The Ohio State University Wexner Medical CenterDepartment of internal medicine
General Internal Medicine and Geriatrics
Martha Morehouse Pavilion, suite 2400
2050 Kenny Road
Columbus
Ohio, 43221
li.561@osu.edu
614-293-8054
Within the Division of General Internal Medicine Dr. Li is currently working on a couple of research studies, with outcomes that aim to improve the quality of life of patients. One ongoing area of research is polypharmacy. Dr. Li, along with colleagues at The Ohio state university, is investigating the impact of polypharmacy, and looking to see whether its discontinuation affects the patient’s quality of life. This research is primarily taking place in the older generation.
Dr. Li is also investigating Alzheimer’s disease, with particular interest in the diagnosis and management of dementia in primary care. Such research has been funded by an Endowment fund set up in 2014 and also from donations from grateful patients and their family members.
Education and Training
Geriatrics Fellow: University of Michigan
Resident: Mount Carmel Medical Center Internal Medicine Residency
MD: Hebei Medical College
Residency: Mount Carmel Medical Center, Internal Medicine, Columbus, Ohio 2005 - 2008
Professional Awards
2010, Award for Teaching Excellence, OSU medical center, The Ohio State University
2009, "You Are Super" award, University of Michigan Health System, University of Michigan Health System
2009, "Making A Difference" Award, University of Michigan Health System, University of Michigan Health System
2001, Dean's Honor Roll, Pharmacy School, University of Kansas, University of Kansas
1999, Goetch Scholarship, University of Kansas
1997, Award for Excellence in Clinical Work, Hebei Medical College, Hebei Medical College
1995, Award for Excellence in Clinical Work, Hebei Medical College, Hebei Medical College
1995, Award for Excellence in Teaching, Hebei Medical College, Hebei Medical College
1994, Public Health Bureau Award, Hebei Medical College
1993, Award for Excellence in Clinical Work, Hebei Medical College, Hebei Medical College
Abstracts and Peer Reviewed Journal Articles
Bhaswati Bandyopadhyay, Guibin Li, Haishan Yin, Jeff Kuret, "Tau Aggregation and Toxicity in a Cell Culture Model of Tauopathy". Journal of Biological Chemistry. Vol. 282, no. 22: 16454-16464. 2007. (Published) ( IF: 5.581 ) ( Citation Count: 46 )
Seyb,Kathleen,I; Ansar,Sabah; Li,Guibin; Bean,Jennifer; Michaelis,Mary,L; Dobrowsky,Rick,T, "p35/Cyclin-dependent kinase 5 is required for protection against beta-amyloid-induced cell death but not tau phosphorylation by ceramide". JOURNAL OF MOLECULAR NEUROSCIENCE. Vol. 31, no. 1: 23-35. 2007. (Published) ( IF: 1.735 ) ( Citation Count: 2 )
Haishan Yin, Laguna KA, Guibin Li, Jeff Kuret, "Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1". Biochemistry. Vol. 45, no. 16: 5297-308. 2006. (Published) ( IF: 3.633 ) ( Citation Count: 10 )
Jeff Kuret, Carmen Chirita, Erin Congdon, Thersa Kannanayakal, Guibin Li, Mihaela Necula, Haishan Yin, Qi Zhong, "Pathways of tau fibrillization". Biochimica et Biophysica Acta. Vol. 1739, 167-178. 2005. (Published) ( IF: 2.382 ) ( Citation Count: 49 )
Jeff Kuret, Erin Congdon, Guibin Li, Haishan Yin, Xian Yu, Qi Zhong, "Evaluating triggers and enhancers of tau fibrillization". Microscopy Research and Technique. Vol. 67, 141-55. 2005. (Published) ( IF: 2.323 ) ( Citation Count: 41 )
Guibin Li, Haishan Yin, Jeff Kuret, "Casein kinase 1 delta phosphorylates tau and disrupts in binding to microtubules". Journal of Biological Chemistry. Vol. 279, 15938-45. 2004. (Published) ( IF: 6.355 ) ( Citation Count: 58 )
Guibin Li, Alexander Faibushevich, Bradon J. Turunen, Sung Ok Yoon, Gunda Georg, Mary L. Michaelis, Rick T. Dobrowsky, "Stabilization of the cyclin-dependent kinase 5 activator, p35, by paclitaxel decreases beta-amyloid toxicity in cortical neurons". Journal of Neurochemistry. Vol. 84, 347-62. 2003. (Published) ( IF: 4.825 ) ( Citation Count: 51 )
John Antonio Chavez, Trina Knotts, Li-Ping Wang, Guibin Li, Rick Dobrowsky, Gregory Florant, Scott Summers, "A role for ceramide, but not diacylglycerol, n the antagonism of insulin signal transduction by saturated fatty acids". Journal of Biological Chemistry. Vol. 278, 10297-303. 2003. (Published) ( IF: 6.482 ) ( Citation Count: 240 )