- About this researcher
Harry Fu, PhD
Associate Professor
Neuroscience
Academic information
- Department: Neuroscience
Research interests
- Alzheimer’s Disease
- Tau Pathology
- Neurotrauma
- Glial Pathology
- ER Stress
About
Biography
One of the fundamental questions common to all of the neurodegenerative diseases is why a particular disease targets specific neuronal populations? My research focuses on understanding which subtypes of neurons are vulnerable to tau pathology in early Alzheimer’s disease (AD) and other tauopathies as well as the molecular and cellular mechanisms underlying the selective neuronal vulnerability. In particular, they are interested in investigating the role of cell-autonomous (neurons) versus cell non-autonomous (microglia, astrocytes and oligodendrocytes) effects as well as aging in selective vulnerability to proteinopathies in neurodegenerative diseases.
Credentials
Education
- Postdoctoral
- Columbia University, New York City, NY, United States
- Postdoctoral
- Brigham and Women's Hospital, Boston, MA, United States
- Postdoctoral
- The Jackson Laboratory, Bar Harbor, ME, United States
- PhD
- The Hong Kong University of Science and Technology, Hong Kong, China
Research
Research interests
- Alzheimer’s Disease
- Tau Pathology
- Neurotrauma
- Glial Pathology
- ER Stress
Research Approaches
We utilize a multidisciplinary approach that combines neuropathology, mouse genetics, neurobehavioral tests, confocal and light-sheet microscopy, molecular and cell biological approaches together with single cell RNA-seq and spatial transcriptomic analysis.
More about my research
News and media
My news coverage
- Ohio State study reveals new insights into neurodegeneration
- Study explores how traumatic brain injury (TBI) may be linked to Alzheimer's disease
- Ohio State develops searchable database for Alzheimer's research
- Research explores why certain brain neurons are vulnerable to degeneration
- Study Shows One Type of Brain Cell May Invite Alzheimer's
