Harry Fu, PhD

Associate Professor

Neuroscience

Harry Fu

Academic contact

Phone: 614-293-6810

Hongjun.Fu@osumc.edu

Academic information

  • Department: Neuroscience

Research interests

  • Alzheimer’s Disease
  • Tau Pathology
  • Neurotrauma
  • Glial Pathology
  • ER Stress

About

Biography

One of the fundamental questions common to all of the neurodegenerative diseases is why a particular disease targets specific neuronal populations? My research focuses on understanding which subtypes of neurons are vulnerable to tau pathology in early Alzheimer’s disease (AD) and other tauopathies as well as the molecular and cellular mechanisms underlying the selective neuronal vulnerability. In particular, they are interested in investigating the role of cell-autonomous (neurons) versus cell non-autonomous (microglia, astrocytes and oligodendrocytes) effects as well as aging in selective vulnerability to proteinopathies in neurodegenerative diseases.

Credentials

Education

Postdoctoral
Columbia University, New York City, NY, United States
Postdoctoral
Brigham and Women's Hospital, Boston, MA, United States
Postdoctoral
The Jackson Laboratory, Bar Harbor, ME, United States
PhD
The Hong Kong University of Science and Technology, Hong Kong, China

Research

Research interests

  • Alzheimer’s Disease
  • Tau Pathology
  • Neurotrauma
  • Glial Pathology
  • ER Stress

Research Approaches

We utilize a multidisciplinary approach that combines neuropathology, mouse genetics, neurobehavioral tests, confocal and light-sheet microscopy, molecular and cell biological approaches together with single cell RNA-seq and spatial transcriptomic analysis.

More about my research