Manjula Karpurapu
Assistant Professor
Internal Medicine
Academic information
- Department: Internal Medicine
Research interests
- Peptide inhibitors to target Calcineurin-NFATc3 signaling
- Extracellular vesicles in ALI/ARDS
- PU.1- DNA binding interactions
- Metabolites of arachidonic acid in inflammation
About
Biography
My research aims to understand the molecular mechanisms of pulmonary inflammation and how it resolves. Specifically, I investigate transcriptional gene regulation, macrophage-lung structural cell interactions, and the role of extracellular vesicle cargo in ARDS pathophysiology.
Credentials
Education
- PhD
- University of Hyderabad, Hyderabad, India
Research
Research interests
- Peptide inhibitors to target Calcineurin-NFATc3 signaling
- Extracellular vesicles in ALI/ARDS
- PU.1- DNA binding interactions
- Metabolites of arachidonic acid in inflammation
Funding
- AHA Scientist development grant (PI) 2017-2020
- NHLBI-RO1 HL137224 (Co-I) 2022-2025