemia.
Blood. 118(10):2827-2829.

Orlovsky K, Kalinkovich A, Rozovskaia T, Shezen E, Itkin T, Alder H, Ozer HG,
Carramusa L, Avigdor A, Volinia S, Buchberg A, Mazo A, Kollet O, Largman C,
Croce CM, Nakamura T, Lapidot T, Canaani E. (2011) Down-regulation of
homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs
engraftment and reduces proliferation. Proc Natl Acad Sci U S A. 108(19):7956-
7961.

Fabbri M, Bottoni A, Shimizu M, Spizzo R, Nicoloso MS, Rossi S, Barbarotto E,
Cimmino A, Adair B, Wojcik SE, Valeri N, Calore F, Sampath D, Fanini F,
Vannini I, Musuraca G, Dell'Aquila M, Alder H, Davuluri RV, Rassenti LZ,
Negrini M, Nakamura T, Amadori D, Kay NE, Rai KR, Keating MJ, Kipps TJ,
Calin GA, Croce CM. (2011) Association of a microRNA/TP53 feedback
circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.
JAMA. 305(1):59-67.

Di Leva G, Gasparini P, Piovan C, Ngankeu A, Garofalo M, Taccioli C, Iorio
MV, Li M, Volinia S, Alder H, Nakamura T, Nuovo G, Liu Y, Nephew KP,
Croce CM. (2010) MicroRNA cluster 221-222 and estrogen receptor alpha
interactions in breast cancer. J Natl Cancer Inst. 102(10):706-721.

Pichiorri F, Okumura H, Nakamura T, Garrison PN, Gasparini P, Suh SS, Druck
T, McCorkell KA, Barnes LD, Croce CM, Huebner K. (2009) Correlation of
fragile histidine triad (Fhit) protein structural features with effector interactions
and biological functions. J Biol Chem. 284(2):1040-1049.

Garzon R, Volinia S, Liu CG, Fernandez-Cymering C, Palumbo T, Pichiorri F,
Fabbri M, Coombes K, Alder H, Nakamura T, Flomenberg N, Marcucci G, Calin
GA, Kornblau SM, Kantarjian H, Bloomfield CD, Andreeff M, Croce CM. (2008)
MicroRNA signatures associated with cytogenetics and prognosis in acute
myeloid leukemia. Blood. 111(6):3183-3189.

Guenther MG, Lawton LN, Rozovskaia T, Frampton GM, Levine SS, Volkert TL,
Croce CM, Nakamura T, Canaani E, Young RA. (2008) Aberrant chromatin at
genes encoding stem cell regulators in human mixed-lineage leukemia. Genes
Dev. 22(24):3403-3408.

Gregory GD, Vakoc CR, Rozovskaia T, Zheng X, Patel S, Nakamura T, Canaani
E, Blobel GA. (2007) Mammalian ASH1L is a histone methyltransferase that
occupies the transcribed region of active genes. Mol Cell Biol. 27(24):8466-8479.

Qin HR, Iliopoulos D, Nakamura T, Costinean S, Volinia S, Druck T, Sun J,
Okumura H, Huebner K. (2007) Wwox suppresses prostate cancer cell growth
through modulation of ErbB2-mediated androgen receptor signaling. Mol Cancer
Res. 5(9):957-965.

Nakanishi H, Nakamura T, Canaani E, Croce CM. (2007) ALL1 fusion proteins
induce deregulation of EphA7 and ERK phosphorylation in human acute
leukemias. Proc Natl Acad Sci U S A. 104(36):14442-14447.