582 Biomedical Research Tower
460 W. 12th Ave.
Columbus, OH 43210

614-685-9149
Motoyasu.Saji@osumc.edu

Research Interest

My personal goals in medical science are to identify the mechanisms of tumorigenesis and tumor progression, including dedifferentiation and metastasis, in thyroid cancer, and to apply these results to clinical diagnosis and treatment.  Dr. RIngel and focused on defining the roles of key signaling pathways in thyroid cancer progression, including Akt, Pak and Erk. Using human tumors, in vitro systems and mouse models, we have defined the roles of these and other signaling cascades in thyroid cancer development and progression.