Jiayi Chen, PhD
Assistant Professor
Biological Chemistry and Pharmacology
Academic information
- Department: Biological Chemistry and Pharmacology
Research interests
- Cytoskeletal Dynamics
- Structural Biology
- Biochemistry
- Posttranslational Modifications.
About
Biography
The Chen lab aims to understand the molecular mechanisms underlying cytoskeletal dynamics and how cytoskeletal remodeling impacts cell division, migration, and adhesion. We use multidisciplinary approaches, including cryo-electron microscopy and crystallography to study polymer structures during assembly, mass spectrometry and in vitro assays to elucidate the biochemical properties of polymers, and high-resolution light microscopy to characterize their dynamic properties. Our long-term goals are to understand how disease-associated mutations alter cytoskeletal dynamics and organization, and how regulation of the cytoskeletal meshwork contributes to normal physiology and human disease.
Credentials
Education
- Postdoctoral Fellowship
- National Institute of Neurological Disorder and Stroke, Bethesda, MD, United States
- PhD
- Fudan University, Shanghai, China
- BS
- Fudan University, Shanghai, China
Research
Research interests
- Cytoskeletal Dynamics
- Structural Biology
- Biochemistry
- Posttranslational Modifications.