Location: BRT 378
Yanbo.fan@osumc.edu
Dr. Fan’s research aims to elucidate how dynamic changes in vascular cell states drive vascular dysfunction and disease progression. His laboratory investigates the molecular mechanisms underlying atherosclerosis, aortic aneurysms and peripheral artery disease, as well as the interplay between vascular biology and systemic conditions such as diabetes and cancer therapy-induced cardiotoxicity.
His work addresses critical aspects of vascular pathophysiology, including how inflammation, phenotypic switching, cellular metabolism, autophagy-lysosome function and intercellular communication contribute to disease development. Dr. Fan’s team employs an integrated approach that combines cellular, molecular, biochemical, imaging, sequencing and in vivo models to uncover novel mechanisms and identify therapeutic targets in cardiovascular disease.
Education
MD: Hebei Medical University
PhD: Peking University
Postdoctoral Research Fellow: University of Michigan, Ann Arbor
Research Interests
- Atherosclerosis
- Peripheral artery disease
- Aortic aneurysms
- Cardio-oncology
- Endothelial dysfunction
- Vascular inflammation
- Autophagy-lysosome pathway
Professional Activities
- American Heart Association
- North American Vascular Biology Organization
Honors and Awards
- 2019 Aiken Award, Frankel Cardiovascular Center, University of Michigan,
- 2017 McKay Award, Frankel Cardiovascular Center, University of Michigan,
- 2008 The Outstanding Academic Research Award, Peking University
- 2008 Award for Outstanding Research Paper, Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, China
- 2007 Guanghua Prize for Excellence in Graduate Study, Peking University
Current Funding
- NIH R01HL171495
- NIH R01HL167024
- NIH R01HL145176