Bryan Smith, PhD

About

Biography

I am Bryan R. Smith, PhD, professor in the Department of Molecular Medicine and Therapeutics. My research develops nanomaterials and nano-enabled approaches to visualize, measure and manipulate biological systems for precision diagnosis and therapy. We integrate engineering, chemistry, imaging, biology, physics, and medicine to create new approaches for molecular imaging, drug delivery, controlled therapeutic release, and immune engineering.

A major emphasis of my laboratory is advancing nano-immunoimaging and nano-immunotherapy in which we use nanoparticles to selectively target immune cells, monitor inflammation and disease processes in vivo, and deliver drugs with high precision while minimizing side effects.

Through the Translational NanoImmunoEngineering (T-NIE) Laboratory, we develop molecular imaging technologies, smart nanomaterials, and biomaterials that enable quantitative measurement of biological processes, in vivo characterization of cellular mechanical properties, real-time monitoring of in vivo drug release, and selectively-targeted therapeutic delivery platforms. Our work addresses major challenges in cancer, cardiovascular disease, diabetes, and other inflammation-associated diseases, with the goal of translating new engineering technologies into clinically impactful diagnostics and therapeutics.

Credentials

Research