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Third-Party Mesenchymal Stem Cells Improved Human Islet Transplantation in a Humanized Diabetic Mouse Model 

 

Third-Party Mesenchymal Stem Cells Improved Human Islet Transplantation in a Humanized Diabetic Mouse Model
Scientists determined whether co-transplantation of human bone marrow derived mesenchymal stem cells could prevent immune rejection and improve human islet transplantation in a humanized NSG mouse model. Human immunity was rebuilt and maintained in NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ mice up to 13 weeks after intraperitoneal injection of mature human peripheral blood mononuclear cells.

 

Posted on 20-Jun-13 by Suri, Prerna
Tags: Science and Industry News
 
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