• Professional Activities

  • Presentation for Girl Scouts: Science and the Future, Title Presentation: Around the world, education has no limits, Columbus, OH, present
  • Upper Arlington High School Science Fair, Columbus, OH, present
  • Chair Basic Cell and Molecular Biology Study Section, American Heart Association, Columbus, OH, 2013 - present
  • Career development panel discussion for undergraduate students in the SUCCESS program, The Ohio State University, Columbus, OH, 2015
  • Physiology and Cell Biology Research Day, The Ohio State University, Columbus, OH, 2015
    
  • Denman Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2014
  • Upper Arlington High School Science Fair, Columbus, OH, 2014
  • Building research leaders: Gender initiatives in STEM, Project CEOS and the Women’s place, Presentation: Finding your faculty career niche, The Ohio State University, Columbus, OH, 2014
  • College of Medicine Research Day, The Ohio State University, Columbus, OH, 2014
  • Davis Heart and Lung Research Institute Research Day, The Ohio State University, Columbus, OH, 2014
  • Upper Arlington High School Science Fair, Columbus, OH, 2013
  • Natural and Mathematical Sciences Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2013
  • Co-chair Basic Cell and Molecular Biology Study Section, American Heart Association, 2008 - 2013
  • The Davis Heart and Lung Research Day, The Ohio State University, Columbus, OH, 2012
  • Dr. Gustavo Amarantes-Mendes, University of São Paulo, 2012
  • Denman Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2012
  • Presentation: Opportunities for graduate education in STEM disciplines, University of Puerto Rico, Mayaguez, PR, 2012
  • National Science Foundation, Integrative Organismal Biology, 2012
  • Natural and Mathematical Sciences Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2012
  • National Institute of Health, Lung Cellular, Molecular, and Immunobiology Study Section, 2012
  • National Institute of Health, Study Section ZRG1 F09-P 20 L, 2012
  • Division of Pulmonary and Critical Care, 2006 - 2012
  • The Davis Heart and Lung Research Day, The Ohio State University, Columbus, OH, 2011
  • Dr. Johaness Tesfaigzi, Lovelace Respiratory Research Institute, Albuquerque, NM, 2011
  • Denman Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2011
  • Natural and Mathematical Sciences Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2011
  • Medical Center Research Day, The Ohio State University, Columbus, OH, 2011
  • Fourth Annual Translational to Clinical (T2C) Wound Care Conference, The Ohio State University Wexner Medical Center, Columbus, OH, 2011
  • Fifth Annual Research Day, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, 2010
  • Dr. Vincent Cryns, Northwestern University, Chicago, IL, 2010
  • Dr. David Dockrell, University of Sheffield, 2010
  • Dr. Robert Schleimer, Northwestern University, Chicago, IL, 2010
  • The 10th Anniversary Davis Heart and Lung Research Institute Research Day, The Ohio State University, Columbus, OH, 2010
  • National Institute of Health, Lung Cellular, Molecular, and Immunobiology Study Section, 2009
  • Denman Undergraduate Research Forum, The Ohio State University, Columbus, OH, 2009
  • National Science Foundation, Molecular Cellular Biology-Panel II Cellular Signaling, 2009
  • Dr. Patricia Finn, University of California, San Diego, CA, 2009
  • Davis Heart and Lung Research Institute, 2007 - 2009
  • Hatch Proposals, New Jersey Agricultural Experimental Station, Rutgers University, 2008
    
  • American Heart Association - Great Rivers Valley Area, 2007 - 2008
    
  • American Thoracic Society - Allergy and Immunology Assembly Program Organizer, 2001 - 2005

• Chapters in Books

  Doseff, A.I. and Parihar, A.. "Monocyte subsets and their role in tumor progression." In :Tumor Microenvironment and Myelomonocytic Cells. Edited by Dr. Subhra Biswas. -. ISBN: 978-953-51-0439-1: InTech, 43-62, January 2012
  
  Parihar, A., Grotewold, E., and Doseff, A.I.. "Flavonoids Dietetics: Mechanisms and Emerging Roles of Plant Nutraceuticals." In :Pigments in Fruits and Vegetables: Genomics and Dietetics. Edited by Dr. Chunxian Chen. -. N. Y.: Springer, March 2015
  

• Conferences

  Doseff, A.I., Fahy, R.J., and Wewers, M.D.. "Spontaneous monocyte apoptosis and endotoxin protection are dependent on caspase-3 and do not require caspase-1 activity." In Faseb Journal. (March 1999). A519-A519
  
  Coulter, K.R., Doseff, A.I., and Knoell, D.L.. "Lung epithelial cells constitutively express caspase activity which is augmented by IL-1 and IFN-gamma." In Am. J. Respiratory and Critical Care Medicince. (March 1999). A907-A907
  
  Marsh, C.B., Graham, M.M., Doseff, A.I., and Kelley, T.W.. "M-CSF stimulates cell survival through an Akt dependent pathway: effects on caspase activation.." In J. Investigative Medicine. (August 1999). 258A-258A
  
  Parker-Barnes, J.M., Yee, J.F., Doseff, A.I., and Wewers, M.D.. "Isolation and characterization of I kappa B zeta, a new member of the I kappa B family: Interactions with IL-1 beta." In Faseb Journal. (March 2002). A1082-A1082
  
  Knoell, D.L., Sweeney, P., Wang, Y.J., Doseff, A.I., Chaudhuri, A., and Marsh, C.B.. "FGF-7 prevents Fas-mediated apoptosis in A549 human lung epithelial cells via activation of Akt kinase." In Faseb Journal. (March 2002). A677-A677
  
  Doseff, A.I., Voss, O.H., and Gonzalez-Mejia, M.E.. "The small Heat Shock Protein 27 regulates monocyte/macrophage survival and differentiation." In Am. J. Respiratoy Critical Care Medicine. (January 2009). 1358-
  
  Henkels, K.M., Frondorf, K., Gonzalez-Mejia, M.E., Doseff, A.I., Gomez-Cambronero, J.. "IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3)." In FEBS LETTERS. (January 2011). 159-166
  
  Hostetler, G.L., Riedl, K.M., Cardenas, H., Diosa Toro, M., Schwartz, S.J., and Doseff, A.I.. "Deglycosylation of flavones enhances anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in mice." In Faseb Journal. (April 2011). 000-
  
  Tossey, J., Voss, O.H., and Doseff, A.I.. "Molecular Ffingerprinting of Hsp27 anti-apoptotic activity." In Faseb Journal. (April 2012). 000-
  
  Arango, D., Morohashi, K., Yilmaz, A., Brahimaj, B., Kuramochi, K., Grotewold, E., and Doseff, A.I.. "Identification of human-flavonoid targets using an innovative approach reveals new mechanisms Involved in their anti-inflammatory activities." In Faseb Journal. (April 2012). 000-
  

• Editorial Activities

  Present activities:
  

  • Apoptosis
  • Journal of Immunology
  • Blood
  • Journal of Biological Chemistry
  • American Journal of Respiratory and Critical Care Medicine
  • Cell Death and Differentiation
  • Stem Cell and Development
  • Biochemical Pharmacology
  • American Journal of Physiology
  • PlosOne
  • Journal of Leukocyte Biology
  • Journal of Lipid Research
  • Cell Death and Disease
  • Frontier in Biosciences, Special Issue: Mechanisms of survival and cell death in leukocytes
  • BBA-MCR (Molecular Cell Research)
  • Investigational New Drugs
  • Frontier in Biosciences
  • Cell Biology and Toxicology
  • PlosOne Genetics
  • Mutational Research
  • Molecular Nutrition and Food Research
  • PlosOne Pathogens
  • Experimental Cell Research
  • Current Nutrition and Food Science
  • Phytotheraphy Research
  • Journal Medicinal Food
  • Nature Communications
  • Journal of Medicinally Active Plants (JMAP)
  • Pharmacology and Therapeutics (Impact Factor: 10)
  • Cell Biochemistry and Biophysics

• Journal Articles

  Barneix,A,J; Doseff,A,I; RODGERS,C,O. "NITRATE REDUCTASE-ACTIVITY IN ARGENTINE WHEAT CULTIVARS." CEREAL RESEARCH COMMUNICATIONS. Vol. 16, no. 3-4. (January 1988.): 269-272
  
  Barneix, A.J., Doseff A.I., and Rodgers, C.O.. "Nitrate reductase activity In Argentine wheat cultivars." Cereal Research Communications. Vol. 16, no. 3-4. (January 1989.): 269-272
  
  Doseff, A.I., Martienssen, R., and Sundaresan, V.. "Somatatic excision of the MU1 transposable element of maize." Nucleic Acids Research. Vol. 19, no. 3. (February 1991.): 579-584
  
  Doseff, A.I.; Martienssen, R; Sundaresan, V. "Somatic excision of the Mu1 transposable element of maize.." Nucleic Acids Research. Vol. 19, no. 3. (February 1991.): 579-584
  
  Doseff, A.I. and Arndt, K.T.. "LAS1 is an essential nuclear protein invoved in cell morphogenesis and cell surface growth." Genetics. Vol. 141, no. 3. (November 1995.): 857-871
  
  Doseff, A.I.; Arndt, K.T.. "Las1 is an essential nuclear protein involved in morphogenesis and cell surface growth.." Genetics. Vol. 141, no. 3. (November 1995.): 857-871
  
  Nestler, H.P; Doseff, A. I.. "A two-dimensional, diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis technique to screen for proteases substrates in protein mixtures.." Analytical Biochemistry. Vol. 251, no. 1. (August 1997.): 122-124
  
  Nestler, H.P. and Doseff, A.I.. "A two-dimensional, diagonal sodium dodecyl sulfate-polyacrylamide gel electrophoresis technique to screen for protease substrates in protein mixtures." Analytical Biochemestry. Vol. 251, no. 1. (August 1997.): 122-125
  
  Fahy, R. J; Doseff, A. I.; Wewers, M D. "Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway which is blocked by endotoxin and is independent of caspase-1.." Journal of Immunology. Vol. 163, no. 4. (August 1999.): 1755-1762
  
  Kelley, T.W., Graham, M,M., Doseff, A.I., Pomerantz, R.W., Lau, S.M., Ostrowski, M.C., Franke, T.F., and Marsh, C.B.. "Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B." J. Biol. Chem. Vol. 274, no. 37. (September 1999.): 26393-26398
  
  Fahy, R.J.#, Doseff, A.I.#, and Wewers, M.D.. "Spontaneous human monocyte apoptosis utilizes a caspase-3-dependent pathway that is blocked by endotoxin and is independent of caspase-1." J. Immunology. Vol. 163, no. 4. (August 1999.): 1755-1762. # Indicates shared first author
  
  Kelley, T.W; Graham, M.M; Doseff, A. I.; Pommerantz, R.W; Lau, S.M; Ostrowski, M.C; Franke, T.M., Marsh, C.B;. "Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B.." The Journal of Biological Chemistry. Vol. 274, no. 37. (September 1999.): 26393-26398
  
  Kirsch, D.G., Doseff, A.I., Chau, B.N., Lim, D., Souza-Pinto, N.C., Hansford, R., Kastan, M.B Lazebnik, Y. A., and Hardwick, J.M.. "Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c.." J. Biological Chemistry. Vol. 274, no. 30. (January 1999.): 21155-21161
  
  Rovin, B.H., Wilmer, W.A., Lu, L., Doseff, A.I., Dixon, C., Kotur, M., and Hilbelink, T.. "15-Deoxy-Delta(12,14)-prostaglandin J(2) regulates mesangial cell proliferation and death." Kidney International. Vol. 61, no. 4. (April 2002.): 1293-1302
  
  Goyal, A., Wang, Y., Graham, M. M; Doseff, A.I; Bhatt, N. Y; Marsh, C.B.. "Monocyte survival factors induce Akt activation and suppress caspase-3.." American Journal of Respiratory Cell and Molecular Biology. Vol. 26, no. 2. (January 2002.): 224-230
  
  Goyal, A., Wang, Y.J., Graham, M.M., Doseff, A.I., Bhatt, N.Y., and Marsh, C.B.. "Monocyte survival factors induce Akt activation and suppress caspase-3." American J. Respiratory Cell and Molecular Biology. Vol. 26, no. 2. (February 2002.): 224-230
  
  Rovin, B.H; Wilmer, W.A; Lu, L., Doseff, A.I.; Dixon, C., Kotur, M., Hilbelink, T.. "The cyclopentenone prostaglandin 15-Deoxy-Δ12,14-prostaglandin J2 regulates mesangial cell proliferation and death.." Kidney International. Vol. 61, no. 4. (January 2002.): 1293-1302
  
  Coulter, K.R., Doseff, A.I., Sweeney, P., Wang, Y., Marsh, C.B., Wewers, M.D. and Knoell, D.L.. "Opposing effect by cytokines on Fas-mediated apoptosis in A549 lung epithelial cells.." American Journal of Respiratory Cell and Molecular Biology. Vol. 26, no. 1. (January 2002.): 58-66
  
  Doseff, A.I., Baker, J.H. Jr; Bourgeois, T.A,. Wewers, M.D.. "Interleukin-4-induced apoptosis entails caspase activation and dephosphorylation of extracellular signal-regulated kinase phosphorylation.." American Journal of Respiratory Cell and Molecular Biology. Vol. 29, no. 3 Pt 1. (January 2003.): 367-374
  
  Doseff, A.I., Baker Jr., J.H., Bourgeois, T.A. and Wewers, M.D.. "IL-4-induced apoptosis entails caspase activation and dephosphorylation of ERK." Am. J. Resp. Cell and Mol. Biology. Vol. 269, (September 2003.): 367-374
  
  Doseff,A,I; Baker,J,H; Bourgeois,T,A; WEWERS,M,D. "Interleukin-4-induced apoptosis entails caspase activation and suppression of extracellular signal-regulated kinase phosphorylation." AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. Vol. 29, no. 3. (September 2003.): 367-374
  
  Zeigler, M.M; Doseff, A.I.; Galloway, M.F; Opalek, J.M; Nowicki, P.T; Zweier, J.L; Sen, C.K; Marsh, C.B.. "The presentation of nitric oxide regulates monocyte life and death through effects on caspase-9 and caspase-3 activation.." The Journal of Biological Chemistry. Vol. 278, no. 15. (April 2003.): 12894-12900
  
  Zeigler, M.M., Doseff, A.I., Galloway, M.F., Opalek, J.M., Nowicki, P.T., Zweier, J.L., Sen, C.K., and Marsh, C.B.. "Presentation of nitric oxide regulates monocyte survival through effects on caspase-9 and caspase-3 activation." J. Biol. Chem. Vol. 278, no. 15. (April 2003.): 12894-12902
  
  Doseff, A.I.. "Apoptosis: the sculptor of development.." Stem cells and Development. Vol. 13, no. 5. (January 2004.): 473-483
  
  Wei, G., Guo, J., Doseff, A.I., Kusewitt, D.F., Man, A.K., Oshima, R.G., and Ostrowski, M.C... "Activated Ets2 is required for persistent inflammatory responses in the motheaten viable model.." J. Immunology. Vol. 173, no. 2. (January 2004.): 1374-1379
  
  Elssner, A., Doseff, A.I., Duncan, M., Kotur, M., and Wewers, M.D.. "Interleukin-16 is constitutively present in peripheral blood monocytes and spontaneously released during apoptosis.." J. Immunology. Vol. 172, no. 12. (January 2004.): 7721-7725
  
  Bao, S., Wang, Y., Sweeney, P., Chaudhuri, A., Doseff, A.I., Marsh, C.B., and Knoell, D.L.. "Keratynocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells.." American Journal of Physiology: Lung Cellular and Molecular Physiology. Vol. 288, no. 1. (January 2005.): L36-42
  
  Voss,O,H; Kim,S; WEWERS,M,D; Doseff,A,I. "Regulation of monocyte apoptosis by the protein kinase C delta-dependent phosphorylation of caspase-3." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 280, no. 17. (April 2005.): 17371-17379
  
  Voss, O.H., Kim, S., Wewers, M.D., and Doseff, A.I.. "Caspase 3 is a phosphoprotein and associates with PKCδ during spontaneous monocyte apoptosis." J. Biol. Chem. Vol. 280, no. 17. (January 2005.): 17371-17379
  
  Vargo, M.A., Voss, O.H., Poustka, F., Cardounel, A.J., Grotewold, E., and Doseff, A.I. "Apigenin-induced-apoptosis is mediated by the activation of PKCδ and caspases in leukemia cells." Biochem. Pharmacology. Vol. 72, no. 6. (January 2006.): 681-692
  
  Voss, O.H., Batra, S., Kolattukudy, S.J., Gonzalez-Mejia, M.E., Smith, J.B. and Doseff, A.I. "Heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation." J. Biol. Chem.. Vol. 282, (January 2007.): 25088-25099
  
  Voss, O.H., Batra, S., Kolattukudy, S.J., Gonzalez-Mejia, M.E., Smith, J.B., and Doseff, A.I.. "Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation." J. Biol. Chem.. Vol. 282, no. 34. (August 2007.): 25088-25099
  
  Voss, Oliver, H; Batra, Sanjay; Kolattukudy, Sunny, J; Gonzalez-Mejia, M Elba; Smith, Jeffrey, B; and Doseff, AI. "Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation." The Journal of Biological Chemistry. Vol. 282, no. 34. (January 2007.): 25088-25099
  
  Nicholas, C., Batra, S., Vargo, M.A., Voss, O.H., Gavrilin, M.A., Wewers, M.D., Guttridge, D.C., Grotewold, E., and Doseff, A.I.. "Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NFκB through the suppression of p65 phosphorylation." J. Immunology. Vol. 179, (January 2007.): 7121-7127
  
  Malavez Y., Gonzalez-Mejia, M.E., and Doseff, A.I.. "PKCδ." Atlas Genet Cytogenet Oncol Haematol. Vol. 1, (January 2008.): 10-
  
  Gonzalez-Mejia, M.E., and Doseff, A.I.. "Regulation of monocytes and macrophages cell fate." Frontiers in Bioscience. Vol. 14, (January 2009.): 2413-2431
  
  Wood, K.L., Twigg III, H.L., and Doseff, A.I.. "Dysregulation of CD8+ lymphocyte apoptosis, chronic disease, and immune regulation." Frontiers in Biosciences. Vol. 14, (January 2009.): 3771-3781
  
  Gonzalez-Mejia, M.E., Voss, O.H., Murnan, E.J., and Doseff, A.I.. "Apigenin-induced-apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of Heat Shock Protein 27." Cell Death Disease. Vol. 10, (August 2010.): 1038-
  
  Pasupuleti, N., Matsuyama, S., Voss, O., Doseff, A.I., Song, K., Danielpour, D., and Nagaraj, R.H.. "The anti-apoptotic function of human alpha A-crystallin is directly related to its chaperone activity." Cell Death and Disease. Vol. 1, (March 2010.): e31-
  
  Wood, K.L., Nunley, D.R., Moffat-Bruce, S., Pope-Harman, A., Huang, Q., Shamo, E.N., Philips, G.S., Barna, C., Batra, S., Marsh, C.B., and Doseff, A.I.. "The role of Heat Shock Protein 27 in bronchiolitis obliterans syndrome after lung transplantation." J. Heart and Lung Transplantation. Vol. 29, (January 2010.): 786-791
  
  Pasupuleti, N., Matsuyama, S., Voss, O.H., Doseff, A.I., Song, K., Danielpour, D., Nagaraj, R.. "Anti-apoptotic functions of human A-crystallin: relation to the chaperone function." Cell Death and Disease. Vol. 1, (January 2010.): e31-
  
  Parihar, A., Eubank, T. and Doseff, A.I.. "Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death." J. Innate Immunity. Vol. 2, no. 3. (January 2010.): 204-215
  
  Pasupuleti,N; Matsuyama,S; Voss,O; Doseff,A,I; Song,K; DANIELPOUR,D; Nagaraj,R,H. "The anti-apoptotic function of human alpha A-crystallin is directly related to its chaperone activity." CELL DEATH & DISEASE. Vol. 1, (March 2010.): e31-
  
  Parihar, A., Eubank, T., Doseff, A.I.. "Monocytes and Macrophages regulate immunity through dynamic networks of survival and cell death." J. Innate Immunity. Vol. 2, (January 2010.): 204-215
  
  Wood, K.L., Voss, O.H., Huang, Q., Parihar, A., Metha, N., Batra, S., and Doseff, A.I.. "The small heat shock protein 27 is a key regulator of CD8+ CD57+ lymphocyte survival." J. Immunol.. Vol. 184, (January 2010.): 5582-5588. Selected for "In this issue" special editor's commentary
  
  Abdelaziz,Dalia,HA; Gavrilin,Mikhail,A; Akhter,Anwari; Caution,Kyle; Kotrange,Sheetal; Khweek,Arwa,Abu; Abdulrahman,Basant,A; Hassan,Zeinab,A; El-Sharkawi,Fathia,Z; Bedi,Simranjit,S; Ladner,Katherine; Gonzalez-Mejia,M,Elba; Doseff,Andrea,I; Mostafa,Mahmoud; Kanneganti,Thirumala-Devi; Guttridge,Dennis; Marsh,Clay,B; Wewers,Mark,D; Amer,Amal,O. "Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.." Frontiers in microbiology. Vol. 2, (January 2011.): 1-18
  
  Abdelaziz, D.H.A., Gavrilin, M.A., Akter, A., Caution, K., Kotrange, S., Khweek, A.A., Abdulrahman, B.A., Hassan, Z.A., El-Sharkawi, F.Z., Bedi, S.S., Ladner, K., Gonzalez-Mejia, M.E., Doseff, A.I., Mostafa, M., Kanneganti, T-D., Guttridge, D., Marsh, C.B., Wewers, M.D., and Amer, A.O.. "Asc-dependent and independent mechanisms contribute to restriction of Legionella pneumophila infection in murine macrophages." Frontiers in Microbiology. Vol. 2:18, (January 2011.): 1-17
  
  Henkels, K.M., Frondorf, K., Gonzalez-Mejia, M.E., Doseff, A.I., Gomez-Cambronero, J.. "IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3)." FEBS Letters. Vol. 585, no. 1. (January 2011.): 159-166
  
  Abdelaziz,Dalia,HA; Gavrilin,Mikhail,A; Akhter,Anwari; Caution,Kyle; Kotrange,Sheetal; Khweek,Arwa,Abu; Abdulrahman,Basant,A; Hassan,Zeinab,A; El-Sharkawi,Fathia,Z; Bedi,Simranjit,S; Ladner,Katherine; Gonzalez-Mejia,M,Elba; Doseff,Andrea,I; Mostafa,Mahmoud; Kanneganti,Thirumala-Devi; Guttridge,Dennis; Marsh,Clay,B; Wewers,Mark,D; Amer,Amal,O. "Asc-dependent and independent mechanisms contribute to restriction of legionella pneumophila infection in murine macrophages.." Frontiers in microbiology. Vol. 2, (January 2011.): 3389-
  
  Abdelaziz, D.H.A., Gavrilin, M.A., Akhter, A., Caution, K., Kotrange, S., Abu Khweek, A., Abdulrahman, B.A., Hassan, Zeinab, A., El-Sharkawi, F.Z., Bedi, S.S., Ladner, K., Gonzalez-Mejia, M.E., Doseff, A.I., Mostafa, M., Kanneganti, T-D., Guttridge, D., Marsh, C.B., Wewers, M.D., and Amer, A.O.. "Asc-dependent and independent mechanisms contribute to restriction of Legionella pneumophila infection in murine macrophages." Frontiers in Microbiology. Vol. 2, (January 2011.): 1-18
  
  Arango, D., Parihar, A., Villamena, F.A., Wang, L., Freitas, M.A., Grotewold, E., and Doseff, A.I.. "Apigenin induces DNA damage through the PKCδ dependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair." Biochem. Pharmacol.. Vol. 4, (January 2012.): 1571-1580
  
  Das, A., Gopalakrishnan, B., Voss, O.H., Doseff, A.I., and Villamena, F.A.. "Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling." Biochem. Pharmacol. Vol. 84, no. 4. (August 2012.): 486-497
  
  Akhter, A., Caution, K., Khweek, A.A., Tazi, M., Abdulrahman, B.A, Abdelaziz, D.H.A., Voss, O.H., Doseff, A.I., Hassan, H. Azad, A.K., Schlesinger, L.S., Wewers, M.D., Gavrilin, M.A., and Amer, A.O.. "Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization." Immunity. Vol. 37, no. 1. (July 2012.): 35-47
  
  Hostetler, G. Riedl, K., Cardenas, H., Diosa-Toro, M., Arango, D., Schwartz, S., and Doseff, A.I.. "Flavone deglycosylation increases their anti-inflammatory activity and absorption." Mol. Nutrit. Food Res.. Vol. 56, no. 4. (April 2012.): 558-569
  
  Naomi, R.B., Wang, B., Voss, O., Doseff, A.I., Santhoshkumar, P. and Nagaraj, R.H.. "Chaperone peptides of a-crystallin inhibit epithelial cell apoptosis, protein insolubilization and opacification in experimental cataracts." J. Biol. Chem. Vol. 288, (January 2013.): 13022-13035
  
  Duarte, S., Arango, D., Yasmeen, R. Parihar, A., Hamel, P., and Doseff, A.I.. "Apigenin protects endothelial cells of LPS-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function." International J. Molecular Sciences. Vol. 14, (January 2013.): 17664-17679. #Indicates shared first authorship
  
  Arango, D., Morahashi, K., Yilmaz, A., Kuramichi, K., Parihar, A., Brahimaj, B., Grotewold, E., and Doseff, A.I.. "Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets." Proc. Natl. Acad. Sci. USA. Vol. 10, (May 2013.): 213-2162
  
  Casas, M.I., Duarte, S.M., Doseff, A.I.*, and Grotewold, E*.. "Flavone-rich maize: an opportunity to improve the nutritional value of an important commodity crop." Frontiers in Plant Sciences. Vol. 5, (September 2014.): 1-11. * Incates co
  
  Lakshmanan, A., Doseff, A.I., Ringel, M.D., Saji, M., Roussel, B., Zhang, X. and Jhiang, S.M.. "Apigenin in combination with Akt inhibition significantly enhances thyrotropin-stimulated readioiodide accumulation in thyroid cells." Thyroid. Vol. 24, (October 2014.): 878-887
  
  Burdo, B., Gray, J., Goetting-Minesky, M.P., Wittler, B., Hunt, M., Li, T., Velliquette, D., Thomas, J., Gentzel, I., dos antos Brito, M., Mejia-Guerra, M.K., Connolly, L.N., Qaisi, D., Li, W., Casas, M.I., Doseff, A.I.,and Grotewold, E.. "The maize TFome - development of a transcription factor open reading frame collection for functional genomics." Plant Journal. Vol. 80, no. 2. (October 2014.): 356-366
  
  Ouma, W.,Z., Mejia-Guerra, M.,K., Yilmaz, A., Pareja-Tobes, P., Li, W., Doseff, A.I., and Grotewold, E.. "Important biological information uncovered in previously unaligned reads from chromatin immunoprecipitation experiments (ChIP-Seq)." Scientific Reports. Vol. 5, (March 2015.): 8635-
  
  Malavez, Y., Voss, O., Parihar, A., Gonzalez-Mejia, M.E. and Doseff, A.I.. "Distinct contribution of PKCδ and PKCe in the lifespan and immune response of human blood monocyte subpopulations." Immunology. Vol. 144, no. 4. (April 2015.): 611-620
  
  Arango, D., Diosa-Toro, M., Rojas-Hernandez, L.S., Cooperstone, J.L., Schwartz, S., Mo, X., Jiang, J., Schmittgen, T., Doseff, A.I. "Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation." Mol. Nutrit. Food Res.. Vol. 59, (January 2015.): 763-772
  
  Gray, J., Burdo, B., Goetting-Minesky, M.P., Wittler, B., Hunt, M., Li, T., Velliquette, D., Thomas, J., Key, K., Gentzel, I., dos Santos Brito, M., Mejia-Guerra, M.K., Connolly, L.N., Qaisi, D., Li, W., Casas, M.I., Doseff, A.I. Grotewold, E.. "Protocol for the generation of a transcription factor open reading frame collection (TFome)." BioProtocols. Vol. 5 (15), (July 2015.): e:1547-
  
  Parihar, A., Duarte, S., and Doseff, A.I.. "The saga of food supplements: safety and missing knowldege." J. Medical Active Plants. Vol. 2, (August 2015.): 12-
  
  Parihar, A., Duarte, S. and Doseff, A.I.. "The saga of food supplements: safety and missimg knowledge." J. Med. Active Plants
  
  Arango, D., Morahashi, K., Yilmaz, A., Kuramichi, K., Parihar, A., Brahimaj, B., Grotewold, E., and Doseff, A.I.. "Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets." Proc. Natl. Acad. Sci. USA
  
  Ouma, W.Z.. "Impotant biological information uncovered in previously unaligned reads from chromatin immunoprecipitation experimets (Chip-Seq)." Scientofoc Reports
  
  Gray, J., Burdo, B., Goetting-Minesky, M. P., Wittler, B., Hunt, M., Li, T., Velliquette, D., Thomas, J., Key, K., Gentzel, I., dos Santos Brito, M., Mejía-Guerra, M.K., Connolly, L. N., Qaisi, D., Li, W., Casas, M. I., Doseff, A.I., and Grotewold, E.. "Protocol for the Generation of a Transcription Factor Open Reading Frame Collection (TFome).." BioProtocols
  

• Inventions and Patents

  Doseff, A.I.; Wood, K.. Co-Inventor. "The small Heat shock protein 27 (Hsp27) is a marker for cellular life span." filed 2006
  
  Doseff, A.I.: Swartz, Stephen; Hostetler, Gregory; Riedl, Ken; Cardenas, Horacio. Co-Inventor. "Processes for improving absorption and anti-inflammatory activity of dietary flavones." filed 2011
  
  Doseff, A.I.; Grotewold E.. Co-Inventor. "Inhibition of monocyte survival, differentiation or proliferation." filed 2005, (patent pending), and Application No. 60/684,655
  

• Poster Presentations 129 since the last promotion from a total of 200

  2015:

  • Yang, F. Li, W., Mukundi, E., Gray, J., Doseff, A.I. and Grotewold, E. Metabolic engineering of &emspmaize phenolics. (July 19-24). Gordon Conference-Plant Metabolic Engineering. Waterville &emspValley, N.H
  
  
  • Pereira, M.S.F., Arango, D., Duarte, S., Nagarajan, P., Eubank, T. and Doseff, A.I. Dietary anti-cancer apigenin delays tumor development and blocks metastasis by reducing TAMs and myeloid suppressor cells through NF-κB-inactivation. (June 4-6). Great Lakes Breast Cancer Symposium. Cleveland, OH
  
  
  • Arango, D. Mejia-Guerra, K., Mukundi, E., Eubank, T.D., Padilla-Obregon, F., Grotewold, E and Doseff, A.I. (Poster, May 27). Genome-wide effects on alternative splicing networks by dietary flavonoids restore normal RNA-signatures contributing to halt breast cancer progression. Interdisciplinary Graduate Program Symposium (May 27th). The Ohio State University, Columbus, OH
  
  
  • Alers Velazquez, R.M., Li, W., Valentin Morales, J., Prada Salcedo, L.D., Gray, J., Grotewold, E., and Doseff, A.I. (Poster, March 21-22, Awarded best poster). Characterization of PALs transcriptional regulatory network in maize. ASPB Midwestern Conference. St. Louis. MI
  
  
  • Doseff, A.I., Arango, D., Mejia-Guerra, K., Mukundi, E., Eubank, T.D., Padilla-Obregon, F., and Grotewold, E. (Poster, Jan 28-Feb 1). Genome-wide effects on alternative splicing networks by dietary flavonoids restore normal RNA-signatures contributing to halt breast cancer tumor progression and metastasis. Systems Biology, Global Regulation of Gene Expression. Cold Spring Harbor Laboratory meeting, Puerto Rico
  
  
  • Li, W., Yang, F.,Mejia-Guerra, K., Mukundi, E., Morales, J.V., Prada, L.D., Gray, J., Doseff, A.I. and Grotewold, E. (Poster, March 12-15). Transcription regulatory network controlling phenolic biosynthesis in maize factor-centered approaches reveal emerging properties of plant gene regulatory networks. 57th Annual Maize Genetics Conference St. Charles, Illinois
  
  
  • Gray, J., Goetting-Minesky, M.P., Li, T., Velliquette, D., Thomas, J., Burdo, B., Wittler, B., Hunt, M., Gentzel, I., Michael dos Santos Brito, Maria Katherine Mejía-Guerra, Layne N. Connolly, Dalya Qaisi, Casas, M.I., Doseff, A.I. and Grotewold, E. (Poster, March 12-15). The maize TFome development of a transcription factor open reading frame collection for functional genomics. 57th Annual Maize Genetics Conference St. Charles, Illinois
  
  
  • Shao, Q., Arango, D., Duarte, S., and Doseff, A.I. Molecular mechanisms of dietary compounds in leukemia and their roles in alternative splicing. (Poster, March 6). Natural and Mathematical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Grotewold, E, Morohashi, K., Li, W., Yang, F., Mejia-Guerra, K., Gray, J., and Doseff, A.I. (Poster, Jan 28-Feb 1). Gene- and transcription factor-centered approaches reveal emerging properties of plant gene regulatory networks. Systems Biology, Global Regulation of Gene Expression. Cold Spring Harbor Laboratory meeting, Puerto Rico

  2014:

  • Yang, F., Li, W., Doseff, A.I., and Grotewold, E. (Awarded 2nd Best Poster). The 8th Tripartite Workshop, Rutgers University, University of São Paulo, Brazil, and The Ohio State University. For sustainable technology innovations: integrating biology and chemistry for energy, food security and medicine. Rutgers, New Jersey. (Poster-Nov. 14-17)
  
  
  • LI, W., Mejia-Guerra, M.K., Galeanao, N.F., Vidal, M., Grotewold, E., and Doseff, A.I. Genome-wide architecture of transcriptional start sites defined by CAP Analysis of Gene Expression (CAGE) reveals distinct features and evolutionary conservations of genomes. (Poster-October 5). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Nagarajan, P., Duarte, S., Merchand, G., Rojas, L., Eubank, T. and Doseff, A.I. Immune-modulatory and anti-proliferative activities of dietary apigenin act in concert to delay breast cancer progression. (Poster-October 5). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Duarte, S., Arango, D., Taitano, D., Bao, S., Julian, M.W., Crouser, E., Hollyfield, J., Exline, M., Sarkar A., Wewers, M.D., Knoell, D.L., and Doseff, A.I. Anti-inflammatory mechanisms of dietary apigenin: alternative approaches for clinical interventions. (Poster-October 5). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Nardone-White, D., Arango, Dand Doseff, A.I. (Poster November 12-15). Identification of binding sites between the dietary anticancer compound apigenin and the RNA-binding protein hnRNPA2. Annual Biomedical Research Conference for Minority Students. San Antonio, Texas
  
  
  • Taitano, D., Arango, D. and Doseff, A.I. (Poster July 31). Immunomodulatory mechanisms of the dietary flavonoid apigenin. SUCCESS. College of Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Nardone-White, D., Arango, D, and Doseff, A.I. (Poster July 31). Identification of binding sites between the dietary anticancer compound apigenin and the RNA-binding protein hnRNPA2. Molecular Genetics, REU. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Duarte, S., Mejia-Guerra, K., Padilla-Obregon, F., Morohashi, K., Eubank, T., Grotewold, E. and Doseff, A.I. (Poster April 10). Transcriptome analyses in concert with animal models reveal the anti-carcinogenic of the dietary flavonoid apigenin in breast cancer. The 13th Trainee Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Mejia-Guerra, K., Kuramochi, K., Parihar, P., Brahimaj, B., Grotewold, E. and Doseff, A.I. (Poster February 23-28). PD-Seq, a novel small-molecule target identification approach, reveals new mechanisms responsible for the anti-inflammatory and anti-carcinogenic activities of dietary flavonoids. Keystone Meeting: The NF-kB system in health and disease. Keystone Colorado
  
  
  • Lin, J., Arango, D., and Doseff, A.I. (Poster March 26). Identification of apigenin binding sites on hnRNPA2, a RNA-binding protein overexpressed in cancer and inflammatory diseases. Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Li, W., Burdo, B., Valentin Morales, J., Prada Salcedo, L. D., Gray, J., Grotewold, E. and Doseff, A.I. (Poster March 22-23). Identification of Transcriptional Regulatory Networks Controlling Flavonoid Biosynthesis Pathway in Maize. ASPB (American Society of Plant Biology) Columbus, Ohio
  
  
  • Valentin Morales, J., Li, W., Prada Salcedo, L. D., Burdo, B., Gray, J., Grotewold, E. and Doseff, A.I. (Poster March 22-23). Identification of the transcriptional regulation that controls phenylalanine ammonia lyase (PAL) family in Maize. ASPB (American Society of Plant Biology) Columbus, Ohio
  
  
  • Burdo, B., Goetting-Minesky, M.P., Li, T., Velliquette, D., Hunt, M., Wittler, B., Gentzel, I., Gilreath, E.R., Dajnowicz, S., Abdollahzadeh, A., Thomas, J., Qaisi, D., Connolly, L., Indurti, A., Key, K., Podolski, R., Mills, M., Carstens, J., Belesky, K., Kusayanagi, T., Casas, M.I., Kataka, E., Morohashi, K., Andrade, T., Mejía-Guerra, K., Reed, A., Machemer-Noonan, K., Mukundi, E., Yu, H-D., Santos, F., Santos Brito, M., Kayanja, G., Engelmeier, J., McFarland, F., Scott, M., Campbell, J., Galeano, F., Li, W., Doseff, A.I., Gray, J., and Grotewold, E. (Poster March 22-23). The First Release of the Maize Transcription Factor ORFeome Collection. ASPB (American Society of Plant Biology). Columbus, Ohio
  
  
  • San Miguel, S., Arango, D., Parihar, A., Hamel, P., Yasmeen, R., and Doseff, A.I. (Poster March 21). Apigenin prevents LPS-induced ROS production, apoptosis and cardiac dysfunction by protecting mitochondrial functions. The 11th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio
  
  
  • Doseff, A.I. (Poster February 28). Cell Death Networks: Targeting Complex Molecular Interactions to End Cancer. Comprehensive Cancer Center Annual Meeting. The Ohio State University, Columbus, Ohio

  2013:
  

  • Doseff, A.I., Arango, D., Mejia-Guerra, K., Restrepo, D., Morohashi, K., Yilmaz, A., Kuramochi, K., Parihar, P., Brahimaj, B., and Grotewold, E. (Poster July 7-12). Identification of human targets of the dietary flavone apigenin reveals novel aspects of the anti-carcinogenic and anti-inflammatory mechanisms of phytochemicals. Gordon Conference-Plant Metabolic Engineering. Waterville Valley, N.H
  
  
  • Brito, M.S, Vicentini, R., Kiyota, E., Creste, S., Landell, M.G.A., Santos, F.C., Doseff, A.I., Gray, J., Mazzafera, P., and Grotewold, E. (Poster July 7-12) Identification of target genes regulated by the shine transcription factor in monocot plants using CHIP-Seq. Gordon Conference-Plant Metabolic Engineering. Waterville Valley, N.H
  
  
  • Matos-Nieves, A., Voss, O.H., and Doseff, A.I. (Poster, July 30). Regulation of caspase-3 by the anti-apoptotic proteins XIAP and Hsp27. SROP. The Ohio State University, Columbus, Ohio
  
  
  • Valdez, S., Arango, D., and Doseff, A.I. (Poster, August 1). Mechanisms of breast cancer chemosensitization by dietary compounds. SUCCESS program. The Ohio State University, Columbus, Ohio
  
  
  • Harder, M., Voss, O.H., and Doseff, A.I. (Poster, August 1). Using the yeast two-hybrid system to determine caspase-3 prodomain interaction with hsp27. REU-Molecular Genetics/Biochemistry. The Ohio State University, Columbus, Ohio
  
  
  • Li, W., Carstens,J., Mejía-Guerra, M.J., Morohashi, K., Gray, J., Grotewold, E., and Doseff, A.I. (Poster- March 14-17). The identification of regulatory networks that control phenolic biosynthesis in maize. 55th Annual Maize Genetics Conference. St. Charles, Illinois
  
  
  • Gray, J., Doseff, A.I. and Grotewold, E. (Poster- March 14-17). Approaches to identify gene regulatory networks in grasses. 55th Annual Maize Genetics Conference. St. Charles, Illinois
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Brahimaj, B., Kuramochi, K., Parihar, A., Brahimaj, B., Mejia-Guerra, K., Restrepo, D., Grotewold, E. and Doseff, A.I. (Poster-March 26). Target Identification of Dietary Flavonoids Revels Novel Mechanisms Involved in Their Anti-Carcinogenic Activity. The 10th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Brahimaj, B., Kuramochi, K., Parihar, A., Grotewold, E. and Doseff, A.I. (Poster-April 11- Awarded 1nd place graduate student category). The 12th Annual Ohio State University Medical Center and Graduate and Postgraduate Trainee Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H., Tossey, J., and Doseff, A.I. Anti-apoptotic proteins: essential regulators of monocyte to macrophage life span and differentiation. (Poster-April 11- Awarded 1nd place post-doc category). The 12th Annual Ohio State University Medical Center and Graduate and Postgraduate Trainee Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Tossey, J.C., Voss, O., and Doseff, A.I. The role of apigenin and Hsp27 in NSCLC apoptosis. (Poster-April). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Tossey, J.C., Voss, O., and Doseff, A.I. The role of apigenin and Hsp27 in NSCLC apoptosis. (Poster-April, Awarded honor category). Natural and Mathematical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • San Miguel, S., Parihar, A., Yasmeen, R., Arango, D., and Doseff, A.I. (Poster-April 11). Mechanisms and functional significance of bioactive food components in mitochondrial dysfunction: potential new translational approaches in inflammation-induced metabolic disorders. The 12th Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, Ohio
  
  

  2012:
  

  • Tossey, J.C., Voss, O., and Doseff, A.I. The role of apigenin and Hsp27 in NSCLC apoptosis. (Poster-October 11). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H., Tossey, J., and Doseff, A.I. (Poster-October 11). Anti-apoptotic proteins: essential regulators of monocyte to macrophage life span and differentiation. Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Brahimaj, B., Kuramochi, K. Grotewold, E. and Doseff, A.I. Identification of human-flavonoid targets using an innovative approach reveals new mechanisms involved in their anti-inflammatory activities (Selected Oral Presentation April 21-25). Experimental Biology, San Diego, CA
  
  
  • Tossey, J.C., Voss, O., and Doseff, A.I. Molecular Fingerprinting of Hsp27 Anti-Apoptotic Activity. (Poster-April 21-25). Experimental Biology, San Diego, CA
  
  
  • San Miguel, S., Pineda, C., Arango, D., and Doseff, A.I. Effect of apigenin on metabolic dysfunction in adipose tissue. (Poster-May 31. Awarded best poster) The 9th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Diosa-Toro, M., Hostetler, G., Schwartz, S.J., Hei, W., Guttridge, D., Kuramochi, K. Grotewold, E. and Doseff, A.I. Target identification and regulation of innate immunity by the dietary flavonoid apigenin. (Poster April 27) PHPID. Annual Scientific Meeting. The Ohio State University, Columbus, Ohio
  
  
  • Tossey, J., Voss, O.H., and Doseff, A.I. Molecular Identification of Hsp27 Anti-Apoptotic Activity. (Poster Awarded 2nd place). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H., Tossey, J., and Doseff, A.I. (Poster-April 18). Role of anti-apoptotic proteins in monocyte to macrophage life span and differentiation. The 11th Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, OH
  
  
  • Pineda, C., Parihar, A., Arango, D., and Doseff, A.I. Effect of apigenin on metabolic dysfunction in adipose tissue. (Poster March 8) 14th OSU-Comprehensive Cancer Center Annual Scientific Meeting. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Brahimaj, B., Kuramochi, K. Grotewold, E. and Doseff, A.I. Target identification and anti-carcinogenic mechanisms of dietary flavonoids. (Poster March 8) 14th OSU-Comprehensive Cancer Center Annual Scientific Meeting, The Ohio State University, Columbus, Ohio

  2011:

  • Arango, D., Parihar, A., and Doseff, A.I. The role of plant small metabolite in the regulation of adipocytokine secretion and hypertrophy. (Poster-October 11). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Kamran, H., and Doseff, A.I. PKCδ regulates cell death and survival through phosphorylation of caspase-3. (Poster-October 11). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K.,Yilmaz, A., Guttridge, D.C., Hei, W., Kuramochi, K., Grotewold, E., and Doseff, A.I. Innovative approach towards understanding the anti-inflammatory mechanisms of the flavonoid apigenin. (Poster-October 11, Awarded 2nd place graduate student category). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H., Tossey, J., and Doseff, A.I. Role of Hsp27 in monocyte to macrophage life span and differentiation. (Poster-October 11, Awarded 1st place postdoc category). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Tossey, J., Voss, O.H., and Doseff, A.I. Molecular fingerprinting of Hsp27-anti-apoptotic activity. (Poster-October 11, Awarded 2nd place undergraduate student category Best Poster). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  • Doseff, A.I. Morohashi, K., Arango, D., Yilmaz, A., Kuramochi, K., Brahimaj, B., and Grotewold, E. PD-Seq: Coupling phage-display with next-generation sequencing towards the identification of human cellular targets of the flavonoid apigenin and development of flavonoids nanosensors. (Oral Presentation July 24-29). Gordon Conference-Plant Metabolic Engineering. Waterville Valley, N.H
  
  
  • Hostetler, G., Riedl, K., Cardenas, H., Diosa-Toro, M. Schwartz, S. and Doseff, A.I. Deglycosylation of flavones enhances anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in mice. The 8th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, OH. (Selected oral Presentation)
  
  
  • Brahimaj, B., Arango, D., and Doseff, A.I. Molecular mechanisms of anti-carcinogenic flavonoids. (Poster-May11, Awarded Best Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Tossey, J., Voss, O.H., and Doseff, A.I. Molecular identification of Hsp2-anti-apoptotic activity. (Poster-May 11). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Brahimaj, B., Arango, D., and Doseff, A.I. Molecular mechanisms of anti-carcinogenic flavonoids. (Poster-April 8-9). Natural and Mathematical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio 
  
  
  • Tossey, J., Voss, O.H., and Doseff, A.I. Molecular identification of Hsp2-anti-apoptotic activity. (Poster-April 29. Awarded Best Poster). Natural and Mathematical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Hostetler, G., Riedl, K., Cardenas, H., Diosa-Toro, M., Schwartz, S., and Doseff, A.I. Deglycosilation of flavones enhances anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in mice. (Poster-April 9-14; Selected oral presentation). Experimental Biology, Washington, DC
  
  
  • Arango, D., Morohashi, K.,Yilmaz, A., Brahimaj, B., Kuramochi, K., Grotewold, E., and Doseff, A.I. (Poster). Innovative approach towards anti-inflammatory apigenin target identification. (Poster-April 8-9). 4th Annual Translational to Clinical (T2C) Wound Care Conference. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H. and Doseff, A.I. The cellular fate of monocytes and macrophages is regulated by Hsp27. (Poster-April 8-9). 4th Annual Translational to Clinical (T2C) Wound Care Conference. The Ohio State University, Columbus, Ohio
  
  
  • Brahimaj, B., Arango, D., Morohashi, K., Grotewold, E., and Doseff, A.I. (Poster-April 8-9). Molecular biosensor of flavonoids involved in regulation of inflammation. (Poster-April 8-9). 4th Annual Translational to Clinical (T2C) Wound Care Conference. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H. and Doseff, A.I. Hsp27 determines the cellular life span of monocytes and macrophages. (Poster-April 7). The 10th Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, OH
  
  
  • Arango, D., Morohashi, K.,Yilmaz, A., Brahimaj, B., Kuramochi, K., Grotewold, E., and Doseff, A.I. Innovative approach towards bioactive anti-carcinogenic flavonoid target identification and development of biological nanosensors. (Poster-April 7). The 10th Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, OH
  
  
  • Arango, D., Morohashi, K.,Yilmaz, A., Brahimaj, B., Kuramochi, K., Grotewold, E., and Doseff, A.I. (Poster). Innovative approach towards bioactive anti-carcinogenic flavonoid target identification and development of biological nanosensors. (Poster). 13th OSU-Comprehensive Cancer Center Annual Scientific Meeting. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Federico, M.B., Kamran, H., and Doseff, A.I. PKCδ-dependent phosphorylation of caspase-3 modulates its enzymatic activity and cell death. (Poster). 13th OSU-Comprehensive Cancer Center Annual Scientific Meeting. The Ohio State University, Columbus, Ohio
  
  
  • Hostetler, G., Riedl, K., Cardenas, H., Diosa-Toro, M., Schwartz, S., and Doseff, A.I. Deglycosilation of flavones enhances anti-inflammatory activity of food extracst in vitro and absorption of dietary flavones from celery in mice. (Poster). 13th OSU-Comprehensive Cancer Center Annual Scientific Meeting. The Ohio State University, Columbus, Ohio

  2010:

  • Cardenas, H., Nicholas, C., Nishijima, Y., Nuovo, J., and Doseff A.I. The anti-inflammatory flavonoid apigenin reduces mortality in a mouse model of acute inflammation by inhibiting lung neutrophil infiltration and reducing MIP-2 chemokine expression. (Poster, awarded 1st place). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H. and Doseff, A.I. Monocytes and macrophages life span is regulated by the association of caspase-3 with Hsp27. (Poster, awarded 1st place). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Voss, O.H., and Doseff, A.I. Phosphorylation of Hsp27 reduces its association with caspase-3 inducing monocyte apoptosis. (Poster). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Grotewold, E. and Doseff, A.I. Target identification of the flavonoid apigenin: implications for its anti-inflammatory activity. (Poster). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Hostetler, G., Riedl, K., Cardenas, H., Schwartz, S., and Doseff, A.I. Anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in mice. (Poster). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Federico, M.B., Kamran, H., Brahimaj, B., and Doseff, A.I. PKCδ phosphorylation of caspase-3 promotes apoptosis through a complex regulatory network. (Poster). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio.
  
  
  • Cardenas, H., Nicholas, C., Nishijima, Y., Nuovo, J., and Doseff A.I. Protective effect of apigenin against mortality induced by acute inflammation in mice is associated with reducition of MIP-2 chemokine expression and lung neutrophil infiltration. (Poster). 5th Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, OH
  
  
  • Voss, O.H., Parihar, A., Huang, Q., Wood, K., and Doseff, A.I. Hsp27 determines cell fate of cell cells from the innate and adaptive immune system by regulating the activation of caspase-3. (Poster, 1st place). Fifth Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine.The Ohio State University, Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Voss, O.H., and Doseff, A.I. Phosphorylation of Hsp27 reduces its association with caspase-3 inducing monocyte apoptosis. (Poster-1st place). Fifth Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Diosa-Toro, M., Arango, D., Hostetler, G., Schwartz, S., and Doseff, A.I. Celery extracts induce in vitro inhibition of NF-kB activity and TNF production in LPS-stimulated macrophages. (Poster). 5th Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Yilmaz, A., Grotewold, E. and Doseff, A.I. Anti-inflammatory mechanism of the flavonoid apigenin. (Poster). 5th Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Hostetler, G., Riedl, K., Cardenas, H., Schwartz, S., and Doseff, A.I. Anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in mice. (Poster). Fifth Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Federico, M.B., Kamran, H., Brahimaj, B., and Doseff, A.I. Phosphorylation of caspase-3 regulates apoptosis through a complex regulatory network. (Poster). Fifth Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Hernandez, J. and Doseff, A.I. Mapping the heat shock protein 27 peptide motif responsible for the inhibition of caspase-3 apoptotic activity. (Poster). 24th Annual Summer Research Opportunities Program (SROP) Conference. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Wang, L., Heine, G., Freitas, M. A., Grotewold, E. and Doseff, A.I. Anti-carcinogenic mechanisms of the plant flavonoid apigenin. (Poster, 1st place). The 7th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio
  
  
  • Hostetler, G., Riedl, K., Cardenas, H., Doseff, A.I. and Schwartz, S. Anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in a mouse model. The 7th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y., and Doseff, A.I. Role of PKCδ dependent phosphorylation of caspase-3 on programmed cell death. (Selected Plenary talk, 1st place). The Interdisciplinary Graduate Programs Symposium in the Molecular Life Sciences (MCDB, OSBP, and Biophysics). The Ohio State University, Columbus, Ohio
  
  
  • Kamran, H., Malavez, Y., Voss, O.H., and Doseff, A.I. Molecular mechanisms of caspase-dependent apoptosis. (Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Brahimaj, B., Malavez, Y., and Doseff, A.I. Molecular mechanisms of caspase-3-PKCδ-dependent phosphorylation in apoptosis. (Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Kamran, H., Malavez, Y., Voss, O.H., and Doseff, A.I. Molecular mechanisms of caspase-dependent apoptosis. (Poster). Biological, Mathematical, and Physical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Brahimaj, B., Malavez, Y., and Doseff, A.I. Molecular mechanisms of caspase-3-PKCδ-dependent phosphorylation in apoptosis. (Poster). Biological, Mathematical, and Physical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Kamran, H., and Doseff, A.I. Modulation of caspase-3 enzymatic activity by PKCδ phosphorylation during apoptosis. (Poster). The 9th Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H., Parihar, A., Huang, Q., Wood, K., and Doseff, A.I. Determination of cellular life spam from cells of the innate and adaptive immune system by the heat shock protein 27. (Poster). The Ninth Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, Ohio
  
  
  • Cardenas, H., Nicholas, C., Grotewold, E., and Doseff A.I. Apigenin reduces mortality in a mouse model of acute lung injury by inhibiting neutrophil infiltration, MIP-2, and apoptosis in the lungs. (Poster). 12th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Heine, George., Wang, L., Freitas, MA., Grotewold, E., and Doseff, A.I. Anti-proliferative mechanisms of the flavonoid apigenin. (Poster). 12th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio

  2009:

  • Doseff, A.I., Voss, O.H., Gonzalez-Mejia, M.E. The small heat shock protein 27 regulates monocyte/macrophage survival and differentiation. (Poster). American Thoracic Society International Conference, San Diego, CA 
  
  
  • Voss, O.H, Malavez, Y., Gonzalez-Mejia, M.E., Batra, S., and Doseff, A.I. Regulation of cell fate by PKCδ-depednent phosphorylation of caspase-3 and its association with Hsp27. (Best Oral Presentation). Falkenthal Memorial Graduate Student Colloquium. The Ohio State University, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Nihcolas, C., Grotewold, E., Freitas, M., and Doseff, A.I. Apigenin induces DNA damage in a PKCδ-dependent manner. (Poster). The 3rd Annual Davis Heart and Lung Research Institute Research Retreat. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H, Parihar, A, Huang, Q., Wood, K., and Doseff, A.I. Determination of cellular life span through the intearction of caspase-3 with PKCδ and Hsp27. (Poster). The Third Annual Davis Heart and Lung Research Institute Research Retreat. The Ohio State University, Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Murnan, and Doseff, A.I. Caspase-3 phosphorylation is mediated by the association of PKCδ and Hsp27 during apoptosis. (Poster). The Third Annual Davis Heart and Lung Research Institute Research Retreat. The Ohio State University, Columbus, Ohio
  
  
  • Voss, O.H, Parihar, A, Huang, Q., Porcu, P., Wood, K., and Doseff, A.I. Regulation of CD8+CD57+ lymphocytes cell fate by heat shock proteins. (Poster, Awarded 1st Place Graduate student category). 11th Annual OSU-Medical Center Research Day, Columbus, Ohio
  
  
  • Arango, D., Morohashi, K., Grotewold, E., and Doseff, A.I. (Poster). Molecular mechanisms of apigenin-induced DNA damage. (Poster). 11th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Voss, O.H, Parihar, A, Huang, Q., Pierluigi, P., Wood, K., and Doseff, A.I. The small heat shock protein 27 regulates CD8+CD57+ lymphocytes cell fate. (Poster). 11th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Murnan, E., Voss, O.H., and Doseff, A.I. Regulation of apoptosis by the association of caspase-3 with hsp27: role of Hsp27 phosphorylation. (Poster, Awarded 2nd Place Post-doc category). 11th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Murnan, E., Gonzalez-Mejia, M.E., Voss, O.V., and Doseff, A.I. Post-translational modifictaion and regulation of the chaperone Hsp27 during apoptosis. (Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Kamran, H., Malavez, Y., Voss, O.H., and Doseff, A.I. Molecular mechanisms of caspase-dependent apoptosis. (Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Murnan, E., Gonzalez-Mejia, M.E., and Doseff, A.I. Role of Hsp27 in apoptosis. (Poster). 11th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Pasupuleti, N., Matsuyama, S., Doseff, A.I. and Nagaraj, R. The chaperone and anti-apoptosis are intimately related functions in human A-crystallin. (Poster). Association for Research in Vision and Ophthalmology (ARVO). Ft. Lauderdale, FL
  
  
  • Kamran, H., Malavez, Y., Voss, O.H., and Doseff, A.I. Molecular mechanisms of caspase-dependent apoptosis. (Poster). College of Biological Sciences Undergraduate Research Colloquium. The Ohio State University, Columbus, OH. The Ohio State University, Columbus, Ohio
  
  
  • Murnan, E., Gonzalez-Mejia, M.E., Voss, O.V., and Doseff, A.I. Post-translational modifictaion and regulation of the chaperone Hsp27 during apoptosis. (Poster). College of Biological Sciences Undergraduate Research Colloquium. The Ohio State University, Columbus, OH. The Ohio State University, Columbus, Ohio
  
  

  2008:

  • Arango, D., Morohashi, K., Nicholas, C., Wang, L., Grotewold, E., Freitas, M., and Doseff, A.I. (Poster). Molecular mechanisms of apigenin-induced apoptosis. (Poster). Third Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y.*, Voss, O.H., Doolittle, J., and Doseff, A.I. PKCδ dependent phosphorylation of caspase-3 modulates cell death during innate immune response (Poster). Third Annual Pulmonary Research Day. The Ohio State University. Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Murnan, E., and Doseff, A.I. PKCδ-dependent phosphorylation of caspase-3 and its association with Hsp27 regulate life span during apoptosis. (Poster, 1st place postdoc category). Third Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Malavez, Y.*, Voss, O.H., and Doseff, A.I. The role of caspase-3 in cell death (Oral presentation). Third Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University. Columbus, Ohio
  • Voss, O., Parihar, A., Huang, Q., Wood, K.L., and Doseff, A.I. Apoptosis is regulated by the interaction of caspase-3 with PKCδ and Hsp27. (Poster, 1st place graduate student category). 3rd Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Parihar, A., Voss, O., Huang, Q., Wood, K.L., and Doseff, A.I. Hsp27 and the Bcl-2 family proteisn as regulators of apoptosis in CD57+/- lymphocytes. (Poster). Third Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Murnan, E., Gonzalez-Mejia, M.E., and Doseff, A.I. Apigenin-indiced Hsp27 phosphorylation (Poster). Third Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio
  
  
  • Crisafi, S.*, Malavez, Y., and Doseff, A.I. Regulation of caspase-3 by PKCδ (Poster). The Ohio Student Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Wood, K.L., Huang, Q., Phillips, G.S., Shamo, E.N., Marsh, C.B., Baran, C., Moffat-Bruce, S., Pope-Harman, A., Nunley, D.R., and Doseff, A.I. The role of Heat shock protein 27 in Bronchiolitis obliterans after lung transplantation. (Poster discussion). American Thoracic Society International Conference, Ontario, Canada
  
  
  • Voss, O.H., Malavez, Y., Gonzalez-Mejia, M.E., Batra, S., and Doseff, A.I. Regulation of cell fate by caspase-3, PKCδ, and Hsp27. (Poster-Awarded best graduate student poster). 7th Annual OSU-Medical Center Research Day, Columbus, Ohio
  
  
  • Doolittle, J.M., Aguda, B., Doseff, A.I. Mathematical model of the intrinsic pathway of apoptosis. (Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Murnan, E., Gonzalez-Mejia, M.E., and Doseff, A.I. Regulation of apoptosis by caspase-3 by hsp27. (Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio
  
  
  • Shamo, E.N., Huang, Q., Batra, S., Doseff, A.I., and Wood, K. The association of heat shock proteins and alloimmunity after bone marrow transplant. (Poster). 7th Annual OSU-Medical Center Research Day, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Doolittle, J., and Doseff, A.I. Regulation of apoptosis by PKCδ-dependent phoshorylation of caspase-3 (Poster). 7th Annual OSU-Medical Center Research Day, Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Voss, O.H., and Doseff, A.I. PKCδ and Hsp27 regulate monocyte/macrophage cell fate by its direct interaction with caspase-3. (Poster). 7th Annual OSU-Medical Center Research Day, Columbus, Ohio
  
  
  • Doolittle, J.M., Aguda, B., Doseff, A.I. Mathematical modeling of PKCδ-mediated activation of caspase-3 during cell death. (Awarded Best Poster). College of Biological Sciences Undergraduate Research Colloquium. The Ohio State University, Columbus, Ohio 
  
  
  • Murnan, E., Gonzalez-Mejia, M.E., and Doseff, A.I. Regulation of apoptosis by caspase-3 by hsp27. (Poster). College of Biological Sciences Undergraduate Research Colloquium. The Ohio State University, Columbus, Ohio
  
  
  • Doolittle, J.M., Aguda, B., Doseff, A.I. Mathematical modeling of PKCδ-mediated activation of caspase-3 during cell death. (Poster). 10th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Voss, O.H., Malavez, Y., Gonzalez-Mejia, M.E., Batra, S., and Doseff, A.I. Regulation of cell fate by caspase-3, PKCδ, and Hsp27. (Poster). 10th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Gonzalez-Mejia, M.E., Voss, O.H., and Doseff, A.I. Caspase-3-dependent apoptosis in monocyte/macrophage life span: role of Hsp27. (Poster). 10th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Malavez, Y., Voss, O.H., Doolittle, J., and Doseff, A.I. Regulation of apoptosis by PKCδ-dependent phoshorylation of caspase-3 (Poster). 10th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  
  • Nicholas, C., Batra, S., Vargo, M.A., Voss, O.H., Gavrilin, M.A., Guttridge,D., Wewers, M.D. Grotewold, E., and Doseff, A.I. Apigenin induces apoptosis in leukemia, and the inflammatory response in vitro and in vivo through the inhibition of NF-κB-p65. (Poster). 10th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio
  
  

• Presentations

  "Genetic screen to isolate genes involved in the function of SIT-4 phosphatiase." Presented at Meeting on Cell Cycle, Cold Spring Harbor, NY, US|USA. (January 1995)
  
  "Delineating the caspase cascade by caspase depletion." Presented at Meeting on Programmed Cell Death, Cold Spring Harbor, NY, US|USA. (January 1997)
  
  "Spontaneous monocyte apoptosis and endotoxin protection are dependent on caspase-3 and do not require caspase-1 activity." Presented at FASEB, Washington, DC, US|USA. (January 2000)
  
  "Caspases: regulating by proteolysis the apoptotic cascade." Presented at American Thoracic Society International Conference, Toronto, CA|CAN. (January 2000)
  
  "Caspase-3 phosphorylation and its role in monocyte apoptosis." Presented at American Thoracic Society International Conference, Toronto, CA|CAN. (January 2000)
  
  "Caspase-3 is a phosphoprotein and associates with a kinase that is modulated during monocyte activation and spontaneous monocyte apoptosis." Presented at Keystone Symposia, Keystone, CO, US|USA. (January 2001)
  
  "Mechanisms of cell death." Presented at Internal Medicine Fellows Day, Columbus, OH, US|USA. (January 2001)
  
  "IL-4 induces apoptosis of activated monocytes through a caspase-dependent pathway." Presented at American Thoracic Society International Conference, San Francisco, CA, US|USA. (January 2001)
  
  "Caspases: killer proteases inducing cell death." Presented at Molecular Biology and Cancer Genetics Program Conference, Columbus, OH, US|USA. (January 2001)
  
  "Killer caspases: The executioners of apoptosis in cancer and inflammation." Presented at Winthrop-University Hospital, Mineola, NY, US|USA. (January 2002)
  
  "Killer caspases: The good guys in cancer and inflammation." Presented at Seminar Series, Columbus, OH, US|USA. (January 2002)
  
  "Caspase-3 is a phsphoprotein that associates with and is phosphorylated selectively by a PKC isoform during monocyte lifespan." Presented at American Thoracic Society International Conference, GA, US|USA. (January 2002)
  
  "IL-4 induces apoptosis of activated monocytes by inducing ERK dephosphorylation and reactivation of caspases." Presented at American Thoracic Society International Conference, WA, US|USA. (January 2003)
  
  "Molecular mechanisms of apoptosis." Presented at Molecular and Cell Developmental Biology Program, The Ohio State University, OH, US|USA. (January 2003)
  
  "Apoptotic proteases as executioners of unwanted cells." Presented at Human Cancer Genetics, The Ohio State University, OH, US|USA. (January 2003)
  
  "When cells dye: pathways and approaches to study apoptosis." Presented at Sunrise Seminar, American Thoracic Society International Conference, WA, US|USA. (January 2003)
  
  "Caspase-3 is a phosphoprotein that associates with and is phosphorylated selectively by a PKC during monocyte lifespan." Presented at American Thoracic Society International Conference, Seattle, WA, US|USA. (January 2003)
  
  "Mechanisms of apoptosis in cancer and innate immunity." Presented at University of Buenos Aires, (January 2003)
  
  "Killer caspases: executing cell death by proteolysis." Presented at University of Buenos Aires, (January 2003)
  
  "Caspases: Regulating monocyte lifespan during innate immunity." Presented at The Heart and Lung Research Institute, The Ohio State University, OH, US|USA. (January 2003)
  
  "Small heat shock proteins are differentially regulated and their localization varies during human monocyte apoptosis and prolonged survival." Presented at American Thoracic Society International Conference, Orlando, FL, US|USA. (January 2004)
  
  "Caspases controlling life and death in cancer and immunity." Presented at Department of Molecular Genetics, The Ohio State University, OH, US|USA. (January 2005)
  
  "Flavonoids: anti-cancer and anti-inflammatory compounds." Presented at Therapeutic Team, Department of Internal Medicine, The Ohio State University, OH, US|USA. (January 2005)
  
  "Apoptosis." Presented at Basic Research Conference, Div. Pulmonary and Critical Care, The Ohio State University, OH, US|USA. (January 2005)
  
  "Regulation of programmed cell death: implications for cancer and inflammation." Presented at Graduate Program in Oral Biology Seminar Series, The Ohio State University, US|USA. (January 2006)
  
  "Executioners caspases controlling life and death in cancer and immunity." Presented at University of Buenos Aires, Buenos Aires, AR|ARG. (January 2006)
  
  "Apoptosis: sculptor of development." Presented at Meeting for Gynecologic Investigation, Toronto, CA|CAN. (January 2006)
  
  "Regulation of apoptosis: implications for cancer and innate immunity." Presented at The Cleveland Clinic, Cleveland, OH, US|USA. (January 2007)
  
  "Regulation of cell fate: the caspases attack." Presented at Miami University, Oxford, OH, US|USA. (January 2007)
  
  "The flavonoid apigenin suppresses acute lung injury. (Oral Presentation)." Presented at Interdisciplinary Graduate Programs Symposium, Columbus, OH, US|USA. (January 2007)
  
  "Regulation of apoptosis by heat shock proteins and PKC." Presented at Case Western Reserve University, Cleveland, OH, US|USA. (January 2008)
  
  "Anti-inflammatory and anti-carcinogenic mechanisms of plant natural products." Presented at Pan-American Advance Studies Institute (PASI), PE|PER. (January 2008)
  
  "The role of Heat shock protein 27 in Bronchiolitis obliterans after lung transplantation." Presented at American Thoracic Society International Conference, Ontario, CA|CAN. (January 2008)
  
  "The small heat shock protein 27 regulates monocyte/macrophage survival and differentiation." Presented at American Thoracic Society International Conference, San Diego, CA, US|USA. (January 2009)
  
  "Natural immune-regulators: alternative therapeutic approaches in acute lung injury." Presented at Department of Internal Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Columbus, OH, US|USA. (January 2009)
  
  "Regulation of cell fate in leukocytes." Presented at National Academy of Medicine, Buenos Aires, AR|ARG. (August 2010)
  
  "Mechanisms of cell fate during inflammation of cancer." Presented at Department of Pharmacology, Columbus, OH, US|USA. (January 2010)
  
  "Anti-proliferative mechanisms of the flavonoid apigenin." Presented at 12th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, OH, US|USA. (January 2010)
  
  "Heat shock proteins and caspases in the regulation of cell fate and immunity." Presented at Tel-Aviv University, Tel-Aviv, IL|ISR. (March 2011)
  
  "Two to Tango: heat shock proteins and caspases in the regulation of cell fate." Presented at Department of Molecular Genetics, Columbus, OH, US|USA. (February 2011)
  
  "Caspases and heat shock proteins: inflammation tuning by cell death." Presented at The Davis Heart and Lung Research Institute, Columbus, OH, US|USA. (July 2011)
  
  "PD-Seq:Coupling phage-display with next-generation sequencing towards the identification of human cellular targets of the flavonoid apigenin and development of flavonoids nanosensors." Presented at Gordon Conference-Plant Metabolic Engineering, Waterville Valley, NH, US|USA. (July 2011)
  
  "Regulation of apoptosis: implications for cancer and innate immunity." Presented at Stony Brook University, Stony Brook, NY, US|USA. (April 2011)
  
  "Anti-cancer and anti-inflammatory molecular mechanisms of dietary plant flavonoids." Presented at Interdepartmental Seminar in Nutrition, Columbus, OH, US|USA. (April 2011)
  
  "Plants for health: regulatory networks controlling inflammation and cancer." Presented at University of Mayaguez, PR|PRI. (November 2012)
  
  "Plants for health: from education and research to the clinic." Presented at Flora Braziliensis, Columbus, OH, US|USA. (February 2012)
  
  "Heat shock proteins and apoptotic caspases define complex survival and apoptotic regulatory networks controlling cell fate and inflammation." Presented at Northeast Ohio Medical University, OH, US|USA. (September 2012)
  
  "Role of caspase-3 in cell fate: novel partners define a complex regulatory network." Presented at International Cell Death Symposium, BR|BRA. (October 2012)
  
  "Flavonoids-target identification and development of biosensors." Presented at B3 Tripartite OSU-Rutgers-Univeristy of Sao Paulo, Columbus, OH, US|USA. (May 2012)
  
  "Complex regulatory interactions of survival and apoptotic proteins determine cell fate by tuning caspase activity." Presented at University of Sao Paulo, Brazil, Sao Paulo, BR|BRA. (April 2013)
  
  "Identification of human targets of the dietary flavone apigenin reveals novel aspects of the anti-carcinogenic and anti-inflammatory mechanisms of phytochemicals." Presented at Gordon Conference-Plant Metabolic Engineering, Waterville Valley, NH, US|USA. (July 2013)
  
  "Dietary flavonoids: targeting cancer and inflammation." Presented at Department of Horticulture and Crop Sciences, Columbus, OH, US|USA. (November 2013)
  
  "Survival and apoptotic networks regulate cellular lifespan." Presented at Department of Molecular Genetics, Columbus, OH, US|USA. (September 2013)
  
  "MALCS (Mujeres Activas en Letras y Cambio Social: Women active in social studies and languages) – STEM session." Presented at Bridging the Gap: underrepresented groups in STEM, Columbus, OH, US|USA. (July 2013)
  
  "Novel mechanisms of dietary medicinal phytochemicals identified through a comprehensive genome-wide approach: implications for cancer and inflammation." Presented at American Council for Medically Active Plants, Fargo, ND, US|USA. (June 2014)
  
  "Human targets of dietary flavonoids identified using a novel approach PD-Seq. reveals novel aspects of the anti-carcinogenic and anti-inflammatory mechanisms of phytochemicals." Presented at The 8th Tripartite Workshop, Rutgers University, University of São Paulo, Brazil, and The Ohio State University, NJ, US|USA. (November 2014)
  
  "Protein networks in cellular life span: implication for cancer and inflammation." Presented at Chemistry and Biology Interface Training Program (CBIP), Columbus, OH, US|USA. (October 2014)
  
  "Survival and apoptotic regulatory networks: implications for cancer and inflammation." Presented at Department of Physiology and Cell Biology, Columbus, OH, US|USA. (May 2014)
  
  "Cel-KIBCAN: celery to kill breast cancer." Presented at Translational Breast Meeting, Columbus, OH, US|USA. (February 2015)
  

• Unpublished Works

  Gonzalez-Mejia, E., Voss, O.H., and Doseff, A.I. Phosphorylation of Hsp27 during apoptosis mediates PKCo-dependent phosphorylation of caspase-3. February 2015
  
  Arango, D., Mejia-Guerra, K., Grotewold, E., and Doseff, A.I. Genome-wide regulation of alternative splicing by dietary apigenin controls anti-apoptotic-associated resistance in breast cancer.. March 2015
  
  Cardenas, H.*, Arango, D.*, Nicholas, C., Duarte, S., Gonzalez-Mejia, E., Nuovo, G., Grotewold, E., and Doseff, A.I.. Dietary apigenin regulates lipopolysaccharide-induced pulmonary inflammation by restoring metabolic function and reducing leukocyte infiltration. *Indicates shared first authorship.. June 2015
  
  Mejia-Guerra, K., Li, Wei, Doseff, A.I.# and Grotewold, E.#. Core promoter plasticity between maize tissues and genotypes contrasts with predominance of sharp transcription initiation sites. # Indicates shared senior corresponding author. July 2015
  
  Voss, O.H., Malavez, Y., and Doseff, A.I. Specific docking sites of PKCδ on caspase-3 induce phosphorylation and positively regulates apoptosis.. July 2015
  
  Arango, D., Pereira, M., Duarte, S., and Doseff, A.I. NFkB-dependent regulation of proliferative and immune-regulatory activity of dietary apigenin in breast cancer. August 2015
  
  Voss, O., Tossey, J., Arango, D., Grotewold, E., and Doseff, A.I. Chemo-sensitization of lung cancer by dietary apigenin through changes in alternative splicing promoting the activation of DISC formation. May 2015

  
  

Advising

• Undergraduate Advising Narrative

  Fellowships awarded to my undergraduate students 

  (14 since my last promotion)

  • Arts and Sciences Research Fellowship, 2014 - 2015
    
    • Shao, Q. (student) Doseff, A.I. (mentor)
    • Total award: $2,000

  • Arts and Sciences - Thomas Byers Memorial Fellowship, 2013 - 2014
    
    • Rice, E. (student) Doseff, A.I. (mentor)
    • Total award: $2,000

  • Comprehensive Cancer Center - Pelotonia Undergraduate Fellowship, 2012 - 2013
    
    • Tossey, J. (student) Doseff, A.I. (mentor)
      • Title: The role of flavones in Hsp27-regulated apoptosis in non-small cell lung carcinomas
    • Total award: $14,000

  • Arts and Sciences Honor Undergraduate Research Scholarship, 2011 - 2012
  • Tossey, J. (student) Doseff, A.I. (mentor)
    • Title: Regulation of cell death by the small heat shock protein 27 
  • Total award: $7,000

  • American Heart Association Undergraduate Fellowship, Summer 2011
  • Tossey, J. (student) Doseff, A.I. (mentor)
    • Title: Mechanisms of the anti-apoptotic heat shock protein 27 in doxorubicin-induced cardiomyocyte apoptosis 
  • Total award: $4,000

  • Undergraduate Student Government Academic Enrichment Grant, Travel Award, April 2012
  • Tossey, J. (student) A.I. (mentor)
  • Total award: $1,000 to attend the Experimental Biology Meeting

  • Pressey Honors Grant— Competitive award provides funds to attend a conference. Experimental Biology, 2012
  • Tossey, J. (student) Doseff, A.I. (mentor)
  • Total award: $300

  • Sharp Undergraduate Scholarship, 2009
  • Kamran, H. (student) Doseff, A.I. (mentor) 
  • Total award: $1,000

  • The Mayers Summer Research Internship Award, Summer 2009
  • Kamran, H. (student) Doseff, A.I. (mentor) 
    • Title: Molecular regulation of caspase-3
  • Total award: $4,000

  • The Mayers Summer Research Internship Award, Summer 2008
  • Murnan, E. (student) Doseff, A.I. (mentor) 
    • Title: Role of heat shock proteins in cell death
  • Total award: $4,000

  • The Mayers Summer Research Internship Award, Summer 2007
  • Doolittle, J. (student) Doseff, A.I. (mentor) 
    • Title: Mechanisms of the regulation of apoptosis: mathematical and system biology 
  • Total award: $4,000

  • Glenn-Stokes Summer Research Internship at OSU — The student is from University of Dayton, Summer 2007
    • Arasu, M. (student) Doseff, A.I. (mentor) 
      • Title: Pathways of cell fate
    • Total award: $4,500

  • The Mayers Summer Research Internship Award, Summer 2004
  • Reno, E. (student) Doseff, A.I. (mentor) 
    • Title: Mechanisms of caspase-3 regulation by hsp27
  • Total award: $3,000

  • Arts and Sciences Undergraduate Research Scholarship, Winter 2003
  • Vargo, M. (student) Doseff, A.I. (mentor) 
    • Title: The role of caspase-3 regulation in cell death of breast cancer cells
  • Total award: $1,000

  • OSU-CCC Summer Internship Program, Summer 2002
  • Sancaktar, O. (student) Doseff, A.I. (mentor) 
    • Title: Mechanisms of FAS-dependent apoptosis 
  • Total award: $2,500 and travel award for meeting

  • Undergraduate Enrichment Fund from College of Biological Sciences, Spring 2004
    • Kolattukudy, S.J. (student) Doseff, A.I. (mentor) 
      • Title: Mechanisms of caspase-3 and hsp27 in apoptosis
    • Total award: $300

  • Dean’s College of Biological Sciences Undergraduate Research Award
  • Kamran, H., Winter 2010
  • Kamran, H., Winter 2009
  • Kamran, H., Fall 2008
  • Murnan, E., Winter 2008
  • Doolittle, J., Winter 2007
  • Taylor, C., Winter 2006
  • Kollatukudy, S.J., Winter 2004
  • Reno E., Fall 2004
  • Vargo, M., Spring 2002

  • Total award in each case: $300

  
  

  Awards received by my undergraduate and post-baccalaureate students for best poster presentations
  (* indicates name of undergraduate and # indicates name of post-baccalaureate; six since my last promotion)

  
  

  2015 Alers Velazquez,# R.M., Li, W., Valentin Morales, J., Prada Salcedo, L.D., Gray, J., Grotewold, E., and Doseff, A.I. (Poster, March 21-22, Awarded best poster). Characterization of PALs transcriptional regulatory network in maize. ASPB Midwestern Conference. St. Louis. MI

  2012 Tossey, J.*, Voss, O.H., and Doseff, A.I. Molecular Identification of Hsp27 Anti-Apoptotic Activity. (Poster Awarded 2nd place). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio

  2011 Tossey, J.*, Voss, O.H., and Doseff, A.I. Molecular fingerprinting of Hsp27-anti-apoptotic activity. (Poster-October 11, Awarded 2nd place undergraduate student category). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio

  2011 Brahimaj, B.*, Arango, D., and Doseff, A.I. Molecular mechanisms of anti-carcinogenic flavonoids. (Poster-May11, Awarded Best Poster). Denman Undergraduate Research Forum. The Ohio State University, Columbus, Ohio

  2011 Tossey, J.*, Voss, O.H., and Doseff, A.I. Molecular identification of Hsp27-anti-apoptotic activity. (Poster-April 29. Awarded Best Poster). Natural and Mathematical Sciences Undergraduate Research Forum. The Ohio State University, Columbus, Ohio

  2008 Doolittle, J.M.*, Aguda, B., Doseff, A.I. Mathematical modeling of PKCδ-mediated activation of caspase-3 during cell death. (Awarded Best Poster). College of Biological Sciences Undergraduate Research Colloquium. The Ohio State University, Columbus, Ohio

  
  

  Publications by my undergraduate and post-baccalaureate students
  (* indicates undergraduate and # indicates post-baccalaureate; seven since my last promotion)

  
  Arango, D., Diosa-Toro, M.#, Rojas-Hernandez, L.S.#, Cooperstone, J.L., Schwartz, S., Mo. X., Jiang, J., Schmittgen, T.D., and Doseff, A.I . (2015). Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation. Mol. Nutrit. Food Res. 59: 763-772
  
  

  Gray, J., Burdo, B., Goetting-Minesky, M. P., Wittler, B., Hunt, M., Li, T., Velliquette, D., Thomas, J., Key, K., Gentzel, I., dos Santos Brito, M., Mejía-Guerra, M.K., Connolly, L. N., Qaisi, D.*, Li, W., Casas, M. I., Doseff, A.I., and Grotewold, E. (2015). Protocol for the Generation of a Transcription Factor Open Reading Frame Collection (TFome). BioProtocols. (In Press)
  
  Burdo, B., Gray, J., Goetting-Minesky, M. P., Wittler, B., Hunt, M., Li, T., Velliquette, D., Thomas, J., Gentzel, I., dos Santos Brito, M., Mejía-Guerra, M.K., Connolly, L. N., Qaisi, D.*, Li, W., Casas, M. I., Doseff, A.I., and Grotewold, E. (2014). The Maize TFome: Development of a transcription factor open reading frame collection for functional genomics. Plant J. 2: 353-366. PMID: 25053252
  
  Arango, D., Morahashi, K., Yilmaz, A., Kuramichi, K., Parihar, A., Brahimaj, B.*, Grotewold, E., and Doseff, A.I. (2013). Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets. Proc. Natl. Acad. Sci. USA. 110: E2153-2162. PMID: 23697369
  
  Hostetler, G., Schwartz. S., Diosa-Toro, M.#, Riedl, K., Arango, D., and Doseff, A.I. (2012). Flavone deglycosylation increases their anti-inflammatory activity and absorption. Mol. Nutrit. Food Res. 56: 558-569. PMID: 22351119
  
  Gonzalez-Mejia, M.E., Voss, O.H., Murnan, E.J.*, and Doseff, A.I. (2010). Apigenin-induced-apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of Heat Shock Protein 27. Cell Death Disease. 1:e64. PMID: 21364669
  
  Wood, K. L., Nunley, D.R., Moffat-Bruce, S., Pope-Harman, A., Huang, Q., Shamo, E.N.*, Philips, G.S., Barna, C., Batra, S., Marsh, C.B., and Doseff, A.I. (2010). The role of Heat Shock Protein 27 in Bronchiolitis obliterans syndrome after lung transplantation. J. Heart and Lung Transplantation. 29: 786-791. PMID: 20456980
  
  Voss, O.H., Batra, S., Kolattukudy, S.J.*, Gonzalez-Mejia, M.E., Smith, J., and Doseff, A.I. (2007). Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation. J. Biol. Chem. 282: 25088-25099

  
  

  Additional undergraduate students trained in my laboratory

  Name of Summer Program (13 since my last promotion)
  

  • Li, Joanna, honor student pre-medicine, 2012 - 2015
  • Shao, Quinhui, honor student molecular genetics, 2012 - 2015
  • Rice, Erin, honor student molecular genetics, 2012 - 2013
  • Sarmiento, Cristina, honor student biology, 2010 - 2012
  • Sterner, Zacchary, REU (research experience undergraduate) - molecular genetics, 2015
  • Bliss, Alessandra, REU (research experience undergraduate) - molecular genetics, 2015
  • Nardone-White, Dasean, REU (research experience undergraduate) - molecular genetics, 2014
  • Taitano, Daniel, research experience undergraduate (SUCCESS), 2014
  • Samantha, Valdez, research experience undergraduate (SUCCESS), 2013
  • Matos, Nieve, Adrianna, SROP, 2013
  • Harder, Matthew, REU (research experience undergraduate) - molecular genetics, 2013
  • Hong, Harry, research experience undergraduate (SUCCESS), 2012
  • Garza, Johan, REU (research experience undergraduate) - molecular genetics, 2012
  • Tietz, Kiel, REU (research experience undergraduate) - molecular genetics, 2011
  • Hernandez, Jennifer, REU (research experience undergraduate) - molecular genetics, 2010
  • Crisafi, Sean, REU (research experience undergraduate) - molecular genetics, 2008
  • Benson, Jennifer, 2008

• Noteworthy Graduate Narrative

  Fellowships and awards received by my graduate students

  (Nine since my last promotion)
  

  • Colciencias (NSF equivalent from Colombia) pre-doctoral fellowship, 2015 - 2018
    
    • Duarte, S. (predoctoral student) Doseff A.I. (mentor) 
      • Title: Immune-regulatory mechanisms of dietary flavonoids 
    • Total award: $150,000

  • Keystone Symposia Future of Science Fund Scholarship, 2014
    
    • Keystone Symposia. Silverthorne, CO. Competitive fellowship covered the trip to attend the Keystone Meeting
    • Arango, D. (predoctoral student) Doseff A.I. (mentor)

  • Pelotonia Pre-doctoral Research Fellowship, 2013 - 2015
    
    • Arango, D. (predoctoral student) Doseff A.I. (mentor)
      • Title: Molecular mechanisms of dietary flavonoids in breast cancer: novel role of nutraceuticals inregulating alternative splicing
    • Total award: $53,000

  • Food and Innovation Center Research Student Grant, 2013 
  • Arango, D. (predoctoral student) Doseff A.I. (mentor)
    • Title: Chemopreventive mechanisms of newly formulated apigenin-rich diets in breast cancer
  • Total award: $5,000

  • Travel Award Best Poster Presentation 12th Trainee Research Day College of Medicine, 2013
  • Arango, D. (predoctoral student) Doseff A.I. (mentor)
  • Total award: $1,000

  • Food and Innovation Center Travel Award to attend the Experimental Biology Meeting, 2013
  • Arango, D. (Predoctoral student) Doseff A.I. (Mentor)
  • Total Award: $500

  • Enlaza Mundos, Master Student Fellowship from Univ. Colombia, Medellin, 2011 - 2012
  • Pineda, C. (student) Doseff A.I. (mentor)
    • Title: Regulation of flavones in adipogenesis 
  • Total award: $15,000

  • PHPID-Predoctoral Fellowship (Public Health Preparedness for Infectious Diseases), 2011 
  • Arango, D., (predoctoral student) Doseff A.I. (mentor)
    • Title: Regulation of the TLR-mediated innate immune response by the flavonoid apigenin
  • Total award: $35,000

  • American Heart Association Predoctoral Fellowship, 2006 - 2009
  • Voss, O. (predoctoral student) Doseff A.I. (mentor)
    • Title: Regulation of human monocyte apoptosis by caspase-3 and small heat shock proteins
  • Total award: $42,000
  • Graduate school approved and waived the full cost of tuition

  Awards received by my graduate students for best poster presentations

  (* indicates the name of the graduate student awardee; 13 since my last promotion)
  
  2013:

  • Arango, D.*, Morohashi, K., Yilmaz, A., Brahimaj, B., Kuramochi, K., Parihar, A.,Grotewold, E. and Doseff A.I.(Poster-April 11- Awarded 1nd place graduate student category). The 12th Annual Ohio State University Medical Center and Graduate and Postgraduate Trainee Research Day. The Ohio State University, Columbus, Ohio

  2012: 

  • Duarte San Miguel, S.*, Pineda, C., Arango, D., and Doseff A.I. Effect of apigenin on metabolic dysfunction in adipose tissue. (Poster-May 31. Awarded best poster) The 9th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio

  2011: 

  • Arango, D.*, Morohashi, K.,Yilmaz, A., Guttridge, D.C., Hei, W., Kuramochi, K., Grotewold, E., and Doseff A.I. Innovative approach towards understanding the anti-inflammatory mechanisms of the flavonoid apigenin. (Poster-October 11, Awarded 2nd place graduate student category). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio

  • Hostetler, G.*, Riedl, K., Cardenas, H., Diosa-Toro, M., Schwartz, S., and Doseff A.I. Deglycosilation of flavones enhances anti-inflammatory activity of food extracts in vitro and absorption of dietary flavones from celery in mice. (Poster-April 9-14; Selected oral presentation). Experimental Biology, Washington, DC

  2010:

  • Malavez, Y.*, and Doseff A.I.Role of PKCδ dependent phosphorylation of caspase-3 on programmed cell death. (Selected Plenary talk, 1st place award). The Interdisciplinary Graduate Programs Symposium in the Molecular Life Sciences (MCDB, OSBP, and Biophysics). The Ohio State University, Columbus, Ohio

  • Arango, D.*, Morohashi, K., Wang, L., Heine, G., Freitas, M. A., Grotewold, E. and Doseff A.I.Anti-carcinogenic mechanisms of the plant flavonoid apigenin. (Poster, 1st place). The 7th Annual Russell Klein Nutrition Research Symposium. The Ohio State University, Columbus, Ohio 

  • Voss, O.H.*, Parihar, A., Huang, Q., Wood, K., and Doseff A.I. Determination of cellular life span from cells of the innate and adaptive immune system by the heat shock protein 27. (Poster, 1st place Graduate student category). The Ninth Annual Ohio State University Medical Center and Graduate and Postgraduate Research Day. The Ohio State University, Columbus, Ohio 

  2009:

  • Voss, O.H.* and Doseff A.I. Regulation of caspase-3 by heat shock proteins. (Oral presentation, third place). 35th Edward F. Hayes Graduate Research Forum. The Ohio State University, Columbus, Ohio

  • Voss, O.H.*, Parihar, A, Huang, Q., Porcu, P., Wood, K., and Doseff A.I. Regulation of CD8+CD57+ lymphocytes cell fate by heat shock proteins. (Poster, 1st place Graduate student category). Eighth Annual OSU-Medical Center Research Day, Columbus, Ohio

  • Voss, O.H.* and Doseff A.I. Regulation of caspase-3 by heat shock proteins. (Oral presentation, third place graduate student category). Scott Falkenthal Memorial Graduate Student Colloquium. The Ohio State University, Columbus, Ohio

  2008:

  • Voss, O.*, Parihar, A., Huang, Q., Wood, K.L., and Doseff A.I.Apoptosis is regulated by the interaction of caspase-3 with PKCδ and Hsp27. (Poster, 1st place). Third Annual Research day-Div. Pulmonary, Allergy Critical Care and Sleep Medicine. The Ohio State University, Columbus, Ohio

  • Voss, O.H.*, Malavez, Y.*, Gonzalez-Mejia, M.E., Batra, S., and Doseff A.I. Falkenthal Memorial Graduate Student Colloquium. Regulation of cell fate by PKCδ-dependent phosphorylation of caspase-3 and its association with hsp27. (Best oral presentation). The Ohio State University, Columbus, Ohio

  • Voss, O.H.*, Malavez, Y.*, Gonzalez-Mejia, M.E., Batra, S., and Doseff A.I. Regulation of cell fate by caspase-3, PKCδ, and Hsp27. (Best graduate student poster). The Seventh Annual OSU-Medical Center Research Day. The Ohio State University, Columbus, Ohio

  2007:

  • Nicholas, C.*, Batra, S., Vargo, M.A.*, Voss, O.H.*, Gavrilin, M.A., Guttridge,D., Grotewold, E., Wewers, M.D. and Doseff A.I.The flavonoid apigenin suppresses acute lung injury. (Poster presentation selected for Oral, second place best oral presentations). 1th Molecular Life Sciences Interdisciplinary Graduate Programs Symposium. The Ohio State University, Columbus, Ohio

  • Sharma, A.*, Vargo, M.A.*, Voss, O.H.*, Batra, S., and Doseff A.I. (Apigenin-induced apoptotic release of histones H2B and H4 to the cytoplasm. (Poster). Second place in poster presentations). The Second Annual Davis Heart and Lung Research Institute Research Retreat. The Ohio State University, Columbus, Ohio

  2006:

  • Voss, O. H.* and Doseff A.I. Caspase-3 phosphorylation by PKCδ has a proapoptotic effect. (Poster, best graduate student poster). The Fifth Annual Medical Center Graduate and Postgraduate Research Day. The Ohio State University, Columbus, Ohio

  • 2006 Voss, O.H.*, Sharma, A.* and Doseff A.I. Biennial Retreat Molecular Biology and Cancer Genetics Program. Atwood Lake Resort, Ohio. (Best poster selected for podium presentation)

  Publications by my graduate students

  (* indicates the graduate student name; 15 since my last promotion)
  
  Parihar, A., Duarte, S.* and Doseff A.I. (2015). The saga of food supplements: safety and missing knowledge. Commentary in: J. Med. Active Plants. (In Press)
  
  Arango, D.*, Diosa-Toro, M., Rojas-Hernandez, L.S., Cooperstone, J.L., Schwartz, S., Mo. X., Jiang, J., Schmittgen, T.D., and Doseff A.I. (2015). Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation. Mol. Nutrit. Food Res. 59: 763-772
  
  Malavez, Y.*, Voss, O.*, Parihar, A., Gonzalez-Mejia, M.E. and Doseff A.I. (2015). Distinct contribution of PKCδ and PKCε in the lifespan and immune response of human blood monocyte subpopulations. Immunology. 144: Issue 4: 611–620
  
  Casas, M.I., Duarte, S.M.*, Doseff A.I.#, and Grotewold, E#. (2014). Flavone-rich maize: An opportunity to improve the nutritional value of an important commodity crop. Frontiers in Plant Sciences (In Press). 5: 1-11. #Shared corresponding author. PMID: 25250036
  
  Duarte, S.*, Arango, D.*, Yasmeen, R. Parihar, A., Hamel, P., and Doseff A.I. (2013). Apigenin protects endothelial cells of LPS-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function. International Journal of Molecular Sciences. 14: 17664-17679. PMID: 23989609
  
  Arango, D.*, Morahashi, K., Yilmaz, A., Kuramichi, K., Parihar, A., Brahimaj, B., Grotewold, E., and Doseff A.I. (2013). Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets. Proc. Natl. Acad. Sci. USA. 110: E2153-2162. PMID: 23697369
  
  Naomi, R.B., Wang, B., Voss, O.*, Doseff A.I., Santhoshkumar, P. and Nagaraj, R.H. (2013). Chaperone peptides of α-crystallin inhibit epithelial cell apoptosis, protein insolubilization and opacification in experimental cataracts. J. Biol. Chem. 288. 13022-13035. PMID: 23508955
  
  Arango, D.*, Parihar, A., Villamena, F.A., Wang, L., Freitas, M.A., Grotewold, E., and Doseff A.I. (2012). Apigenin induces DNA damage through the PKCδdependent activation of ATM and H2AX causing down-regulation of genes involved in cell cycle control and DNA repair. Biochem. Pharmacol. 4: 1571-1580. PMID: 22985621
  
  Das, A., Gopalakrishnan, B., Voss, O.H.*, Doseff A.I.and Villamena, F.A. (2012). Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling. Biochem. Pharmacol. 84: 486-497. PMID: 22580046
  
  Hostetler, G.*, Schwartz. S., Diosa-Toro, M., Riedl, K., Arango, D.,* and Doseff A.I. (2012). Flavone deglycosylation increases their anti-inflammatory activity and absorption. Mol. Nutrit. Food Res. 56: 558-569. PMID: 22351119
  
  Akhter, A., Caution, K., Khweek, A.A., Tazi, M.F., Abdulrahman, B.A., Abdelaziz, D.H., Voss, O.H.*, Doseff A.I., Hassan, H., Azad, A.K., Schlesinger, L.S., Wewers, M.D., Gavrilin, M.A., Amer, A.O. (2012). Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin independently of caspase-1. Immunity 37: 35-47. PMID: 22658523
  
  Gonzalez-Mejia, M.E., Voss, O.H.*, Murnan, E.J., and Doseff A.I. (2010). Apigenin-induced-apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of Heat Shock Protein 27. Cell Death Disease. 1:e64. PMID: 21364669
  
  Wood, K.L., Voss, O.H.*, Huang, Q., Parihar, A., Metha, N., Batra, S., and Doseff A.I. (2010). The small heat shock protein 27 is a key regulator of CD8+CD57+ lymphocyte survival. J. Immunol. 184:5582-5588. Selected for “In this issue” special editor’s commentary. PMID: 20385876
  
  Pasupuleti, N., Matsuyama, S., Voss, O.H.*, and Doseff A.I., Song, K., Danielpour, D., Nagaraj, R. (2010). Anti-apoptotic functions of human A-crystallin: relation to the chaperone function. Cell Death and Disease. 1(3):e31. PMID: 221364639
  
  Malavez, Y.*, Gonzalez-Mejia, M.E., and Doseff A.I. (2008). PKCδ. Atlas Genet Cytogenet Oncol Haematol. http://AtlasGeneticsOncology.org/Genes/

  Patents
  (* Indicates the name of the graduate student)

  • Processes for improving absorption and anti-inflammatory activity of dietary flavones
  • Inventors: Doseff A.I., Schwartz, S., Hostetler, G.*, Riedl, K., Cardenas, H., 2011

• Postdoctoral and Researcher Advising

  Currently in my laboratory

  • Wei Li — postdoctoral researcher, 2012 - present
  • Marcelo Pereira — postdoctoral researcher, 2014 - present

  Post-docs trained in my laboratory and current positions

  • Voss, Oliver H., PhD Postdoctoral Researcher, currently postdoc at NIH, 2010 - 2013
  • Yasmeen, Rumana, PhD Postdoctoral Researcher, currently postdoc at OSU, 2013 - 2013
  • Parihar, Arti, PhD, visiting professor, currently associate professor, Government Post Graduate College Center of Excellence, Ujjain, MP, India, 2011 - 2012
  • Gonzalez-Mejia, Martha Elba, MD, PhD, postdoctoral researcher, currently assistant professor at the University of Puebla, Mexico, 2006 - 2012
  • Cardenas, Horacio, PhD, research scientist, currently research assistant professor, Indiana University, 2009 - 2010
  • Batra, Sanjay, PhD, postdoctoral researcher, currently research associate professor, Southern University and A&M College, 2006 - 2007
  • Batra, Sanjay, PhD, visiting scientist, 2003 - 2004
  • Heine, George, PhD, postdoctoral fellow, currently lecturer, 2009 - 2010
  • Porchia, Leonardo, PhD, postdoctoral fellow, currently research associate, 2007 - 2008
  • Parihar, Arti, PhD, postdoctoral researcher, 2008 - 2009
  • Omata, Waka, PhD, postdoctoral researcher, current research associate, 2008 - 2009
  • Kovinick, Nikolas, PhD, (co-advisor: Doseff, A.I.) postdoctoral researcher, current assistant professor at the University of West Virginia, 2012 - 2015

  Post-doctoral fellowships awarded to my postdocs

  • Science without borders, Post-doctoral Research Fellowship from Brazil, 2014 - 2016
    
    • Pereira, M. (postdoc) Doseff, A.I. (mentor)
      • Title: Regulatory networks responsible for the health beneficial effects of apigenin
    • Total award: $50,000

  • Travel Award Best Poster Presentation 12th Trainee Research Day College of Medicine, 2013
    
    • Voss, O. (postdoc) Doseff, A.I. (mentor)
    • Total award: $1,000

  • Pelotonia Post-Doctoral Research Fellowship, 2012 - 2014
    
    • Kovinich, N. (postdoc) E. Grotewold (mentor) Doseff, A.I. (co-mentor)
      • Title: New Frontiers in the Chemical Arsenal Against Cancer: Combining Modules of Semi-Synthesis and Synthetic Biology
    • Total award: $98,600

  • NCI-Ruth L. Kirschstein, 2009 - 2010
    
    • Heine, G., (postdoc) Doseff, A.I. (mentor)
      • Title: The role of BRCA1 in response to DNA damage
    • Total award: $45,000

  • NIH-T32, 2008 - 2009
    
    • Porchia, L., (postdoc) Doseff, A.I. (mentor)
      • Title: Regulation of monocyte fate by caspase 3, Heat Shock Protein 27 and Protein Kinase Cδ
    • Total award: $44,000

  Awards received by my post-docs for best poster presentations
  (* indicates name of the postdoctoral awardee; eight since the last promotion)

  2014:

  • Yang, F.*, Li, W., Doseff, A.I.. and Grotewold, E. (Awarded 2nd Best Poster). The 8th Tripartite Workshop, Rutgers University, University of São Paulo, Brazil, and The Ohio State University. For sustainable technology innovations: integrating biology and chemistry for energy, food security and medicine. Rutgers, New Jersey. (Poster-Nov. 14-17)

  2013:

  • Voss, O.H.*, Tossey, J., and Doseff, A.I. Anti-apoptotic proteins: essential regulators of monocyte to macrophage life span and differentiation. (Poster-April 11- Awarded 1nd place post-doc category). The 12th Annual Ohio State University Medical Center and Graduate and Postgraduate Trainee Research Day. The Ohio State University, Columbus, Ohio

  2011:

  • Voss, O.H.*, Tossey, J., and Doseff, A.I. Role of Hsp27 in monocyte to macrophage life span and differentiation. (Poster-October 11, Awarded 1st place postdoc category). Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio

  2010:

  • Voss, O.*, Parihar, A., Huang, Q., Wood, K., and Doseff, A.I. Hsp27 determines cell fate of cell cells from the innate and adaptive immune system by regulating the activation of caspase-3. (Poster- 1st place postdoc category). The 5th Annual Pulmonary, Allergy, Critical Care and Sleep Research Day. The Ohio State University, Columbus, Ohio

  • Cardenas, H.*, Nicholas, C., Nishijima, Y., Nuovo, J., and Doseff, A.I. The anti-inflammatory flavonoid apigenin reduces mortality in a mouse model of acute inflammation by inhibiting lung neutrophil infiltration and reducing MIP-2 chemokine expression. (Poster, awarded 1st place staff category). The 10th anniversary Davis Heart and Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio

  • Voss, O.*, and Doseff, A.I. Monocytes and macrophages life span is regulated by the association of caspase-3 with Hsp27. 2010. (Poster, 1st place postdoc category). The 10th Annual Dorothy M. Davis Heart & Lung Research Institute Research Day. The Ohio State University, Columbus, Ohio2009 González-Mejia M.E.*, Murnan E.J., Voss O.H.+, and Doseff, A.I. Apigenin-induced a bimodel phosphorylation of heat shock protein 27 via p38-MAPK and PKCδ regulates mitochondrial depolarization during apoptosis. (Poster). Cell Death Meeting. Cold Spring Harbor Laboratory. Cold Spring Harbor, NY. Travel Award

  2009: 

  • Gonzalez-Mejia, M.E.*, Murnan, E., Voss, O.H., and Doseff, A.I. Regulation of apoptosis by the association of caspase-3 with hsp27: role of Hsp27 phosphorylation. (Poster, 2nd Place Post-doc category). 11th OSU-Comprehensive Cancer Center Annual Scientific Meeting, Columbus, Ohio

  2007:

  • Batra, S.*, Nicholas, C., Vargo, M.A., Voss, O.H., Gavrilin, M.A., Guttridge,D., Grotewold, E., Wewers, M.D. and Doseff, A.I. The flavonoid apigenin regulates the production of inflammatory cytokines by promoting the dephosphorylation and inactivation of NF-κB in LPS stimulated monocytes. (Poster selected for Podium presentation, third place best oral presentation). The Second Annual Davis Heart and Lung Research Institute Research Retreat. The Ohio State University, Columbus, Ohio

• Master Graduate Advising

  Doctoral students
  (Dissertations committee member)
  

  • National 
  • Wang, T-Y. A., (2013)
  • Hostetler, G. co-advisor, (2013)
  • (Candidacy examination committee chair)
  • Woods, P. Biomedical Sciences PhD Graduate Program, (2013)
  • Hostetler, G. Food and Technology Graduate Program, College Food and Technology, (2011)

  (Candidacy examination committee member)
  

  • National 
  • Kara Braunreiter, Molecular Genetics Graduate Program, (2015)
  • Meriam Waqas, Molecular Genetics Graduate Program, (2014)
  • Jeremy Baeten, Biomedical Sciences PhD Graduate Program, (2013)
  • Tse-Yao Arthur Wang, Molecular Cellular Developmental Biology Program, (2011)
  • Claudia Berdugo, College of Engineering, (2009)

  • International
  • Echeverri, L., 2015
  • Institution: University of Medicine CES-Medellin, Colombia, February 15
  • Rodrigues da Silva, D.I., 2014
  • Institution: Dual PhD Program OSU-University São Paulo, Brazil

  Visiting scholars (international post-baccalaureates) trained in my laboratory 

  (Nine since the last promotion)
  

  • Prada-Salcedo, L., 2014 - present
  • Institution: B.S. Pontificia University Javeriana, Bogota, Colombia and M.Sc. National University of Colombia, Bogota

  • Rojas, L., 2014
  • Institution: University of Antioquia, Medellin, Colombia

  • Merchand-Reyes, G., 2014
  • Institution: B.S. Biology and Pharmaceutical chemistry, National University of Mexico (UNAM). MSc. In Immunology, National School of Biol. Sci. Mexico

  • Florez, L., 2012 - 2014
  • Institution: University of Antioquia, Medellin, Colombia

  • Duarte-San Miguel, S., 2012 - 2013
  • Institution: University of Bogota, Colombia

  • Wafula, M., 2012 - 2013
  • Institution: University of Nairobi, Kenya

  • Pineda-Molina, C., 2011 - 2012
  • Institution: National University of Colombia, Medellin, Colombia

  • Diosa-Toro, M., 2010 - 2011
  • Institution: University of Antioquia, Medellin, Colombia

  • Federico, M. B., 2009 - 2010
  • Institution: University of Buenos Aires, Argentina

  Post-baccalaureate students trained in my laboratory

  (Nine since the last promotion)
  

  • Morales-Montilla, D. SiGuE (Success In Graduate Education) fellow-NSF, (2015-present)
  • Alers Velazquez, R. SiGuE (Success In Graduate Education) fellow-NSF, (2014-2015)
  • Lopez, E. SiGuE (Success In Graduate Education) fellow-NSF, (2014-2015)
  • Valentin, J. SiGuE (Success In Graduate Education) fellow-NSF, (2013-2014)
  • Kayanga, G. SiGuE (Success In Graduate Education) fellow-NSF, (2013-2013)
  • Mills, M. SiGuE (Success In Graduate Education) fellow-NSF, (2013-2013)
  • Warren, T. R25-Discovery Prep (NIH), (2011)
  • Apiagyei, M. R25-Discovery Prep (NIH), (2010)
  • Cordero, H. R25-Discovery Prep (NIH), (2010)

  Graduate students rotations

  • 15 since 2008

• Academic Advising

  • Academic advising of a Research Associate 2012-1014. My role included planning of the daily experimental schedule, data interpretation and preparation of results for publication. I conducted weekly meetings and revised notebooks daily
  
  
  • Advising visiting scholars (9 since my last promotion). My roles include developing projects, helping students in setting experiments, analyzing data and interpreting results. I meet with trainees one to one weekly and during our weekly lab
  
  
  • Advising of STEM underrepresented undergraduate students (10 since my last promotion). I host students in my lab as part of three summer initiatives: the SROP OSU program, the Molecular Genetics-Biochemistry REU program and the SUCCESS program. My roles include developing projects, helping students to set experiments, analyze data, prepare data for presentations and developing critical thinking. In addition, I meet with them weekly one to one, I attend their oral, poster and journal club presentations, I meet with parents (SUCCESS program) and attend events such as dinners, banquets etc. I also revise their written projects and continue being in touch with most of them over the years
  
  
  • Advising SiGuE post-baccalaureate fellows (6 since my last promotion). My roles include developing projects, helping students in setting experiments, analyzing data and interpreting results. Developing opportunities to increase their self-esteem and provide orientation for application to graduate school or professional careers. I meet with trainees one to one weekly and during our weekly lab.
  
  
  • I advised a junior faculty Dr. Marketton, 2009 - 2013
  
  
  • In my laboratory I advice postdocs, graduate and undergraduate students. My roles include conducting weekly meetings to discuss experiments, develop their projects, assisting in data analyses and preparation of data for presentations and publications. I provide advice in fellowship’s preparation and presentations (21 fellowships/scholarships and 27 awards for best presentations were obtained by my trainees since my last promotion)
  
  
  • Advising graduate students in the Translational Plant Sciences program and serving as graduate studies committee (GSC) member. This is a different program characterized by a personalized curriculum. Students together with the GSC decide their minimum number of courses to take, meeting with the GSC are scheduled twice a year and presentations of students to the GSC take place at least once a year

• Academic Advisees

  • M.E. Gonzalez-Mejia, The Ohio State University, graduated 2006 (present)
  • Duarte. S, The Ohio State University, (2014 - present)
  • S.J. Kolattukudy, The Ohio State University, graduated 2006, The Role of Hsp27 in Human Monocyte Apoptosis, (2008 - present)
  • Elaine Michelle, The Ohio State University - Regulation of caspase-3 by Hsp27, (2006 - present)
  • Arango, D, The Ohio State University, graduated 2015, The immune-modulatory and anti-carcinogenic mechanisms of the flavonoid apigenin, (2008 - 2015)
  • Tossey, J, The Ohio State University, Title: Molecular Mechanisms of apoptosis resistance, (2010 - 2013)
  • Pineda, C, National University of Columbia, graduated 2013, Effects of the flavonoid apigenin in adipocyte differentiation and immune-response, (2011 - 2012)
  • Greg Hostetler, The Ohio State University, graduated 2012, Mechanisms of caspase-3 regulation in the execution of cell death, (2007 - 2012)
  • Malavez, Y, The Ohio State University, graduated 2012, Mechanisms of caspase-3 regulation in the execution of cell death, (2006 - 2012)
  • Brahimaj, B, The Ohio State University, Title: Molecular mechanisms of anti-carcinogenic flavonoids, (2009 - 2011)
  • Hayes, S, The Ohio State University, (2009-2011)
  • Hector Cordero, The Ohio State University, (2010)
  • Margaret Apiagyei, The Ohio State University, (2010)
  • Jennifer Hernandez, The Ohio State University, (2010)
  • Yager-Schweller, J, The Ohio State University, (2009-2010)
  • Kamran, H, The Ohio State University, Title: Molecular mechanisms of caspase-3 dependent apoptosis, (2007-2010)
  • Voss, O.H, The Ohio State University, graduated 2010, Regulation of apoptosis by caspase-3, (2004-2010)
  • Murnan, E, The Ohio State University, Title: Mechanisms of heat sock protein 27 in apoptosis, (2007-2009)
  • Nicholas, C, The Ohio State University, graduated 2009, The anti-inflammatory mechanisms of the flavonoid apigenin in vitro and in vivo, (2005-2009)
  • Speakman, J.J, The Ohio State University, graduated 2009, (2004-2009)
  • Doolittle, J, The Ohio State University, Title: Mechanisms of the regulation of apoptosis (2006-2008)
  • Vargo, M, The Ohio State University, graduated 2008, The anti-carcinogenic and anti-inflammatory mechanisms of the flavonoid apigenin in mammalian cells, A (2006-2008)
  • Sharma, The Ohio State University, (2005-2007)
  • olattukudy, S.J, The Ohio State University, Title: The role of hsp27 in human monocyte apoptosis, (2002 - 2006)
  • Reno, E, The Ohio State University, Title: Regulation of caspase-3 by hsp27 (2003 - 2006)
  • Vargo, M., The Ohio State University, graduated 2006, The anti-carcinogenic and anti-inflammatory mechanisms of the flavonoid apigenin (2003 - 2006)

• Courses Taught

  Undergraduate courses

  • Molecular Genetics 500 (Department of Molecular Genetics – core class for undergraduate students), 2002 - 2009
  • Credit hrs: 5, students enrolled: 275 to 325. Period: Fall quarter.
  • Content: Molecular biology and genetics. Course for non-major genetic students
  • Contribution: I was responsible for half of all the lectures, designing half of the midterms and half of the final. I managed six to seven teaching assistants and provided office hours

  • Atlas Genome Journal Club. Offered: January to May 2013, twice a month, 2013
  • Students attending: 11
  • Content: knowledge of latest technologies used for genome-wide analysis including Gateway cloning, yeast one and two hybrid, introduction to software used in GWAS analyses and bioinformatics approaches to identify gene regulatory networks 
  • Contribution: I developed the curriculum. I presented 50% of all the 30 min. lectures and I was responsible of promoting and mediating the discussions. I selected the articles presented in class. The other 50% of the lectures were done by one of my postdocs as part of her career’s development plan
  
  

  • Molecular Genetics 699/4998-4999. Research for undergraduate students, 2002 - present
  • Credits hrs: 1 to 5. Students enrolled: one to four depending the semester, taught all semesters
  • Content: This course is for undergraduate students performing research in my laboratory
  • Contribution: I meet with students one-to-one once per week to discuss experimental design, analyze data, prepare data for publication
  
  

  • Molecular Genetics H783/4999-4998. Research for honor students, 2002 - present
  • Credits hrs: 1 to 5. Students enrolled: one to three depending on the semester. Taught all semesters
  • Content: This course is for students performing research in my laboratory that are conducting an honor research thesis
  • Contribution: I meet with students once per week one-to-one to teach them how to design experiments. We also meet once a week in lab meetings as a group, where trainees will present current progress of their research. I teach students interpreting data, write fellowship, scientific articles, posters and the honor thesis. I also help students with oral presentations

  
  

  Graduate courses

  • Molecular Genetics 5796. Topics in Signal Transduction, 2013 - present
  • Credits hrs: 1 to 2. Students enrolled: eight (in 2013) and 13 (in 2014). Fall semester
  • The course is directed to PhD students from several different programs including: molecular genetics, molecular cellular and development biology, OSBP, nutrition, optometry and by senior undergraduate students from different majors
  • Content: Network theory applied to signal transduction pathways involved contributing to the pathophysiology of inflammatory diseases and cancer. As part of the course students were also required to present an article in groups followed by discussion and write an abstract that was graded
  • Contribution: I developed the curriculum, provided 100% of the lectures, developed and graded final, midterms, exercises and presented a hands-on workshop on large data analyses
  
  

  • Molecular Genetics 660. Integrated Molecular and Cellular Biology for non-biologist I, 2009 - 2012
  • Credit hrs: 5. Students enrolled: eight to 12 depending on the year. Fall semester
  • Content: This course was intended for master and PhD students in mathematics. The course consisted in lectures, interactive activities and included also one week of laboratory experience and one day of poster presentations by the students and three days of manuscript presentations
  • Contribution: I developed the curriculum in collaboration with Drs. H. Chamberlain and E. Grotewold. I taught 40% of all the lectures during the fall semester, developed and graded midterms and finals. Lead discussion during paper presentations
  
  

  • Molecular Genetics 8999, 2002 - present
  • Credits hrs: 1 to 4 depending of the semester. Students enrolled: one to four depending of the year. Taught all semesters of all years as faculty
  • Content: Laboratory research for PhD students
  • Contribution: I meet with students once per week, I teach them how to design experiments and help them with data interpretation. I teach students to write fellowship and manuscripts. I also help students with poster and oral presentations. I teach them rational and critical thinking. We also meet once a week for two hours for lab meetings
  
  

  • IBGP703-3-Module II, 2002 - 2012
  • Credits hrs: 2. Students enrolled: 20 to 28 depending of the year. Spring quarter
  • Content: Mechanisms of sepsis
  • Contribution: I was responsible of one lecture, developed part of the midterm and the final corresponding to my lecture
  
  

  • IBGP706, 2002 - 2012
  • Credits hrs: 2. Students enrolled: 25 to 30 depending of the year. Fall quarter
  • Content: Seminar for students
  • Contribution: I was responsible of a two-hour lecture
  
  

  • Molecular Genetics 801, 2007 - present
  • Credits hrs: 1. Students enrolled: three to nine depending of the year. Taught all year
  • Content: Seminar series, presentation for incoming students
  • Contribution: I contribute with one presentation
  
  

  • Molecular Genetics 795, 2002 - 2012
  • Credits hrs: 1. Students enrolled: one to four depending of the year. Taught all year
  • Content: Seminar series, presentation for incoming students
  • Contribution: I contribute with one presentation per quarter or semester, lead discussion, teaching students how to present their findings
  
  

  • Interdepartmental Seminar in Nutrition-ANIMSCI 898; FDSCTE 898; HUMNNTR 898, 2011
  • Credits hrs: 2. Students enrolled: 60. Human nutrition, animal sciences and food science and technology. Contributed with one lecture, April 8, 2011
  • Content: Seminar presentation for master and graduate students about mechanisms of nutraceuticals
  • Contribution: I was responsible for a 2 hour lecture
  
  

  • MCDB 800. Molecular Cellular and Developmental Biology, 2007 - present
    
  • Credits hrs: 1. Students enrolled: 25 to 32 depending of the year. Fall semester
  • Content: Seminar series, presentation of scientific projects for incoming students
  • Contribution: I contribute with one presentation

  Professional courses

  • Immunology Review Seminars, 2002 - 2008
    
  • Students attending: 5. Taught all year
  • Content: Topics in apoptosis, basic molecular biology, molecular genetics and signal transduction
  • Contribution: I contributed with eight, two hour lectures. These weekly seminars for postdoctoral and fellows was part of Training Grant Pulmonary and Critical Care (NIH-T32) educational development program

  Courses and presentation for professional development

  (only listed since the last promotion)

  • Career development panel discussion for undergraduate students SUCCESS program (June 15), The Ohio State University, 2015
  • Professional development series for women faculty: Finding your faculty career niche (January 15), The Ohio State University, 2014
  • American Heart Association grant development panel discussion for graduate students and postdocs (May), The Ohio State University, 2014
  • Building research leaders. Gender initiatives in STEM, Project CEOS and the Women’s place. Finding your faculty career niche (February 28), The Ohio State University, 2014
  • Development of international training programs (April 12), University of São Paulo, Brazil, 2013
  • Opportunities for graduate education in STEM disciplines (November 22), University of Mayaguez, Puerto Rico, 2012

  Continuing education, extension and other courses taught

  • Atlas Genome Journal Club. Offered: January to May 2013, twice a month, 2013
    
  • Students attending: 11
  • Content: knowledge of latest technologies used for genome-wide analysis including Gateway cloning, yeast one and two hybrid, introduction to software used in GWAS analyses and bioinformatics approaches to identify gene regulatory networks
  • Contribution: I developed the curriculum. I presented 50% of all the 30 min. lectures and I was responsible of promoting and mediating the discussions. I selected the articles presented in class. The other 50% of the lectures were done by one of my postdocs as part of her career’s development plan