Sangwoon Chung
Assistant Professor
Internal Medicine
Academic information
- Department: Internal Medicine
Research interests
- Role of macrophages in asthma pathogenesis
- Mechanism of electronic-cigarette-induced lung injury
- The role of macrophages in ARDS and lung inflammation
About
Biography
I received my undergraduate and Master of Science degree at Pusan National University in South Korea prior to obtaining a Ph.D. in Pharmaceutical Sciences from Kanazawa University in Japan. I joined Dr. Christman’s lab group at the University of Illinois at Chicago as a Postdoc Researcher, and in 2013 I moved with Dr. Christman to the Davis Heart and Lung Research Institute at the Ohio State University. Since joining The Ohio State University, I have developed expertise in many areas of pre-clinical animal models and subsequent analysis to define the role of alternatively activated macrophages in asthma pathogenesis.
Credentials
Education
- PhD
- Kanazawa University, Kanazawa, Japan
Research
Research interests
- Role of macrophages in asthma pathogenesis
- Mechanism of electronic-cigarette-induced lung injury
- The role of macrophages in ARDS and lung inflammation
Current Research
- Defining a novel therapeutic tool using optimized exosomes-cellular components that exist outside the cell-to provide pre-clinical evidence for mitigating the inflammatory asthmatic features for neutrophilic severe asthma patients.
- Sex-specific difference on mitochondrial dysfunction after Electronic-cigarette exposure that contributes to increased asthma exacerbations.
- The hypothesis that recruitment and polarization of macrophages are important in airway inflammation in order to design new and effective treatments.
Active Funding
OSU Bridge Award (PI)
The Ohio State University, Department of Internal Medicine Pilot Funding Program
Sex difference in adverse effects of electronic-cigarette (EC) with asthma
Catalyst Award (PI)
American Lung Association
Preventing neutrophilic inflammation in severe asthma by targeting ETosis
NIH R01 (Co-I)
Regulation of the Macrophage Inflammatory Phenotype in ARDS