Assistant Professor, Department of Otolaryngology - Head and Neck Surgery
Research Interests
- Phenotypes of chronic rhinosinusitis
- Molecular endotypes of chronic rhinosinusitis
- Nasal polyposis
- Eosinophilic disorders
Education
2012-2014 Allergy/Immunology Fellow
Wexner Medical Center at Ohio State University/Nationwide Children’s Hospital
2009-2012 Internal Medicine Residency Training Program
Ohio State University Medical Center
Internal Medicine residency completed June, 2012
2005-2009 Ohio State University College of Medicine
Doctor of Medicine Degree obtained June, 2009
2001-2005 University of Michigan
Honors Program Graduate
B.S. in Cellular and Molecular Biology
Contact Information
Email: curtis.159@osu.eduPhone: 614-366-3926
Research Projects
When a patient presents with truly asymptomatic hypereosinophilia without end organ manifestations, it is difficult to know when and if therapy should be initiated. In one study, the patients included had had asymptomatic HE for >5 years and none progressed. In a separate study, at least one progressed, although the inclusion criteria were less clear and many were treated with glucocorticoids. The goal of this study is to assess clinical signs and symptoms and objective measures to provide guidance to clinicians regarding the need for intervention in patients with asymptomatic eosinophilia.
While assessment and treatment of chronic rhinosinusitis has historically been based on clinical features, emerging data has shown that even with similar clinical presentations, patients may have distinct molecular endotypes. These endotypes have shown variable responses to medical therapy and surgical interventions, and better understanding of these groups will likely lead to better personalized care and improved outcomes to treatment. The purpose of this study is to better characterize molecular endotypes of chronic rhinosinusitis in our patient population via tissue and serologic studies.
Research Accomplishments
Shepherd MW, Curtis CD, Phillips G, Ogbogu PU. Atopic characteristics of patients with vocal cord dysfunction. Ann Allergy Asthma Immun. 2017:118(2):228-230.
Curtis CD, section editor, Asthma. In: ACAAI Review for the Allergy & Immunology Boards, Third edition.
Curtis CD, Ogbogu PU. Hypereosinophilic Syndrome. Clin Rev Allergy Immunol. 2016:50(2):240-251.
Curtis CD, Ogbogu PU. Evaluation and Differential Diagnosis of Persistent Marked Eosinophilia. Immunol Allergy Clin North Am. 2015:35(3)387-402.
Curtis CD, Fox CC. Treatment of adult hyper-IgD syndrome with canakinumab. J Allergy Clin Immunol Pract. 2015:3(5):817-818.
Curtis CD, Stukus DR, Scherzer R. Epinephrine preparedness in pediatric food allergic patients: an ideal time for change. Ann All Asthma Immunol. 2014;112(6):560-562.
Additional Information
Member of Alpha Omega Alpha Medical Honor Society