Zhou_Min_460x460 Professor, Department of Neuroscience

4066C Graves Hall
333 West 10th Ave
Phone: 614-366-9406 

Research Focus

Dr. Zhou’s laboratory focuses on the physiology and pathophysiology of astrocytes, a glial subtype that are linked through conduit proteins, gap junctions, into a syncytium. The syncytial coupling has been indicated in their recent study to confer an isopotentiality to astrocytes network, by which astrocytes operate as a functional system in brain homeostasis. In ongoing studies, they are investigating 1) the anatomical basis, gap junction, ion channel mechanisms and biophysical rationale underlying this newly appreciated glial mechanism;  2) how neuronal signaling regulates the functional states of astrocyte syncytium, and that in turn, subserves brain homeostasis and synaptic transmission; and 3) how disruption of an astrocyte syncytium,  at both of the structural and functional levels, is etiologically associated with neurological disorders, such as stroke, epilepsy, and depression.


A variety of techniques and transgenic animal models are currently employed in Dr. Zhou’s laboratory to understand the structure and function of astrocytes: electrophysiology, confocal microscopy, blockface serial scanning EM, CUBIC tissue clearing, immunocytochemistry, RT-PCR, Western blots, and behavioral analysis. 

Education and Training

Degrees: Tongji Medical College, China and Friedrich-Schiller-University Jena, Germany
Postdoctoral: Albany Medical College, Dr. Harold Kimelberg

PubMed articles