Mora_Ana_720x720Associate Director of Lung Research DHLRI
Professor, Department of Internal Medicine Division of Pulmonary, Critical Care & Sleep Medicine

513 Davis Heart & Lung Research Institute
473 W. 12th Avenue
Columbus, OH 43210

Ana L. Mora received her MD from Universidad Nacional de Colombia Medical School in Bogota, Colombia. After Research Trainee and Research Associate in Immunology in Colombia, Dr. Mora had her postdoctoral training as a Fellow in the Department of Microbiology and Immunology at Vanderbilt University. Dr. Mora moved to Emory University in 2002 as faculty in the Division of Pulmonary, Allergy and Critical Care Medicine of the Emory University Department of Medicine, and in 2010 she joined the Division of Pulmonary, Allergy and Critical Care Medicine and the Vascular Medicine Institute at the University of Pittsburgh. From 2018 to 2021, Dr. Mora was faculty member of the Aging Institute of the University of Pittsburgh as Director of Education. Since February 2021, join the Division of Pulmonary Critical Care and Sleep Medicine at the Ohio State University as Associate Director of Lung Research.

Current Research

Dr. Mora’s research is focused in the elucidation of the pathogenic mechanisms involved in the disrepair and fibrosis in the lung and importantly, how aging-related cell perturbations contribute to this pathogenic process. Her pioneered aging studies showed that vulnerability and persistence of ER stress responses are key components of the age-related susceptibility to injury and lung fibrosis; and elucidated the novel concept that alterations in mitochondrial homeostasis have a key role in Idiopathic Pulmonary Fibrosis pathogenesis and a therapeutic target to halt the progression of the disease. Her work has been published in more than 96 peer review publications, several book chapters and editorial comments.

Research Interests

  • Aging
  • Lung Epithelial Cell Biology
  • Lung Fibrosis
  • Mitochondrial Biology
  • Metabolic adaptations
  • DNA damage

Education and Training

  • M.D., Universidad Nacional de Colombia Medical School, Bogota, Colombia
  • Immunology Fellow, Institute of Immunology, Universidad Nacional de Colombia, Santa Fe de Bogota, Colombia
  • Molecular Immunology Fellow, Vanderbilt University, Department of Microbiology and Immunology, Nashville, TN

Active Funding

  • NHLBI R01 HL149825-01 (Mora/Straub), 12/1/2019 – 11/30/2023
    “Type II Alveolar Redox Control in Fibrogenesis and Resolution”
  • NHLBI U01 HL145550 (Rojas/Mora/Finkel/Lafyatis) ,9/20/2019 – 6/30/2023
    “Mapping Age-Related Changes in the Lung”