- About this researcher
Anasuya Sarkar
Associate Professor
Internal Medicine
Academic information
- Department: Internal Medicine
Research interests
- Translational research
- Vascular injury in pulmonary infections
- Sepsis and acute lung injury
- Regulation of monocyte/macrophage function and host immune responses
- Cellular mechanisms and metabolic changes regulating inflammasome function
- Exosome biology and immunology
About
Biography
I am an Associate Professor at The Ohio State University (OSU) in the Department of Internal Medicine where she leads a research program focused on host immune responses in sepsis and sepsis induced acute lung injury. I received my PhD in Molecular and Cellular Biology in India. I then perused my postdoctoral training at OSU where I later joined as a faculty member. My research program has been continuously supported by extramural and intramural grants. I am an ad-hoc reviewer of multiple study sections (American Thoracic Society, Alpha-1 Foundation and NIH). In addition to my research program, I am also extremely passionate career development, mentoring and teaching the next generation scientists. I am the Graduate Faculty Liaison, Biomedical Sciences Graduate Program (BSGP), OSU, College of Medicine (Physiology and Cellular Biology Emphasis Area) for BSGP graduate program. I am also currently involved in physiology and grantsmanship training courses for Human Physiology and Diseases (PHYSIO 3100) and BSGP programs. I am an active member of FAME and WIMS involved in academic development of junior faculty and women in scientific career pathways.
I am a PhD trained basic scientist pursuing translational research with a long-term goal to develop a new class of therapeutics to combat vascular injury in pulmonary infections, sepsis and acute lung injury. The underlying tenet of my research program is focused on regulation of monocyte/macrophage function and host immune responses, cellular mechanisms and metabolic changes regulating inflammasome function, exosome biology and immunology to uncover strategies to exploit the immune system for the benefit of human health.
Credentials
Education
- Postdoctoral Research
- Ohio State University Wexner Medical Center, Columbus, United States of America
- PhD - Molecular and Cellular Biology
- CSIR Indian Institute of Chemical Biology, Jadavpur University, West Bengal, India
- MS - Zoology
- University of Kolkata, Kolkata, India
- BS - Zoology
- University of Kolkata, Kolkata, India
Research
Research interests
- Translational research
- Vascular injury in pulmonary infections
- Sepsis and acute lung injury
- Regulation of monocyte/macrophage function and host immune responses
- Cellular mechanisms and metabolic changes regulating inflammasome function
- Exosome biology and immunology
Current research
- Investigating the role of monocyte released extracellular vesicles (EVs) in endothelial dysfunction.
- Regulation of cell fate by monocyte derived EVs.
- Regulation of inflammasome by monocytes and macrophages in sepsis and ALI.
- Role of monocyte and mesenchymal cell interaction in pulmonary fibrosis.
Active funding
-
NIH R01 R01HL60947
Title: GasderminD regulation of Acute Lung Injury.
Principal Investigator: Anasuya Sarkar, PhD.
Awards and honors
- Rising Star Award, Department of Internal Medicine, Ohio State University College of Medicine, The Ohio State University. 2022
- FAME Career Development Award for Researchers, Center for faculty Mentoring and Engagement, Ohio State University College of Medicine. 2020
Professional activities
- Judge, The Ohio State University, 2011 - present
- Leukemia and Lymphoma Society - Capital City Half Marathon, 2009 - present
