Andrea Tedeschi, PhD
Associate Professor
Neuroscience
Academic information
- Department: Neuroscience
Research interests
- Neurotrauma
- Stroke
- Axon Growth and Regeneration
About
Biography
Traumatic brain and spinal cord injuries cause profound neurological deficits and long-term disability due to detrimental alterations of neuronal circuits. Although axonal injury is associated with several neurobehavioral and neuropathological characteristics, how changes in intrinsic neuronal properties alter interaction between neurons and non-neuronal cells remains a central mystery in neuroscience. Much of the progress to address this question has come from either studies that use in vitro surrogate models or in vivo endpoint studies. These experimental models, however, do not provide the spectrum of variables that influence the behavioral or systemic changes that occur in response to CNS trauma. It is our goal to shed some light on this important research topic and decipher the coding principle altering neuron circuit structure and function.
Credentials
Education
- Postdoctoral Training
- Harvard Medical School, Boston Children's Hospital, Boston, MA, United States
- Postdoctoral Training
- DZNE, Bonn, Germany
- PhD - Cell & Molecular Neuroscience
- International Max Plank Research School, Tuebingen, Germany
- MS - Biology and Biotechnology
- Insubria University, Varese, Italy
Research
Research interests
- Neurotrauma
- Stroke
- Axon Growth and Regeneration
Research Approaches
We take advantage of a multidisciplinary approach that combines transcriptomics, bioinformatics, genetic, molecular and pharmacological approaches together with in vivo time-lapse multiphoton microscopy and whole-body optical clearing.