Matthew Gorr, PhD
Assistant Professor
Surgery
Academic information
- Department: Surgery
Research interests
- Pulmonary hypertension
- Cardiac remodeling
- Environmental exposures
- Fibrosis
About
Biography
My research is focused on improving patient outcomes by developing novel therapeutic strategies for right heart disease. I utilize RNA-sequencing, immunohistochemistry, molecular biology, flow cytometry and cell culture to examine and characterize the biology of the right ventricle compared to the left ventricle.
In my lab, I am testing novel drug targets on right ventricular fibrosis and function using animal models of pulmonary hypertension. Another project involves using patient-derived primary cell culture of smooth muscle cells and fibroblasts to study the expression of relevant genes in lung diseases including pulmonary hypertension, idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease. In addition, my team is studying the impact of e-cigarettes using rodent exposure paradigms, cell culture, and precision-cut lung slices.
Credentials
Education
- Postdoctoral Fellowship
- University of California San Diego, San Diego, CA, United States
- PhD - Molecular, Cellular and Developmental Biology
- The Ohio State University, Columbus, OH, United States
- MS - Biology
- University of Toledo, Toledo, OH, United States
- BS - Biology
- The Ohio State University, Columbus, OH, United States
Research
Research interests
- Pulmonary hypertension
- Cardiac remodeling
- Environmental exposures
- Fibrosis
Editorial Boards
- Journal of Molecular and Cellular Cardiology
- American Journal of Physiology – Heart and Circulatory Physiology
- Life Sciences
Current Funding
NIH R01-HL167963
Right ventricle remodeling in pulmonary hypertension