Assistant Professor
2255 Kenny Rd.
Pelotonia Research Center 4181
Columbus, OH 43210
Dr. Keiser leads preclinical research developing gene therapy approaches—including AAV, RNAi, and extracellular vesicles—for neurodegenerative diseases as well as acquired central nervous system. Her work challenges the traditionally cortico-centric view of these disorders by investigating the underappreciated roles of the cerebellum and hindbrain in disease progression and therapeutic response. She employs direct intracranial delivery to achieve region-specific modulation and novel AAV capsids engineered for optimized cellular and regional tropisms within the brain.
Research Interests
- Gene therapies for neurodegenerative diseases
- Novel AAV capsids
- Alzheimer’s Disease
- Traumatic brain injury and spinal cord injury
- Cerebellum and hindbrain implications in neurological disease
Education
PhD: University of Iowa, Graduate Program in Neuroscience
BS: University of Iowa, Integrative Physiology
Other Editorial Activities
- Ad hoc reviewer, Molecular Therapy Journals
Professional Activities
- Member, American Society for Gene and Cell Therapy
- Member, Neurological and Ophthalmological Gene and Cell Therapies Committee, American Society for Gene and Cell Therapy
- Member, Chronic Brain Injury Program (OSU)
- Member, Data Committee for Women in Medicine and Science (WIMS)
- Member, Gene Therapy Institute (OSU)
Honors and Awards
- Excellent in Research Award for Students and Fellows; American Society for Gene and Cell Therapy (2018)