• Medical Journal, 2013 - present
• Current Vascular Pharmacology, 2013
• International Journal of Physical Medicine and Rehabilitation, 2013
• Journal of Visualized Experiments, 2014
• Austin Journal of Molecular and Cell Biology, 2015

Compositions and Methods Modulating MG29 for the Treatment of Diabetes

Compositions and Methods Modulation MG29 for the Treatment of Diabetes, Kidney and Bone Dysfunction

Hu,C,P; Han,S,H; Lui,W,Y; Hsu,H,C; Lin,Y,M; Lin,P,H; Chen,L,R; Hsieh,H,G; Kuo,P,T; Peng,F,K; CHANG,C,M. "MONOCLONAL-ANTIBODIES AGAINST ANTIGENS EXPRESSED ON HUMAN HEPATOCELLULAR-CARCINOMA CELLS." HEPATOLOGY. Vol. 6, no. 6. (November 1986.): 1396-1402

Shenoy S, Chackalaparampil, I., Bagrodia, S., Lin PH, and Shalloway D. "Role of p34cdc2-mediated phosphorylations in two-step activation of pp60c-src during mitosis." Proc. Natl. acad. Sci. USA. Vol. 89, (January 1992.): 7237-7241

Shalloway, D., Bagrodia, S., Chackalaparampil, I., Shenoy S, Lin PH, and Taylor, S. "c-Src and mitosis." Ciba foundation symposium. Vol. 170, (January 1992.): 248-275

Lin,P,H; Shenoy,S; Galitski,T; Shalloway,D. "TRANSFORMATION OF MOUSE CELLS BY WILD-TYPE MOUSE C-SRC." ONCOGENE. Vol. 10, no. 2. (January 1995.): 401-405

Chackalaparampil,I; PERI,A; Nemir,M; McKee,M,D; Lin,P,H; MUKHERJEE,B,B; MUKHERJEE,A,B. "Cells in vivo and in vitro from osteopetrotic mice homozygous for c-src disruption show suppression of synthesis of osteopontin, a multifunctional extracellular matrix protein." ONCOGENE. Vol. 12, no. 7. (April 1996.): 1457-1467

Pei-Hui Lin, Leslie H. Huang, Ruth Steward. "Cactin, a conserved protein that interacts with the Drosophila IkB proteinCactus and modulates its function." Mechanisms of Development. Vol. 94, (January 2000.): 57-65

Pei-Hui Lin, Leslie. Huang, Ruth Steward. "Drosophila Embryo:dorsal-ventral specifiction." The Encyclopedia of Life Science. Vol. N/A, (January 2003.): N/A-

Lin P., Pan Z., Zheng, L., Li, N., Danielpour D., Ma J.. "Overexpression of Bax sensitizes prostate cancer cells to TGF-β induced apoptosis." Cell Research. Vol. 15, (January 2005.): 150-156

Cai, C., Ferrante, C., Lin, P., Foskett, J.K., Boulianne, G., Danielpour, D., and Ma, J.. "The presenilinloop peptide perturbs intracellular Ca homeostasis and accelerates apoptosis." J. Biol. Chem. Vol. 281, (January 2006.): 16649-16655

Hirata,Yutaka; Brotto,Marco; Weisleder,Noah; Chu,Yi; Lin,Peihui; Zhao,Xiaoli; Thornton,Angela; Komazaki,Shinji; Takeshima,Hiroshi; Ma,Jianjie; Pan,Zui. "Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes." BIOPHYSICAL JOURNAL. Vol. 90, no. 12. (June 2006.): 4418-4427

Ko,Jae-Kyun; Choi,Kyoung-Han; Pan,Zui; Lin,Peihui; Weisleder,Noah; Kim,Chul-Woo; Ma,Jianjie. "The tail-anchoring domain of Bfl1 and HCCS1 targets mitochondrial membrane permeability to induce apoptosis." JOURNAL OF CELL SCIENCE. Vol. 120, no. 16. (August 2007.): 2912-2923

Yazawa,Masayuki; Ferrante,Christopher; Feng,Jue; Mio,Kazuhiro; Ogura,Toshihiko; Zhang,Miao; Lin,Pei-Hui; Pan,Zui; Komazaki,Shinji; Kato,Kazuhiro; Nishi,Miyuki; Zhao,Xiaoli; Weisleder,Noah; Sato,Chikara; Ma,Jianjie; Takeshima,Hiroshi. "TRIC channels are essential for Ca2+ handling in intracellular stores." Nature. Vol. 448, no. 7149. (July 2007.): 78-82

Li,Na; Zheng,Lin; Lin,Peihui; Danielpour,David; Pan,Zui; Mai,Jianjie. "Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells." JOURNAL OF CELLULAR PHYSIOLOGY. Vol. 216, no. 1. (July 2008.): 172-179

Li,Na; Lin,Peihui; Cai,Chuanxi; Pan,Zui; Weisleder,Noah; Ma,Jianjie. "The amino-terminal peptide of Bax perturbs intracellular Ca2+ homeostasis to enhance apoptosis in prostate cancer cells." AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. Vol. 296, no. 2. (February 2009.): C267-C272

Cai,Chuanxi; Masumiya,Haruko; Weisleder,Noah; Matsuda,Noriyuki; Nishi,Miyuki; Hwang,Moonsun; Ko,Jae-Kyun; Lin,Peihui; Thornton,Angela; Zhao,Xiaoli; Pan,Zui; Komazaki,Shinji; Brotto,Marco; Takeshima,Hiroshi; Ma,Jianjie. "MG53 nucleates assembly of cell membrane repair machinery." NATURE CELL BIOLOGY. Vol. 11, no. 1. (January 2009.): 56-U108

Calcraft,Peter,J; Ruas,Margarida; Pan,Zui; Cheng,Xiaotong; Arredouani,Abdelilah; Hao,Xuemei; Tang,Jisen; Rietdorf,Katja; Teboul,Lydia; Chuang,Kai-Ting; Lin,Peihui; Xiao,Rui; wang,chunbo; Zhu,Yingmin; Lin,Yakang; Wyatt,Christopher,N; Parrington,John; Ma,Jianjie; Evans,A,Mark; Galione,Antony; Zhu,Michael,X. "NAADP mobilizes calcium from acidic organelles through two-pore channels." NATURE. Vol. 459, no. 7246. (May 2009.): 596-U130

Zhao,Xiaoli; Yamazaki,Daiju; Park,Ki,Ho; Komazaki,Shinji; Tjondrokoesoemo,Andoria; Nishi,Miyuki; Lin,Peihui; Hirata,Yutaka; Brotto,Marco; Takeshima,Hiroshi; Ma,Jianjie. "Ca2+ Overload and Sarcoplasmic Reticulum Instability in tric-a Null Skeletal Muscle." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 285, no. 48. (November 2010.): 37370-37376

Wang,Xianhua; Xie,Wenjun; Zhang,Yi; Lin,Peihui; Han,Liang; Han,Peidong; Wang,Yanru; Chen,Zheng; Ji,Guangju; Zheng,Ming; Weisleder,Noah; Xiao,Rui-Ping; Takeshima,Hiroshi; Ma,Jianjie; Cheng,Heping. "Cardioprotection of Ischemia/Reperfusion Injury by Cholesterol-Dependent MG53-Mediated Membrane Repair." CIRCULATION RESEARCH. Vol. 107, no. 1. (July 2010.): 76-U155

Tong,Xin; Gui,Hongxing; Jin,Feng; Heck,Bryan,W; Lin,Peihui; Ma,Jianjie; Fondell,Joseph,D; Tsai,Chih-Cheng. "Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway." EMBO REPORTS. Vol. 12, no. 5. (May 2011.): 428-435

Zhu,Hua; Lin,Peihui; De,Gejing; Choi,Kyoung-Han; Takeshima,Hiroshi; Weisleder,Noah; Ma,Jianjie. "Polymerase Transcriptase Release Factor (PTRF) Anchors MG53 Protein to Cell Injury Site for Initiation of Membrane Repair." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 286, no. 15. (April 2011.): 12820-12824

Weisleder,Noah; Lin,Peihui; Zhao,Xiaoli; Orange,Matthew; Zhu,Hua; Ma,Jianjie. "Visualization of MG53-mediated cell membrane repair using in vivo and in vitro systems.." Journal of visualized experiments : JoVE. Vol. N/A, no. 52. (January 2011.): 2717-

Waddell,Leigh,B; Lemckert,Frances,A; Zheng,Xi,F; Tran,Jenny; Evesson,Frances,J; Hawkes,Joanne,M; Lek,Angela; Street,Neil,E; Lin,Peihui; Clarke,Nigel,F; Landstrom,Andrew,P; Ackerman,Michael,J; Weisleder,Noah; Ma,Jianjie; North,Kathryn,N; Cooper,Sandra,T. "Dysferlin, Annexin A1, and Mitsugumin 53 Are Upregulated in Muscular Dystrophy and Localize to Longitudinal Tubules of the T-System With Stretch." JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 70, no. 4. (April 2011.): 302-313

Nishi,Miyuki; Aoyama,Fumiyo; Kisa,Fumihiko; Zhu,Hua; Sun,Mingzhai; Lin,Peihui; Ohta,Hiroya; Van,Bo; Yamamoto,Shinichiro; Kakizawa,Sho; Sakai,Hideki; Ma,Jianjie; Sawaguchi,Akira; Takeshima,Hiroshi. "TRIM50 Protein Regulates Vesicular Trafficking for Acid Secretion in Gastric Parietal Cells." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 287, no. 40. (September 2012.): 33523-33532

Lin,Peihui; Zhu,Hua; Cai,Chuanxi; Wang,Xianhua; Cao,Chunmei; Xiao,Ruiping; Pan,Zui; Weisleder,Noah; Takeshima,Hiroshi; Ma,Jianjie. "Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair." FASEB JOURNAL. Vol. 26, no. 5. (May 2012.): 1875-1883

Weisleder,Noah; Takizawa,Norio; Lin,Peihui; Wang,Xianhua; Cao,Chunmei; Zhang,Yan; Tan,Tao; Ferrante,Christopher; Zhu,Hua; Chen,Pin-Jung; Yan,Rosalie; Sterling,Matthew; Zhao,Xiaoli; Hwang,Moonsun; Takeshima,Miyuki; Cai,Chuanxi; Cheng,Heping; Takeshima,Hiroshi; Xiao,Rui-Ping; Ma,Jianjie. "Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy." SCIENCE TRANSLATIONAL MEDICINE. Vol. 4, no. 139. (June 2012.): 139ra85-

He,Bo; Tang,Ru-Hang; Weisleder,Noah; Xiao,Bin; Yuan,Zhenhua; Cai,Chuanxi; Zhu,Hua; Lin,Peihui; Qiao,Chunping; Li,Jianbin; Mayer,Christina; Li,Juan; Ma,Jianjie; Xiao,Xiao. "Enhancing Muscle Membrane Repair by Gene Delivery of MG53 Ameliorates Muscular Dystrophy and Heart Failure in delta-Sarcoglycan-deficient Hamsters." MOLECULAR THERAPY. Vol. 20, no. 4. (April 2012.): 727-735

Tjondrokoesoemo A, Li, N., Lin P., Pan, Z., Ferrante, C.J., Shirokova, N., Brotto, M, Weisleder, N., and Ma, J.. "Cross-talk between IP3 receptor and ryanodine receptor underlies activation of stress-induced Ca2+ sparks in mammalian skeletal muscle." J. Biol. Chem. Vol. 288, (January 2013.): 2103-2109

Yi,Jae-Sung; Park,Jun,Sub; Ham,Young-Mi; Nguyen,Nga; Lee,Na-Rae; Hong,Jin; Kim,Bong-Woo; Lee,Hyun; Lee,Chang-Seok; Jeong,Byung-Cheon; Song,Hyun,Kyu; Cho,Hana; Kim,Yoon,Ki; Lee,Jae-Seon; Park,Kyong,Soo; Shin,Haksub; Choi,Inho; Lee,Seung,Hee; Park,Woo,Jin; Park,Shi-Young; Choi,Cheol,Soo; Lin,Peihui; Karunasiri,Malith; Tan,Tao; Duann,Pu; Zhu,Hua; Ma,Jianjie; Ko,Young-Gyu. "MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling." Nature Communications. Vol. 4, (August 2013.): 2354-

Yanlin Jia*, Ken Chen*, Peihui Lin*, Gissela Lieber, Xiaoli Zhao, Miyuki Nishi, Rosalie Yan, Zhen Wang, Yonggang Yao, Yu Li, Bryan A. Whitson, Pu Duann, Haichang Li, Hua Zhu, Hiroshi Takeshima, Robbie L. McLeod, John Hunter, Noah Weisleder, Chunyu Zeng and Jianjie Ma. "Treatment of acute lung injury by targeting MG53-mediated cll membrane repair." Nature Communication. Vol. 18, no. 5. (July 2014.): 4387-

Xinyu Zhou, Peihui Lin, Daiju Yamazaki, Ki Ho Park, Shinji Komazaki, S.R. Wayne Chen, Hiroshi Takeshima and Jianjie Ma. "Roles of TRIC Channels in Sarcoplasmic Reticulum/Endoplasmic Reticulum Calcium Homeostasis." Circulation Research. Vol. 114, no. 4. (January 2014.): 706-16

Ki Ho Park, Noah Weisleder, Jingsong Zhou, Kristyn Gumpper, Xinyu Zhou, Pu Duann, Jianjie Ma and Pei-Hui Lin. "Assessment of calcium sparks in intact skeletal muscles." Journal of Visualized Experiments. Vol. N/A, (February 2014.): N/A-

Mingzhai Sun, Jiaqing Huang, Filiz Bunyak, Kristyn Gummper, Gejing De, Mathew Sermersheim, George Liu, Pei-Hui Lin, Kannappan Palaniappan and Jianjie Ma. "Superresolution microscope image reconstruction by spatiotemporal object decomposition and association: application in resolving t-tubule structure in skeletal muscle." Optics Express. Vol. 22, no. 10. (July 2014.): 12160-

Mingzhai Sun, Jiaqing Huang, Filiz Bunyak, Kristyn Gumpper, Gejing De, Matthew Sermersheim, George Liu, Pei-Hui Lin, Kannappan Palaniappan and Jianjie Ma. "Superresolution microscope image reconstruction by spatiotemporal object decomposition and association: application in resolving t-tubule structure in skeletal muscle." Optics Express. Vol. 22(10)12160-12176, (May 2014.): 12160-76. doi: 10.1364/OE.22.012160

Deng Y, Sun M, Lin P-H, Ma J, Shaevitz JW. "Spatial Covariance Reconstructive (SCORE) Super-Resolution Fluorescence Microscopy." PLoS ONE. Vol. 9, no. 4. (July 2014.): e94807-

Liu J, Zhu H, Zheng Y, Xu Z, Li L, Tan T, Park KH, Hou J, Zhang C, Li D, Li R, Liu Z, Weisleder N, Zhu D, Lin P, Ma J.. "Cardioprotection of recombinant human MG53 protein in a porcine model of ischemia andreperfusion injury." J Mol Cell Cardiol.. Vol. 80, (February 2015.): 10-19

Yajuan Xiao, Jianxun Yi, Changling Ma, Shaoping Wu, Guo Luo, Xiulong Xu, Pei-Hui Lin, Jun Sun and Jingsong Zhou. "Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression." Physiological Reports. Vol. 3, no. 1. (January 2015.): e12271-

Pei-Hui Lin#, Pu Duann, Shinji Komazaki, Ki Ho Park, Haichang Li, Mingzhai Sun, Mathew Sermersheim, Kristyn Gummper; John Parrington, Antony Galione, Mark Evans, Michael X. Zhu and Jianjie Ma.. "Lysosomal two-pore channel subtype 2 regulates lysosome signaling during autophagy in skeletal muscle.." Journal Biological Chemistry. Vol. 290, no. 6. (February 2015.): 3377-3389

Haichang, Pu Duann, Pei-Hui Lin, Li Zhao, Zhaobo Fan, Xinyu Zhou , Mingzhai Sun, Minghuan Fu, Matthew Orange, Matthew Sermersheim, Hanley Ma, Steven M. Steinberg, Robert Higgins, Hua Zhu, Tao Tan, Jianjun Guan, and Jianjie Ma. "MG53 promotes wound healing and reduces scar formation by facilitating cell membrane repair and controlling myofibroblast differentiation." Journal Biological Chemistry 290 (40): 24592-24603 (2015). Vol. 290, no. 40. (September 2015.): 24592-24603

Pu Duann, Haichang Li, Peihui Lin, Tao Tan, Zhen Wang, Ken Chen, Xinyu Zhou, Kristyn Gumpper, Thomas Ludwig, Peter J. Mohler, Brad Rovin, William Abraham, Chunyu Zeng, and Jianjie Ma. "MG53-mediated cell membrane repair protects against acute kidney injury." Science Translational Medicine. Vol. 7, (March 2015.): 279ra36-

Peihui Lin*, Chuanxi Cai*, Hua Zhu* (*co-first authors), Jae-Kyun Ko, Moonsun Hwang , Tao Tan, Zui Pan, Irina Korichneva and Jianjie Ma.. "Zinc Binding to MG53 Facilitates Repair of Injury to Cell Membrane." Journal Biological Chemistry. Vol. 290, no. 22. (May 2015.): 13830-13839

Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, ….Peihui Lin….et. al. "Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (2nd edition." Autophagy

• Present Graduate Student Admission Process, The Ohio State University, Columbus, OH
• 2015 - present Admission Screener, The Ohio State University Wexner Medical Center
• 2011 Xinyu Zhou - graduate student, Dr. Jianjie Ma’ Lab
• 2013 Matt Sermersheim - graduate student, Dr. Jianjie Ma’ Lab
• 2013 Kristyn Gumpper - graduate student, Dr. Jianjie Ma’ Lab
• 2001 - 2002 Dr. Erin O’Neill - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2001 - 2003 Dr. Claude Collet - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2001 - 2004 Dr. Xu Wang - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2004 - 2005 Dr. Henrietta Szapponos - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2001 - 2006 Dr. Yutaka Hirata - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2004 - 2006 Dr. Noah Weisleder - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2002 - 2007 Na Li - graduate student, Dr. Jianjie Ma’ Lab
• 2002 - 2007 Lin Zheng - graduate student, Dr. Jianjie Ma’ Lab
• 2003 - 2007 Jae-Kyun Ko - graduate student, Dr. Jianjie Ma’ Lab
• 2003 - 2007 Xiaoli Zhao - graduate student, Dr. Jianjie Ma’ Lab
• 2007 Christopher Ferrante - graduate student, Dr. Jianjie Ma’ Lab
• 2003 - 2008 Angela Thornton - graduate student, Dr. Jianjie Ma’ Lab
• 2004 - 2008 Dr. Chuanxi Cai - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2008 Choon Kee Min - graduate student, Dr. Jianjie Ma’ Lab
• 2008 Srilatha Simhadri - graduate student, Dr. Jianjie Ma’ Lab
• 2007 - 2009 Dr. Xiaoli Zhao - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2005 - 2010 Moon-Sun Hwang - graduate student, Dr. Jianjie Ma’ Lab
• 2007 - 2010 Kyoung-Han Choi - graduate student, Dr. Jianjie Ma’ Lab
• 2008 - 2010 Dr. Hua Zhu - postdoctoral fellow, Dr. Jianjie Ma’ Lab
• 2007 - 2011 Andoria Tjondrokoesoemo - graduate student, Dr. Jianjie Ma’ Lab
• 2008 - 2012 Matt Orange - graduate student, Dr. Jianjie Ma’ Lab
• 2009 - 2014 Dr. GeJing De - postdoctoral fellow, Dr. Jianjie Ma’ Lab