Structural & Functional Assessments (Core A)

OSU Vision Sciences Research Core Program

Structural and Functional Assessments (SFA) Core

Director: Andy Fischer, PhD

Co-director: Colleen Cebulla, MD, PhD

Lab manager: Tyler Heisler-Taylor, PhD

ERG: Julie Racine, PhD

Email: vsrcpmanagement@buckeyemail.osu.edu

Please cite P30EY032857 in all publications that make use of the Ohio State University Vision Science Research Core Program (OSU-VSRCP).

“Services are performed at the OSU Vision Sciences Research Core Program under P30EY032857.”

Services include:

  • Technician time & Assisted equipment use ($75/hr)
  • Animal handling, husbandry, or other expertise ($40/hr)
  • Equipment or procedure training (Free!)

Please reach out or schedule a consultation through eRAMP!

eRAMP

Equipment includes:

Expanded equipment access and data gathering on structural and functional analysis

ColorFundus

Core A focuses on physiological and structural data gathered from the cellular level (in vitro) to animal models (in vivo) of eye diseases. The work often requires expensive equipment and technical expertise that individual researchers can’t afford but institutions can, such as:

 

  • Angiography
  • Electrophysiology
  • Fundus photography
  • Photocoagulation laser systems
  • State-of-the-art microscopes
  • Optical coherence tomography
  • Tonometry

At The Ohio State University, some of this advanced equipment will be duplicated to serve two locations — small animal research at the new Pelatonia Research Center and a wide range of animal research at the traditional OSU Wexner Medical Center campus.

The Core A team, directed by DOVS faculty Colleen Cebulla, MD, PhD, and Department of Neuroscience faculty Andy Fischer, PhD, will also provide consulting expertise to scientists and labs that need additional analysis or help with developing specific research methods. Such technical support can also assist funded scientists in completing additional studies within their funded projects

For example, when studying macular degeneration, glaucoma or inherited retinal dystrophy, a researcher may study one aspect of a condition, such as histology. The P30 cores offer the ability for the same scientist to expand their work by taking in vivo pictures over time and some electrophysiologic functions of the diseased tissues or eyes.

“This P30 grant will enhance research of funded investigators and also help faculty without grants who need critical pilot data in order to write a strong new grant proposal." - Dr. Moroi. 

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