Ashley Ingiosi, PhD
Assistant Professor
Neuroscience
Academic information
- Department: Neuroscience
Research interests
- Sleep
- Astrocytes
- Homeostasis
- Biological Rhythms
- Glial-Neuronal Interactions
About
Biography
Sleep is an essential pillar of physical and mental health, and insufficient sleep contributes to a variety of diseases and disorders. Our current understanding of how sleep is regulated is primarily derived from the study of neurons, but accumulating evidence shows non-neuronal cells called astrocytes also play a role. The Ingiosi Lab studies how astrocytes and neurons interact to regulate sleep. We use a multifaceted approach that allows us to investigate astrocytes and astroglial-neuronal interactions at the molecular, cellular, and circuit levels while also monitoring behavior and physiology. Determining how non-neuronal cell types contribute to brain processes like sleep is vital to understanding normal and abnormal neural physiology and behavior in health and disease.
Credentials
Education
- Postdoctoral Training
- Washington State University, Spokane, WA, United States
- PhD
- University of Michigan, Ann Arbor, MI, United States
Research
Research interests
- Sleep
- Astrocytes
- Homeostasis
- Biological Rhythms
- Glial-Neuronal Interactions
Research Techniques
We use a combination of techniques that includes electroencephalography, electromyography, in vivo imaging (e.g., miniscope, two-photon microscopy, calcium imaging), optogenetics, biological rhythms monitoring, viral vectors, proteomics, and immunohistochemistry in genetic mouse models to determine the molecular and cellular basis of sleep expression and regulation.