420 W. 12th Ave.
Columbus, OH 43210
614-292-4936 Alex.Samouilov@osumc.edu
Education
PhD: Leningrad Technological Institute, 1988
MS: Leningrad Technological Institute, 1982
MD: Leningrad Technological Institute, 1986
Honors
Oxygen Society Young Investigator AwardZweier JL, He GL, Samouilov A, Kuppusamy P. "EPR spectroscopy and imaging of oxygen: Applications to the gastrointestinal tract." In In Vivo EPR (ESR): Theory & Applications (Biological Magnetic Resonance). Edited by Lawrence J. Berliner. -. New-York, NY: Kluwer Academic/Plenum Publishers, January 2003
Samouilov A, Zweier JL. "Analytical implications of iron dithiocarbamates for measurement of nitric oxide." In METHODS IN ENZYMOLOGY 352: 506-522 Part A. -. Amsterdam: Elsevier, January 2002
Caia,Geroge; Sun,Ziqi; Yang,Fuchun; Petryakov,Sergey; Velayutham,Murugesan; Samouilov,Alexandre; Zweier,Jay,L. "EPR/NMR Co-imaging of In Vivo Redox Status in Mice." In FREE RADICAL BIOLOGY AND MEDICINE. (January 2009). S55-S55
S. Petryakov, A. Samouilov, M. Chzhan-Roytenberg, E. Kesselring, Z.Sun, and J.L. Zweier. "Segmente Surface CoilL Resonator for In Vivo EPR Applications at 1.1 GHz." Journal of Magnetic Resonance. (January 2009)
vanFaassen EE, Bahrami S, Feelisch M, Hogg N, Kelm M, Kim-Shapiro D, Kozlov AV, Li H, Lundberg JO, Mason R, Nohl H, Rassaf T, Samouilov A, Slama-Schwok A, Shiva S, Vanin A, Weitzberg E, Zweier J, Gladwin MT '. "Nitrite as Regulator of Hypoxic Signaling." Medicinal Research Reviews in Mammalian Physiology. (January 2009)
Alzawahra,Wael; Liu,Xiaoping; Li,Haitao; Samouilov,Alexandre; Zweier,Jay,L. "Nitrite functions as a vascular relaxing factor forming NO and activating guanylate cyclase (sGC): Role of sGG in nitrite-mediated NO formation." In CIRCULATION. (October 2007). 296-296
Samouilov,A; Woldman,Y; Khramtsov,V,V; Zweier,J. "Proton-induced nitrite penetration through phospholipid membranes." In FREE RADICAL RESEARCH. (January 2006). S160-S160
Samouilov,A; Roubaud,V; Zweier,J,L; Kuppusamy,P. "Quantification of free radical generation from kinetic analysis of EPR spin trapping." In FREE RADICAL BIOLOGY AND MEDICINE. (January 2004). S149-S149
Samouilov,A; Woldman,Y; Zweier,J; Khramtsov,V. "Nitrite penetrates through phospholipid membranes in the form of nitrous acid." In FREE RADICAL BIOLOGY AND MEDICINE. (January 2004). S100-S100
Li,H,T; Samouilov,A; Liu,X,P; Zweier,J,L. "Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction by site-specific reducing substrates under aerobic conditions: effect of oxygen pressure and pH value on nitric oxide generation." In FASEB JOURNAL. (March 2003). A511-A511
Zweier,J,L; Li,H,T; Samouilov,A; Liu,X,P. "Xanthine oxidase-catalyzed nitric oxide generation in the ischemic heart." In JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. (June 2003). A7-A7
Klee,C; Wang,X; Ren,H; Ghosh,M; Samouilov,A; Zweier,J. "Calcineurin: a protein phosphatase under the control of Ca2+ and reactive oxygen species." In JOURNAL OF NEUROCHEMISTRY. (December 2003). 14-14
Zweier,J,L; He,G,L; Samouilov,A; Kuppusamy,P. "EPR spectroscopy and imaging of oxygen: Applications to the gastrointestinal tract." OXYGEN TRANSPORT TO TISSUE XXIV. (January 2003). 123-131
Zweier,J,L; He,G,L; Samouilov,A; Kuppusamy,P. "EPR spectroscopy and imaging of oxygen: Applications to the gastrointestinal tract." Adv Exp Med Biol. (January 2003). 123-131
Samouilov,A; Valerie,R; Kuppusamy,P; Zweier,J. "A quantitative approach to EPR spin trapping." In FREE RADICAL BIOLOGY AND MEDICINE. (January 2003). S14-S14
Liu,X,P; Samouilov,A; Lancaster,J,R; Zweier,J,L. "Nitric oxide uptake by erythrocytes is limited by extracellular diffusion not membrane resistance." In FASEB JOURNAL. (March 2002). A849-A849
Li,H,T; Samouilov,A; Liu,X,P; Zweier,J,L. "Xanthine oxidase catalyzed nitrate reduction: An important nitrite and nitric oxide generation pathway during ischemia.." In CIRCULATION. (October 2001). 264-264
Rizzi,C; Souza,H,P; Samouilov,A; Kuppusamy,P; Roubaud,V; Zweier,J,L. "Spin trapping quantitative measurement of superoxide generation from NADPH cytochrome P450 reductase." In FREE RADICAL BIOLOGY AND MEDICINE. (January 2001). S25-?
DeSouza,H,P; Ziegelstein,R; Samouilov,A; Laurindo,F,RM; Zweier,J,L. "Substrate-dependent generation of superoxide and hydrogen peroxide by the vascular NAD(P)H oxidase activity." In FASEB JOURNAL. (March 2001). A1129-A1129
Li,H,T; Samouilov,A; Liu,X,P; Zweier,J,L. "Xanthine oxidase catalyzed nitrite reduction: An important nitric oxide producing pathway during ischemia." In CIRCULATION. (October 2000). 270-271
Souza,H,P; Liu,X,P; Samouilov,A; Laurindo,F,RM; Zweler,J,L. "Quantitative measurement of superoxide generated by vascular NAD(P)H oxidase." In CIRCULATION. (October 2000). 233-233
He,G,L; Shanker,R,A; Chzhan,M; Samouilov,A; Kuppusamy,P; Zweier,J,L. "Mapping of oxygen in gastrointestinal tract using electron paramagnetic resonance imaging." In FREE RADICAL BIOLOGY AND MEDICINE. (January 1998). S104-S104
Zweier,J,L; Wang,P,H; Samouilov,A; Kuppusamy,P. "Enzyme independent formation of nitric oxide is triggered during myocardial ischemia and results in post-ischemic injury." In FASEB JOURNAL. (March 1996). 1750-1750
Samouilov,A; Zweier,J,L. "Study of the kinetics of nitric oxide formation from nitrite dismutation.." In FASEB JOURNAL. (March 1996). 226-226Kuppusamy,P; Wang,P; Samouilov,A; Zweier,J,L. "Spatial mapping of nitric oxide generation in the ischemic heart using electron paramagnetic resonance imaging.." In FASEB JOURNAL. (March 1996). 225-225
Zweier,J,L; Wang,P,H; Samouilov,A; Kuppusamy,P. "Nitric oxide synthase independent nitric oxide formation occurs in the ischemic heart and causes postischemic injury." In JOURNAL OF INVESTIGATIVE MEDICINE. (March 1996). A247-A247
Wang,P,H; Samouilov,A; Kuppusamy,P; Zweier,J,L. "Quantitation of superoxide, nitric oxide, and peroxynitrite generation in the postischemic heart." In CIRCULATION. (October 1996). 2733-2733
Caia, G. L., Efimova, O. V., Velayutham, M., El-Mahdy, M. A., Abdelghany, T. M., Kesselring, E., Petryakov, S., Sun, Z. Q., Samouilov, A., Zweier, J. L.. "Organ specific mapping of in vivo redox state in control and cigarette smoke-exposed mice using EPR/NMR co-imaging." Journal Of Magnetic Resonance. Vol. 216, (March 2012.): 21-27
Sun,Ziqi; Li,Haihong; Petryakov,Sergey; Samouilov,Alex; Zweier,Jay,L. "In vivo proton electron double resonance imaging of mice With fast spin echo pulse sequence." JOURNAL OF MAGNETIC RESONANCE IMAGING. Vol. 35, no. 2. (February 2012.): 471-475
Efimova, O. V., Caia, G. L., Sun, Z., Petryakov, S., Kesselring, E., Samouilov, A., Zweier, J. L.. "Standard-based method for proton-electron double resonance imaging of oxygen." Journal of Magnetic Resonance. Vol. 212, no. 1. (January 2012.): 197-203
Efimova,Olga,V; Caia,George,L; Sun,Ziqi; Petryakov,Sergey; Kesselring,Eric; Samouilov,Alexandre; Zweier,Jay,L. "Standard-based method for proton-electron double resonance imaging of oxygen." JOURNAL OF MAGNETIC RESONANCE. Vol. 212, no. 1. (September 2011.): 197-203
Efimova,Olga,V; Sun,Ziqi; Petryakov,Sergey; Kesselring,Eric; Caia,George,L; Johnson,David; Zweier,Jay,L; Khramtsov,Valery,V; Samouilov,Alexandre. "Variable radio frequency proton-electron double-resonance imaging: Application to pH mapping of aqueous samples." JOURNAL OF MAGNETIC RESONANCE. Vol. 209, no. 2. (April 2011.): 227-232
Efimova, O. V., Sun, Z., Petryakov, S., Kesselring, E., Caia, G. L., Johnson, D., Zweier, J. L., Khramtsov, V. V., Samouilov, A.. "Variable radio frequency proton-electron double-resonance imaging: application to pH mapping of aqueous samples." Journal of Magnetic Resonance. Vol. 209, no. 2. (January 2011.): 227-32
Shet,Keerthi; Caia,George,L; Kesselring,Eric; Samouilov,Alexandre; Petryakov,Sergey; Lurie,David,J; Zweier,Jay,L. "A novel variable field system for field-cycled dynamic nuclear polarization spectroscopy." JOURNAL OF MAGNETIC RESONANCE. Vol. 205, no. 2. (August 2010.): 202-208
Petryakov,Sergey; Samouilov,Alexandre; Kesselring,Eric; Caia,George,L; Sun,Ziqi; Zweier,Jay,L. "Dual frequency resonator for 1.2 GHz EPR/16.2 MHz NMR co-imaging." JOURNAL OF MAGNETIC RESONANCE. Vol. 205, no. 1. (July 2010.): 1-8
Khramtsov,Valery,V; Caia,George,L; Shet,Keerthi; Kesselring,Eric; Petryakov,Sergey; Zweier,Jay,L; Samouilov,Alexandre. "Variable Field Proton-Electron Double-Resonance Imaging: Application to pH mapping of aqueous samples." JOURNAL OF MAGNETIC RESONANCE. Vol. 202, no. 2. (February 2010.): 267-273
Zweier,Jay,L; Li,Haitao; Samouilov,Alexandre; Liu,Xiaoping. "Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall." NITRIC OXIDE-BIOLOGY AND CHEMISTRY. Vol. 22, no. 2. (February 2010.): 83-90
Khramtsov, V. V., Caia, G. L., Shet, K., Kesselring, E., Petryakov, S., Zweier, J. L., Samouilov, A.. "Variable Field Proton-Electron Double-Resonance Imaging: Application to pH mapping of aqueous samples." Journal of Magnetic Resonance. Vol. 202, no. 2. (January 2010.): 267-73Samouilov, A., Bobko, A., Colantuano, G., Zweier, J. L.. "Accelerated Autoxidation of Myoglobin During the Onset of Ischemia." Free Radical Biology And Medicine. Vol. 49, (January 2010.): S29-S29
Petryakov, S., Samouilov, A., Kesselring, E., Caia, G. L., Sun, Z., Zweier, J. L.. "Dual frequency resonator for 1.2 GHz EPR/16.2 MHz NMR co-imaging." Journal of Magnetic Resonance. Vol. 205, no. 1. (January 2010.): 1-8
Shet, K., Caia, G. L., Kesselring, E., Samouilov, A., Petryakov, S., Lurie, D. J., Zweier, J. L.. "A novel variable field system for field-cycled dynamic nuclear polarization spectroscopy." Journal of Magnetic Resonance. Vol. 205, no. 2. (January 2010.): 202-8
Zweier, J. L., Li, H., Samouilov, A., Liu, X.. "Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall." Nitric Oxide. Vol. 22, no. 2. (January 2010.): 83-90
van Faassen, E. E., Babrami, S., Feelisch, M., Hogg, N., Kelm, M., Kim-Shapiro, D. B., Kozlov, A. V., Li, H. T., Lundberg, J. O., Mason, R., Nohl, H., Rassaf, T., Samouilov, A., Slama-Schwok, A., Shiva, S., Vanin, A. F., Weitzberg, E., Zweier, J., Gladwin, M. T.. "Nitrite as Regulator of Hypoxic Signaling in Mammalian Physiology." Medicinal Research Reviews. Vol. 29, no. 5. (September 2009.): 683-741
Petryakov,Sergey; Samouilov,Alexandre; Chzhan-Roytenberg,Michael; Kesselring,Eric; Sun,Ziqi; Zweier,Jay,L. "Segmented surface coil resonator for in vivo EPR applications at 1.1 GHz." JOURNAL OF MAGNETIC RESONANCE. Vol. 198, no. 1. (May 2009.): 8-14
Caia, G., Sun, Z. Q., Yang, F. C., Petryakov, S., Velayutham, M., Samouilov, A., Zweier, J. L.. "EPR/NMR Co-imaging of In Vivo Redox Status in Mice." Free Radical Biology And Medicine. Vol. 47, (January 2009.): S55-S55
Petryakov, S., Samouilov, A., Chzhan-Roytenberg, M., Kesselring, E., Sun, Z., Zweier, J. L.. "Segmented surface coil resonator for in vivo EPR applications at 1.1GHz." Journal of Magnetic Resonance. Vol. 198, no. 1. (January 2009.): 8-14
Alzawahra,Wael,F; Talukder,M,AHassan; Liu,Xiaoping; Samouilov,Alexandre; Zweier,Jay,L. "Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall." AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. Vol. 295, no. 2. (August 2008.): H499-H508
Alzawahra, W. F., Talukder, M. A., Liu, X., Samouilov, A., Zweier, J. L.. "Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall." American Journal of Physiology - Heart & Circulatory Physiology. Vol. 295, no. 2. (January 2008.): H499-508
Alzawahra WF, Talukder MAH , Liu XP, Samouilov A , Zweier JL. "Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall." AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. Vol. 295, no. 2. (January 2008.): 499-508
Alzawahra, W., Liu, X. P., Li, H. T., Samouilov, A., Zweier, J. L.. "Nitrite functions as a vascular relaxing factor forming NO and activating guanylate cyclase (sGC): Role of sGG in nitrite-mediated NO formation." Circulation. Vol. 116, no. 16. (October 2007.): 296-296
Petryakov,Sergey; Samouilov,Alexandre; Kesselring,Eric; Wasowicz,Tomasz; Cala,George,L; Zweier,Jay,L. "Single loop multi-gap resonator for whole body EPR imaging of mice at 1.2 GHz." JOURNAL OF MAGNETIC RESONANCE. Vol. 188, no. 1. (September 2007.): 68-73
Samouilov,Alexandre; Caia,George,L; Kesselring,Eric; Petryakov,Sergey; Wasowicz,Tornasz; Zweier,Jay,L. "Development of a hybrid EPR/NMR coimaging system." MAGNETIC RESONANCE IN MEDICINE. Vol. 58, no. 1. (July 2007.): 156-166
Samouilov,A; Woldman,Ya,Yu; Zweier,J,L; Khramtsov,V,V. "Magnetic resonance study of the transmembrane nitrite diffusion." NITRIC OXIDE-BIOLOGY AND CHEMISTRY. Vol. 16, no. 3. (May 2007.): 362-370
Samouilov A, Woldman YY, Zweier JL, Khramtsov VV. "Magnetic resonance study of the transmembrane nitrite diffusion.." Nitric Oxide. Vol. 16, no. 3. (January 2007.): 362-70
Cardounel, A. J., Cui, H., Samouilov, A., Johnson, W., Kearns, P., Tsai, A. L., Berka, V., Zweier, J. L.. "Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function." Journal of Biological Chemistry. Vol. 282, no. 2. (January 2007.): 879-87
Cardounel AJ, Cui H, Samouilov A, Johnson W, Kearns P, Tsai AL, Berka V, Zweier JL. "Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function.." J Biol Chem. Vol. 282, no. 2. (January 2007.): 879-887
Petryakov, S., Samouilov, A., Kesselring, E., Wasowicz, T., Caia, G. L., Zweier, J. L.. "Single loop multi-gap resonator for whole body EPR imaging of mice at 1.2 GHz." Journal of Magnetic Resonance. Vol. 188, no. 1. (January 2007.): 68-73
Petryakov S, Samouilov A, Kesselring E, Wasowicz T, Caia GL, Zweier JL. "Single loop multi-gap resonator for whole body EPR imaging of mice at 1.2 GHz.." J Magn Reson. Vol. 188, no. 1. (January 2007.): 68-73
Dinkova-Kostova, A. T., Cheah, J., Samouilov, A., Zweier, J. L., Bozak, R. E., Hicks, R. J., Talalay, P.. "Phenolic Michael reaction acceptors: combined direct and indirect antioxidant defenses against electrophiles and oxidants." Medicinal Chemistry. Vol. 3, no. 3. (January 2007.): 261-8
Dinkova-Kostova AT, Cheah J, Samouilov A, Zweier JL, Bozak RE, Hicks RJ, Talalay, P. "Phenolic Michael reaction acceptors: combined direct and indirect antioxidant defenses against electrophiles and oxidants.." Med Chem. Vol. 3, no. 3. (January 2007.): 261-8
Samouilov, A., Woldman, Y. Y., Zweier, J. L., Khramtsov, V. V.. "Magnetic resonance study of the transmembrane nitrite diffusion." Nitric Oxide. Vol. 16, no. 3. (January 2007.): 362-70
Samouilov A, Caia GL, Kesselring E, Petryakov S, Wasowicz T, Zweier JL. "Development of a hybrid EPR/NMR coimaging system.." Mag Reson Med. Vol. 58, no. 1. (January 2007.): 156-66
Samouilov, A., Caia, G. L., Kesselring, E., Petryakov, S., Wasowicz, T., Zweier, J. L.. "Development of a hybrid EPR/NMR coimaging system." Magnetic Resonance in Medicine. Vol. 58, no. 1. (January 2007.): 156-66
Dinkova-Kostova,A,T; Cheah,J; Samouilov,A; Zweier,J,L; Bozak,R,E; Hicks,R,J; Talalay,P. "Phenolic Michael reaction acceptors: Combined direct and indirect antioxidant Defenses against electrophiles and oxidants." MEDICINAL CHEMISTRY. Vol. 3, no. 3. (January 2007.): 261-268
Petryakov,Sergey; Samouilov,Alexandre; Roytenberg,Michael; Li,Haihong; Zweier,Jay,L. "Modified alderman-grant resonator with high-power stability for proton electron double resonance imaging." MAGNETIC RESONANCE IN MEDICINE. Vol. 56, no. 3. (September 2006.): 654-659
Samouilov, A., Woldman, Y., Khramtsov, V. V., Zweier, J.. "Proton-induced nitrite penetration through phospholipid membranes." Free Radical Research. Vol. 40, (January 2006.): S160-S160
Petryakov, S., Samouilov, A., Roytenberg, M., Li, H., Zweier, J. L.. "Modified Alderman-Grant resonator with high-power stability for proton electron double resonance imaging." Magnetic Resonance in Medicine. Vol. 56, no. 3. (January 2006.): 654-9
Samouilov,A; Roubaud,V; Kuppusamy,P; Zweier,J,L. "Kinetic analysis-based quantitation of free radical generation in EPR spin trapping." ANALYTICAL BIOCHEMISTRY. Vol. 334, no. 1. (November 2004.): 145-154
Li,H,T; Samouilov,A; Liu,X,P; Zweier,J,L. "Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 279, no. 17. (April 2004.): 16939-16946
Tiravanti,E; Samouilov,A; Zweier,J,L. "Nitrosyl-heme complexes are formed in the ischemic heart - Evidence of nitrite-derived nitric oxide formation, storage, and signaling in post-ischemic tissues." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 279, no. 12. (March 2004.): 11065-11073
Li, H., Samouilov, A., Liu, X., Zweier, J. L.. "Characterization of the effects of oxygen on xanthine oxidase-mediated nitric oxide formation." Journal of Biological Chemistry. Vol. 279, no. 17. (January 2004.): 16939-46
Samouilov, A., Woldman, Y., Zweier, J., Khramtsov, V.. "Nitrite penetrates through phospholipid membranes in the form of nitrous acid." Free Radical Biology And Medicine. Vol. 37, (January 2004.): S100-S100
Samouilov, A., Roubaud, V., Zweier, J. L., Kuppusamy, P.. "Quantification of free radical generation from kinetic analysis of EPR spin trapping." Free Radical Biology And Medicine. Vol. 36, (January 2004.): S149-S149
Samouilov, A., Roubaud, V., Kuppusamy, P., Zweier, J. L.. "Kinetic analysis-based quantitation of free radical generation in EPR spin trapping." Analytical Biochemistry. Vol. 334, no. 1. (January 2004.): 145-54
Tiravanti, E., Samouilov, A., Zweier, J. L.. "Nitrosyl-heme complexes are formed in the ischemic heart: evidence of nitrite-derived nitric oxide formation, storage, and signaling in post-ischemic tissues." Journal of Biological Chemistry. Vol. 279, no. 12. (January 2004.): 11065-73
Rizzi,C; Samouilov,A; Kutala,V,K; Parinandi,N,L; Zweier,J,L; Kuppusamy,P. "Application of a trityl-based radical probe for measuring superoxide." FREE RADICAL BIOLOGY AND MEDICINE. Vol. 35, no. 12. (December 2003.): 1608-1618
Klee, C., Wang, X., Ren, H., Ghosh, M., Samouilov, A., Zweier, J.. "Calcineurin: a protein phosphatase under the control of Ca2+ and reactive oxygen species." Journal Of Neurochemistry. Vol. 87, (December 2003.): 14-14
Zweier, J. L., Li, H. T., Samouilov, A., Liu, X. P.. "Xanthine oxidase-catalyzed nitric oxide generation in the ischemic heart." Journal Of Molecular And Cellular Cardiology. Vol. 35, no. 6. (June 2003.): A7-A7
Li, H. T., Samouilov, A., Liu, X. P., Zweier, J. L.. "Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction by site-specific reducing substrates under aerobic conditions: effect of oxygen pressure and pH value on nitric oxide generation." Faseb Journal. Vol. 17, no. 4. (March 2003.): A511-A511
Li,H,T; Samouilov,A; Liu,X,Q; Zweier,J,L. "Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: Evaluation of its role in nitrite and nitric oxide generation in anoxic tissues." BIOCHEMISTRY. Vol. 42, no. 4. (February 2003.): 1150-1159
Rizzi, C., Samouilov, A., Kutala, V. K., Parinandi, N. L., Zweier, J. L., Kuppusamy, P.. "Application of a trityl-based radical probe for measuring superoxide." Free Radical Biology & Medicine. Vol. 35, no. 12. (January 2003.): 1608-18
Samouilov, A., Valerie, R., Kuppusamy, P., Zweier, J.. "A quantitative approach to EPR spin trapping." Free Radical Biology And Medicine. Vol. 35, (January 2003.): S14-S14
Zweier, J. L., He, G., Samouilov, A., Kuppusamy, P.. "EPR spectroscopy and imaging of oxygen: applications to the gastrointestinal tract." Advances in Experimental Medicine & Biology. Vol. 530, (January 2003.): 123-31
Li, H., Samouilov, A., Liu, X., Zweier, J. L.. "Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues." Biochemistry. Vol. 42, no. 4. (January 2003.): 1150-9
Liu,X,P; Samouilov,A; Lancaster,J,R; Zweier,J,L. "Nitric oxide uptake by erythrocytes is primarily limited by extracellular diffusion not membrane resistance." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 277, no. 29. (July 2002.): 26194-26199
He,G,L; Samouilov,A; Kuppusamy,P; Zweier,J,L. "In vivo imaging of free radicals: Applications from mouse to man." MOLECULAR AND CELLULAR BIOCHEMISTRY. Vol. 234, no. 1. (May 2002.): 359-367
He,Guanglong; Samouilov,Alexandre; Kuppusamy,Periannan; Zweier,Jay,L. "In vivo imaging of free radicals: applications from mouse to man.." Molecular and cellular biochemistry. Vol. 234-235, no. 1-2. (May 2002.): 359-367
Liu, X. P., Samouilov, A., Lancaster, J. R., Zweier, J. L.. "Nitric oxide uptake by erythrocytes is limited by extracellular diffusion not membrane resistance." Faseb Journal. Vol. 16, no. 5. (March 2002.): A849-A849
Souza, H. P., Liu, X. P., Samouilov, A., Kuppusamy, P., Laurindo, F. R. M., Zweier, J. L.. "Quantitation of superoxide generation and substrate utilization by vascular NAD(P)H oxidase." American Journal Of Physiology-Heart And Circulatory Physiology. Vol. 282, no. 2. (February 2002.): H466-H474
Souza, H. P., Liu, X., Samouilov, A., Kuppusamy, P., Laurindo, F. R., Zweier, J. L.. "Quantitation of superoxide generation and substrate utilization by vascular NAD(P)H oxidase." American Journal of Physiology - Heart & Circulatory Physiology. Vol. 282, no. 2. (January 2002.): H466-74
Liu, X., Samouilov, A., Lancaster, J. R., Jr., Zweier, J. L.. "Nitric oxide uptake by erythrocytes is primarily limited by extracellular diffusion not membrane resistance." Journal of Biological Chemistry. Vol. 277, no. 29. (January 2002.): 26194-9
Samouilov, A., Zweier, J. L.. "Analytical implications of iron dithiocarbamates for measurement of nitric oxide." Methods in Enzymology. Vol. 352, (January 2002.): 506-22
Samouilov,A; Zweier,J,L. "Analytical implications of iron dithiocarbamates for measurement of nitric oxide." REDOX CELL BIOLOGY AND GENETICS, PART A. Vol. 352, (January 2002.): 506-522
He, G., Samouilov, A., Kuppusamy, P., Zweier, J. L.. "In vivo imaging of free radicals: applications from mouse to man." Molecular & Cellular Biochemistry. Vol. 234-235, no. 1-2. (January 2002.): 359-67
Li, H. T., Samouilov, A., Liu, X. P., Zweier, J. L.. "Xanthine oxidase catalyzed nitrate reduction: An important nitrite and nitric oxide generation pathway during ischemia." Circulation. Vol. 104, no. 17. (October 2001.): 264-264
Li,H,T; Samouilov,A; Liu,X,P; Zweier,J,L. "Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction - Evaluation of its role in nitric oxide generation in anoxic tissues." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 276, no. 27. (July 2001.): 24482-24489
Petryakov,S; Chzhan,M; Samouilov,A; He,G,L; Kuppusamy,P; Zweier,J,L. "A bridged loop-gap S-band surface resonator for topical EPR spectroscopy." JOURNAL OF MAGNETIC RESONANCE. Vol. 151, no. 1. (July 2001.): 124-128
He, G. L., Petryakov, S., Samouilov, A., Chzhan, M., Kuppusamy, P., Zweier, J. L.. "Development of a resonator with automatic tuning and coupling capability to minimize sample motion noise for in vivo EPR spectroscopy." Journal Of Magnetic Resonance. Vol. 149, no. 2. (April 2001.): 218-227
DeSouza, H. P., Ziegelstein, R., Samouilov, A., Laurindo, F. R. M., Zweier, J. L.. "Substrate-dependent generation of superoxide and hydrogen peroxide by the vascular NAD(P)H oxidase activity." Faseb Journal. Vol. 15, no. 5. (March 2001.): A1129-A1129
Li, H., Samouilov, A., Liu, X., Zweier, J. L.. "Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction. Evaluation of its role in nitric oxide generation in anoxic tissues." Journal of Biological Chemistry. Vol. 276, no. 27. (January 2001.): 24482-9
He, G., Samouilov, A., Kuppusamy, P., Zweier, J. L.. "In vivo EPR imaging of the distribution and metabolism of nitroxide radicals in human skin." Journal of Magnetic Resonance. Vol. 148, no. 1. (January 2001.): 155-64
He, G., Petryakov, S., Samouilov, A., Chzhan, M., Kuppusamy, P., Zweier, J. L.. "Development of a resonator with automatic tuning and coupling capability to minimize sample motion noise for in vivo EPR spectroscopy." Journal of Magnetic Resonance. Vol. 149, no. 2. (January 2001.): 218-27
Petryakov, S., Chzhan, M., Samouilov, A., He, G., Kuppusamy, P., Zweier, J. L.. "A bridged loop-gap S-band surface resonator for topical EPR spectroscopy." Journal of Magnetic Resonance. Vol. 151, no. 1. (January 2001.): 124-8
Rizzi, C., Souza, H. P., Samouilov, A., Kuppusamy, P., Roubaud, V., Zweier, J. L.. "Spin trapping quantitative measurement of superoxide generation from NADPH cytochrome P450 reductase." Free Radical Biology And Medicine. Vol. 31, (January 2001.): S25-+
He, G. L., Samouilov, A., Kuppusamy, P., Zweier, J. L.. "In vivo EPR imaging of the distribution and metabolism of nitroxide radicals in human skin." Journal Of Magnetic Resonance. Vol. 148, no. 1. (January 2001.): 155-164
Souza, H. P., Liu, X. P., Samouilov, A., Laurindo, F. R. M., Zweler, J. L.. "Quantitative measurement of superoxide generated by vascular NAD(P)H oxidase." Circulation. Vol. 102, no. 18. (October 2000.): 233-233
Li, H. T., Samouilov, A., Liu, X. P., Zweier, J. L.. "Xanthine oxidase catalyzed nitrite reduction: An important nitric oxide producing pathway during ischemia." Circulation. Vol. 102, no. 18. (October 2000.): 270-271
Vanin, A. F., Liu, X. P., Samouilov, A., Stukan, R. A., Zweier, J. L.. "Redox properties of iron-dithiocarbamates and their nitrosyl derivatives: implications for their use as traps of nitric oxide in biological systems." Biochimica Et Biophysica Acta-General Subjects. Vol. 1474, no. 3. (May 2000.): 365-377
Vanin, A. F., Liu, X., Samouilov, A., Stukan, R. A., Zweier, J. L.. "Redox properties of iron-dithiocarbamates and their nitrosyl derivatives: implications for their use as traps of nitric oxide in biological systems." Biochimica et Biophysica Acta. Vol. 1474, no. 3. (January 2000.): 365-77
Vanin, A. F., Liu, X., Samouilov, A., Stukan, R. A., Zweier, J. L.. "Redox properties of iron-dithiocarbamates and their nitrosyl derivatives: implications for their use as traps of nitric oxide in biological systems." Biochimica et Biophysica Acta. Vol. 1474, no. 3. (January 2000.): 365-77
Salvemini,D; Wang,Z,Q; Zweier,J,L; Samouilov,A; Macarthur,H; Misko,T,P; Currie,M,G; Cuzzocrea,S; Sikorski,J,A; Riley,D,P. "A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats." SCIENCE. Vol. 286, no. 5438. (October 1999.): 304-306
Zweier,J,L; Samouilov,A; Kuppusamy,P. "Non-enzymatic nitric oxide synthesis in biological systems." BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. Vol. 1411, no. 2-3. (May 1999.): 250-262
Zweier, J. L., Samouilov, A., Kuppusamy, P.. "Non-enzymatic nitric oxide synthesis in biological systems." Biochimica et Biophysica Acta. Vol. 1411, no. 2-3. (January 1999.): 250-62
Chzhan, M., Kuppusamy, P., Samouilov, A., He, G., Zweier, J. L.. "A tunable reentrant resonator with transverse orientation of electric field for in vivo EPR spectroscopy." Journal of Magnetic Resonance. Vol. 137, no. 2. (January 1999.): 373-8
Salvemini, D., Wang, Z. Q., Zweier, J. L., Samouilov, A., Macarthur, H., Misko, T. P., Currie, M. G., Cuzzocrea, S., Sikorski, J. A., Riley, D. P.. "A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats." Science. Vol. 286, no. 5438. (January 1999.): 304-6
He, G., Shankar, R. A., Chzhan, M., Samouilov, A., Kuppusamy, P., Zweier, J. L.. "Noninvasive measurement of anatomic structure and intraluminal oxygenation in the gastrointestinal tract of living mice with spatial and spectral EPR imaging." Proceedings of the National Academy of Sciences of the United States of America. Vol. 96, no. 8. (January 1999.): 4586-91
Samouilov,A; Kuppusamy,P; Zweier,J,L. "Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems." ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. Vol. 357, no. 1. (September 1998.): 1-7
Zweier,J,L; Chzhan,M; Samouilov,A; Kuppusamy,P. "Electron paramagnetic resonance imaging of the rat heart." PHYSICS IN MEDICINE AND BIOLOGY. Vol. 43, no. 7. (July 1998.): 1823-1835
Samouilov,A; Zweier,J,L. "Development of chemiluminescence-based methods for specific quantitation of nitrosylated thiols." ANALYTICAL BIOCHEMISTRY. Vol. 258, no. 2. (May 1998.): 322-330
Samouilov, A., Zweier, J. L.. "Development of chemiluminescence-based methods for specific quantitation of nitrosylated thiols." Analytical Biochemistry. Vol. 258, no. 2. (January 1998.): 322-30
He, G. L., Shanker, R. A., Chzhan, M., Samouilov, A., Kuppusamy, P., Zweier, J. L.. "Mapping of oxygen in gastrointestinal tract using electron paramagnetic resonance imaging." Free Radical Biology And Medicine. Vol. 25, (January 1998.): S104-S104
Samouilov, A., Kuppusamy, P., Zweier, J. L.. "Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems." Archives of Biochemistry & Biophysics. Vol. 357, no. 1. (January 1998.): 1-7
Zweier, J. L., Chzhan, M., Samouilov, A., Kuppusamy, P.. "Electron paramagnetic resonance imaging of the rat heart." Physics in Medicine & Biology. Vol. 43, no. 7. (January 1998.): 1823-35
Wang, P. H., Samouilov, A., Kuppusamy, P., Zweier, J. L.. "Quantitation of superoxide, nitric oxide, and peroxynitrite generation in the postischemic heart." Circulation. Vol. 94, no. 8. (October 1996.): 2733-2733
Kuppusamy,P; Wang,P,H; Samouilov,A; Zweier,J,L. "Spatial mapping of nitric oxide generation in the ischemic heart using electron paramagnetic resonance imaging." MAGNETIC RESONANCE IN MEDICINE. Vol. 36, no. 2. (August 1996.): 212-218
Zweier, J. L., Wang, P. H., Samouilov, A., Kuppusamy, P.. "Nitric oxide synthase independent nitric oxide formation occurs in the ischemic heart and causes postischemic injury." Journal Of Investigative Medicine. Vol. 44, no. 3. (March 1996.): A247-A247
Zweier, J. L., Wang, P. H., Samouilov, A., Kuppusamy, P.. "Enzyme independent formation of nitric oxide is triggered during myocardial ischemia and results in post-ischemic injury." Faseb Journal. Vol. 10, no. 3. (March 1996.): 1750-1750
Samouilov, A., Zweier, J. L.. "Study of the kinetics of nitric oxide formation from nitrite dismutation." Faseb Journal. Vol. 10, no. 3. (March 1996.): 226-226
Kuppusamy, P., Wang, P., Samouilov, A., Zweier, J. L.. "Spatial mapping of nitric oxide generation in the ischemic heart using electron paramagnetic resonance imaging." Magnetic Resonance in Medicine. Vol. 36, no. 2. (January 1996.): 212-8
Zweier,J,L; Samouilov,A; Chzhan,M. "Measurement of nitric oxide with a solid-state-char EPR probe." JOURNAL OF MAGNETIC RESONANCE SERIES B. Vol. 109, no. 3. (December 1995.): 259-263
Zweier,J,L; Wang,P,H; Samouilov,A; Kuppusamy,P. "ENZYMATIC NONENZYMATIC FORMATION OF NITRIC-OXIDE - REPLY." NATURE MEDICINE. Vol. 1, no. 11. (November 1995.): 1103-1104
Zweier, J. L., Wang, P., Samouilov, A., Kuppusamy, P.. "Enzyme-independent formation of nitric oxide in biological tissues." Nature Medicine. Vol. 1, no. 8. (January 1995.): 804-9
Kuppusamy, P., Chzhan, M., Samouilov, A., Wang, P., Zweier, J. L.. "Mapping the spin-density and lineshape distribution of free radicals using 4D spectral-spatial EPR imaging." Journal of Magnetic Resonance Series B. Vol. 107, no. 2. (January 1995.): 116-25
Zweier, J. L., Samouilov, A., Chzhan, M.. "Measurement of nitric oxide with a solid-state-char EPR probe." Journal of Magnetic Resonance Series B. Vol. 109, no. 3. (January 1995.): 259-63