Professor, Microbial Infection and Immunity
786 Biomedical Research Tower
460 W 12th Ave, Columbus OH 43210
Stephanie.Seveau@osumc.edu
614-247-7671
Membership: Infectious Diseases Institute
Research Interests
Dr. Seveau's laboratory focuses on molecular mechanisms underlying host-pathogen interactions using Listeria monocytogenes as a model facultative intracellular pathogen. Specific projects currently are to: (1) establish how L. monocytogenes infects mammalian cells and tissues, (2) determine the molecular basis and outcomes of host-cell signaling in response to listeriolysin O, the major virulence factor of L. monocytogenes and a member of the cholesterol-dependent cytolysin (CDC) toxins, and (3) elucidate the mechanisms underlying the anti-toxin and immune-modulatory activities of antimicrobial peptides that belong to the defensin family.
Laboratory
770 Biomedical Research Tower
460 W 12th Ave, Columbus OH 43210
614-247-7674
Lab Website
Personnel
Heba Amer, Research Technician, heba.amer@osumc.edu
Maddie Chamberlain, Undergraduate Student, chamberlain.206@osu.edu
Madalyn Fields, Graduate Student, madalyn.fields@osumc.edu
Sri Godavarthi, Undergraduate Student, godavarthi.4@osu.edu
Emma Mills, Undergraduate Student, mills.1041@osu.edu
Katianne Napier, Undergraduate Student, napier.189@osu.edu
Marilynn Ng, Research Technician, marilynn.ng@osumc.edu
Isabella Prislusky, Graduate Student, prislusky.2@osu.edu
Sindhu Sharma, Undergraduate Student, sharma.1079@osu.edu
Abby Spencer, Undergraduate Student, spencer.840@osu.edu