Associate Professor, Microbial Infection and Immunity

786 Biomedical Research Tower
460 W 12th Ave, Columbus OH 43210
Stephanie.Seveau@osumc.edu
614-247-7671

Membership:  Infectious Diseases Institute

Research Interests

Dr. Seveau's laboratory focuses on molecular mechanisms underlying host-pathogen interactions using Listeria monocytogenes as a model facultative intracellular pathogen. Specific projects currently are to: (1) establish how L. monocytogenes infects mammalian cells and tissues, (2) determine the molecular basis and outcomes of host-cell signaling in response to listeriolysin O, the major virulence factor of L. monocytogenes and a member of the cholesterol-dependent cytolysin (CDC) toxins, and (3) elucidate the mechanisms underlying the anti-toxin and immune-modulatory activities of antimicrobial peptides that belong to the defensin family.

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Laboratory

770 Biomedical Research Tower
460 W 12th Ave, Columbus OH 43210
614-247-7674

Personnel

Abbie Courtright, Research Assistant, courtright.69@osu.edu
Marilynn Ng, Research Assistant, marilynn.ng@osumc.edu
Nara Shakaki, Undergraduate Student, shakaki.1@osu.edu