Regenerative Medicine News

Reimbursement Strategies WebinarPlanning Your Payment Strategy in Early Product Development in Regenerative Medicine Sponsored by: CIRM and ARM – The Alliance for Regenerative Medicine ​ Webinar Information:Date: June 20 10 to 11 am Pacific TimeFee ...[Read More]

Induction of Pluripotency in Mouse Somatic Cells with Lineage SpecifiersThe authors report that, during mouse somatic cell reprogramming, pluripotency can be induced with lineage specifiers that are pluripotency rivals to suppress embryonic stem cel ...[Read More]

Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage CommitmentUnderstanding the topological configurations of chromatin may reveal valuable insights into how the genome and epigenome act in concert to control cell fate d ...[Read More]

Sequential Introduction of Reprogramming Factors Reveals a Time-Sensitive Requirement for Individual Factors and a Sequential EMT-MET Mechanism for Optimal ReprogrammingPresent practices for reprogramming somatic cells to induced pluripotent stem ce ...[Read More]

Deficits in Human Trisomy 21 iPSCs and NeuronsDown syndrome (trisomy 21) is the most common genetic cause of intellectual disability, but the precise molecular mechanisms underlying impaired cognition remain unclear. Elucidation of these mechanisms ...[Read More]

High Throughput Screening for Inhibitors of Rest in Neural Derivatives of Human Embryonic Stem Cells Reveals a Chemical Compound that Promotes Expression of Neuronal GenesHigh-throughput screening of a library of 6,984 compounds with luciferase-assa ...[Read More]

An Epigenetic Signature of Developmental Potential in Neural Stem Cells and Early NeuronsResearchers interrogated the epigenome during differentiation of embryonic stem cell (ESC)-derived neural stem cells (NSCs) to immature GABAergic interneurons. ...[Read More]

Three-Dimensional Co-Cultures of Human Endothelial Cells and Embryonic Stem Cell-Derived Pericytes Inside a Microfluidic DeviceScientists engineered three-dimensional constructs of vascular tissue inside microchannels by injecting a mixture of human ...[Read More]

The Tumorigenicity of iPS Cells and Their Differentiated DerivatesUndifferentiated induced pluripotent stem cells (iPSCs), iPSC derivates from induced differentiation (iPSC-derivates), iPSC-derivated cardiomyocytes were subcutaneously injected into ...[Read More]

The Establishment of Mouse Embryonic Stem Cell Cultures on 96-Well Plates for High-Throughput ScreeningThe application of embryonic stem (ES) cells can be a useful tool for drug discovery and toxicology. Researchers suggest the high-throughput scree ...[Read More]