Associate Professor, Microbial Infection and Immunity
520 Biomedical Research Tower (BRT)
460 W 12th Ave, Columbus OH 43210
huang.5460@osu.edu
Research Interests
There is a growing understanding that improper regulation of metabolism is a key factor in various human diseases, including cancer. Exploring the manipulation of metabolism to enhance or suppress immune responses presents a groundbreaking concept that can shed new light on both innate and adaptive immunity.
At the forefront of the field of immunometabolism, the Huang Laboratory is dedicated to advancing our knowledge in immunology. The lab's research focuses on translational immunometabolism, aiming to unravel the mechanisms by which cytokines, nutrient fluctuations, unconventional mediators, and cellular signaling govern the development and fate of immune cells in both healthy and diseased individuals. Currently, our projects delve into the investigation of immunological function and metabolism in cancers, as well as the understanding of innate immune pathways, particularly the roles of macrophages and innate lymphoid cells (ILCs) in chronic inflammatory diseases, including inflammatory bowel disease (IBD), Alzheimer's disease (AD), and parasitic helminth infection.
Embracing interdisciplinary collaboration, our lab strives to understand the intricate interplay between cell function, metabolism, and immunity. Through this approach, we aim to identify novel therapeutic targets and develop innovative strategies to modulate immune responses and combat a wide range of human diseases.
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Laboratory
520 Biomedical Research Tower (BRT)
460 W 12th Ave, Columbus OH 43210
Lab website
Personnel
Lydia Raines, MSc, Graduate Student (CWRU), lydia.raines@osumc.edu
Lemin Li, PhD, Postdoctoral Scholar, lemin.li@osumc.edu
Haoxin Zhao, PhD, Postdoctoral Scholar, haoxin.zhao@osumc.edu