The goal of cell-based therapy research is to discover substantial contributions to improve the health and welfare of patients, both human and veterinary. Research into cell-based therapy can further uncover the potential of certain cell types to repair, replace, or regenerate damaged cells, tissues, and even organs. Medical researchers at Ohio State are working to understand the use of cell-based therapies and anticipate using technologies derived from stem cell research to treat a wider variety of diseases including cancer, diabetes, Parkinson's disease, acute and chronic myocardial ischemia, spinal cord injuries, inflammatory diseases and muscle damage, among a number of other impairments, injuries and conditions.

Many researchers have worked with stem cells for these therapies because of their remarkable potential to develop into many different cell types in the body and tremendous capacity to undergo regeneration in response to injury. However, progenitor cells, which have the ability to develop into another specific type of cell, and primary cells among other cell types should be considered for cell-based therapies as well. A 2018 study by The Ohio State University Wexner Medical Center discovered that human immune cells share similar capabilities to stem cells in encouraging healing and helping end prolonged inflammation.

Our Researchers

Alicia L. Bertone, DVM, PhD
Bharat Bhushan, PhD, MBA
Denis C. Guttridge, PhD
Gregg Allen Hadley, PhD
Nicanor I. Moldovan, PhD
Philip G. Popovich, PhD
Vincent Pompili, MD, FACC
Xiaoming (Shawn) He, PhD
Jeffery J. Auletta, MD
Jon R. Parquette, PhD
Jose Javier Otero, MD, PhD
Michael F. Tweedle, PhD
Michael V. Knopp, MD, PhD
Mingjun Zhang, PhD, DSc
Qi-En Wang, PhD
Hiranmoy Das, PhD
Robert J. Lee, PhD