Name: W. David Arnold

Email: william.arnold@osumc.edu

Department: Neurology

Lab Manager/Dept Contact: Prameela Bobbili

Lab Manager/Dept Contact Email: Prameela.bobbili@osumc.edu

Preferred Method of Contact: Faculty email

Mentor & Lab Website: http://u.osu.edu/arnold.780/

Previous Mentoring: Yes (funded)

Category of research: Translational

Research Description: The focus of the lab is translational neuromuscular physiology with a particular emphasis on age-related loss of physical function as well as loss of motor function in hereditary neuromuscular disorders.

We are pursuing preclinical and clinical projects in the following areas:

  1. Motor neuron degeneration and repair in age-related loss of physical function
  2. Therapeutics in peripheral nerve injury and repair
  3. Effects of muscle alterations on motor unit maintenance and degeneration
  4. Investigating central nervous system disease burden in patients with myotonic dystrophy type 1 (DM1) and the role of motor neuron dysfunction in motor impairment
  5. Investigating ranolazine at a therapeutic for dystrophic and nondystrophic forms of myotonia

Specific areas of Research Emphasis: Aging, Musculoskeletal Disorders, and Neurologic Disorders


Name: Stephen Kolb

Email: stephen.kolb@osumc.edu

Department: Neurology, Molecular and Cellular Biochemistry

Preferred Method of Contact: Faculty Email

Previous Mentoring: Yes (funded)

Category of research: Basic

Specific areas of Research Emphasis: Neuroscience, neurological disorders


Name: Michel Torbey

Email: michel.torbey@osumc.edu

Department: Neurology

Name of Lab Manager: Ana Gomez

Email: Ana.Gomez@osumc.edu

Previous Mentoring: Yes (funded)

Category of research: Basic; Translational

Research Description 1: My laboratory work is on neurprotective mechanisms post stroke, cardiac arrest and traumatic brain injury. Currently we are working on testing a novel molecule and its neuroprotective effects after traumatic brain injury in rats. We postulate that this new drug will decrease extent of cerebral edema and enhance neuronal count after TBI in rats.

Research Description 2: The Stroke and Neurocritical Care Division is currently actively involved in a multitude of clinical trials focusing on the acute management of stroke and traumatic brain injury. We are investigating the role of aggressive glucose control in acute stroke. In traumatic brain injury we are looking at the neuroprotective effective of progesterone in acute TBI.

Specific areas of Research Emphasis: Emergency Medicine; Trauma; Neuroscience


Name: Yousef Hannawi

Email: yousef.hannawi@osumc.edu

Department: Neurology

Preferred Method of Contact: Faculty email

Previous Mentoring: Yes (funded)

Category of research: Clinical

Research Description: I am interested in understanding the outcome and symptomatology of neurological insults by applying advanced neuroimaging tools and analytical methods. I am currently doing projects using MRI technology to understand the outcome of stroke and white matter disease in addition to other acute neurological insults. The aim is to develop novel tools for mapping the brain structure and function in the disease state.

Specific areas of Research Emphasis: Critical Care; Neurologic Disorders; Neuroscience