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Gayle Gordillo MD, FACS

Gayle Gordillo MD, FACS   
Associate Professor of Plastic Surgery, The Ohio State University
Phone: (614) 293-3748
Email: Gayle.Gordillo@osumc.edu










This group works on multiple different projects studying mechanisms regulating angiogenesis in both wound healing and endothelial cell tumor biology. The group has expertise in the design and execution of both sponsored clinical trials and investigator initiated clinical and translational research.  Additional funded project also include work on thermal burns, oxygen imaging, and nutritional interventions to treat diabetes and stroke.
Team Members
Lynn Lambert, RT, CHT – research administrator
Urmila Gnyawali, RN – research nurse
Bibechana Subedi, RN – research nurse
Michelle Giovannelli RN, WOCN - wound nurse
Savita Khanna, PhD – assistant professor of surgery
Sashwati Roy, PhD – associate professor of surgery
Chandan Sen, PhD – professor of surgery
Research Interests
Angiogenesis
Chronic wounds
Translational research
Tissue oxygenation
Cutaneous repair and regeneration
Selected Publications
Roy S, Dickerson R, Khanna S, Collard E, Gnyawali U, Gordillo GM, Sen CK. Particulate β-glucan induces TNF-α production in wound macrophages via a redox-sensitive NF-κβ-dependent pathway. Wound Repair and Regen 2011 May;19(3):411-9.

Patt BT, Jarjoura D, Lambert L, Roy S, Gordillo G, Schlanger R, Sen CK, Khayat RN; Prevalence of obstructive sleep apnea in patients with chronic wounds, J Clin Sleep Med. 2010 Dec 15;6(6):541-4.

Xu RX, Huang K, Qin R, Huang J, Xu JS, Ding L, Gnyawali US, Gordillo GM, Gnyawali SC, Sen CK. Dual-mode imaging of cutaneous tissue oxygenation and vascular function. J Vis Exp. 2010 Dec 8;(46). pii: 2095. doi: 10.3791/2095.

Jacobs BJ, Anzarut A, Guerra S, Gordillo G, Imbriglia JE. Vascular Anomalies of the Upper Extremities. J Hand Surg Am 2010 Oct;35(10):1703-9.

Gordillo GM, Fang H, Park HA, Roy S.  Nox-4 Dependent Nuclear H2O2 Drives DNA Oxidation Resulting in 8-OHdG as Urinary Biomarker and Hemangioendothelioma Formation.  Antioxid Redox Signal. 2010 Apr 15;12(8): 933-43

Khanna S, Biswas S, Shang Y, Collard E, Azad A, Kauh C, Bhasker V, Gordillo GM, Sen CK, Roy S. Macrophage dysfunction impairs resolution of inflammation in the wounds of diabetic mice.  PLoS One 2010 March 4;5(3):e9539.

Roy S, Biswas S, Khanna S, Gordillo GM, Bergdall V, Green J, Marsh CB, Gould LJ, Sen CK; Characterization of a pre-clinical model of chronic ischemic wound. Physiol Genomics. 2009 May 13;37(3):211-24.

Gordillo GM, Fang H, Khanna S, Harper J*,Phillips GS, Sen CK; Oral blueberry extract treatment of endothelial cell tumor enhances survival; Antioxidants and Redox Signaling 2009 11(1):47-57.

Gordillo GM, Roy S, Khanna S, Schlanger R, Khandelwal S, Phillips GS, Sen CK; Topical Oxygen Therapy Induces VEGF Expression and Improves Closure of Clinically Presented Chronic Wounds; Clinical and Experimental Pharmacology and Physiology 2008; 35(8):957-964.

Roy S, Patel D, Khanna S, Gordillo G, Biswas S, Friedman A, Sen   CK.  Genome-wide analysis of blood vessels laser captured from human skin and chronic wound-edge tissue. Proceedings of the National Academy of Science 2007 Sept 4;104(36):14472-7