Forming new connections

The Center for Medical and Engineering Innovation (CMEI) fosters interdisciplinary research through multiple initiatives that engage Ohio State faculty, staff, trainees, students and extramural entities whose focus is to expand innovation and impact at the intersection of medicine and engineering.

Research activities include:

• Organized lectures with tours of research facilities and equipment demonstrations to increase personnel familiarization with resources on campus.
• Workshops for attendees to gain additional laboratory equipment or software expertise.
• Collaborative interactions with existing Ohio State departments, centers, and institutes to expand utilization of resources in new and ongoing research endeavors.

CMEI recognizes that major advancements in medicine will involve a multitude of engineering-related disciplines such as nanotechnology and artificial intelligence. Engineers working in concert with health professionals will alter the landscape for patient care. New developments are broadly expected in areas including advanced therapeutics (e.g. targeted drug delivery) and diagnostics (e.g. biosensors) as well as implantable and wearable devices. CMEI strives to facilitate innovative solutions and transformative applications such as these in medicine by promoting local collaborative efforts between physicians and engineers.

If you’re interested in collaborating with CMEI on a research project or educational activity, please submit this electronic form.

Launching innovative projects: CMEI Pilot Grants

CMEI is pleased to announce its 2023-2024 Pilot Grant Awards. The awardees and their OSU affiliations and projects are listed below.

The CMEI pilot grant program supports collaborations between Ohio State colleges that initiate promising ventures at the medicine-engineering interface. Proposed research involve at least one faculty member from the College of Engineering and one faculty member from one of the Health Sciences Colleges. These collaborations test innovative approaches (ideas, technologies, devices) directed at basic or clinically relevant biomedical research. In funding awards, special consideration has been given to applications addressing specific topics such as telemedicine, wearable devices, robotics, novel materials and artificial intelligence/machine learning. Other topic areas are expected to be emphasized in future funding opportunities. Our program funds $35,000 grants to assist faculty in obtaining preliminary data that will result in a collaborative grant application for the NIH, or another agency or foundation, or lead to an entrepreneurial endpoint such as a patent.

Additionally, in partnership with the Center for Clinical and Translational Science (CCTS), pilot grant awardees are eligible to apply for a CCTS voucher for up to $5,000 funding support towards Ohio State University or Nationwide Children’s Hospital core service(s) that are part of the CCTS voucher program. These may include secure fee-based core services for services from CDME, DDDS or expert consultation services (such as biostatistics) with the ultimate goal of furthering clinical and translational research.

The next request for applications for CMEI pilot grant funding is likely to be announced in the late Spring of 2024. Please watch this space and various OSU news sources (e.g., onCampus, HealthBeat, etc.) for announcements.

The most recent round of proposals occurred in August, 2023. Awardees of CMEI Pilot Grants for the period 9/15/2023 – 9/14/2024 and their projects are:

• Nathan Doble, PhD (Opthalmology & Visual Science, COO) and Stacey Choi, PhD (Opthalmology & Visual Science, COO), Srinivasan Parthasarathy, PhD (Computer Science and Engineering, COE), and Rajiv Ramnath, PhD (Computer Science and Engineering, COE)
  Project: Generation of Optical Coherence Tomography (OCT) B-scan Images Directly from Spectrograph Data using AI
• Megan Malara, PhD (CDME, COE) and Kyle VanKoevering, MD (Otolaryngology, COM)
  Project: Development of a 3D Printing Platform Towards a Personalized, Tissue Engineered Vascularized Bone Scaffold
• Nicholas Ferrell, PhD (Nephrology, Internal Medicine, COM) and Natalia Higuita-Castro, PhD (Biomedical Engineering, COE)
  Project: Targeted Cellular Delivery of Nanoengineered Extracellular Vesicles for Acute Kidney Injury
  

The third round of proposals occurred in August, 2022. Awardees of CMEI Pilot Grants for the period 9/15/2022 – 9/14/2023 and their projects are:

• Asimina Kiourty, PhD (Electrical and Computer Engineering, COE) and Toshimasa Okabe, MD (Cardiovascular Medicine, COM)
  Project: Non-Invasive Determination of HV Interval Using a Wearable MagnetoCardioGraphy Sensor
• Timothy F. Plageman Jr., PhD (COO) and Katelyn Swindle-Reilly, PhD (Biomedical Engineering, COE) Project: Optimization of a Novel Technique to Bioengineer Lens Organoids
• Emanuele Cocucci, MD, PhD (Division of Pharmaceutics and Pharmacology, COP), Derek Hansford, PhD (Biomedical Engineering, COE) and Francesca Cottini, MD (Hematology, COM)
  Project: Development of a Localized, Time Controlled Perfusion System for Lattice Light Sheet Microscopy

The second round of proposals occurred in July, 2021. Awardees of CMEI Pilot Grants for the period 9/1/2021 – 8/31/2022 and their projects were:

• Jinghua Li, PhD (Materials Science and Engineering, COE) and Catherine Quatman-Yates, PhD (Division of Physical Therapy, COM)
  Project: A Wireless Sweat Patch for Endocrine Assessment during Music-Based Neuromodulation in TBI Patients
• Gunjan Agarwal, PhD (Mechanical and Aerospace Engineering, COE), Brian Foster, PhD (Biosciences, COD) and Maciej Pietrzak, PhD (Biomedical Informatics, COM)
  Project: Role of DDR1 in the Postmenopausal Bone
• Daniel Gallego-Perez, PhD (Biomedical Engineering, COE) and Yousef Hannawi, MD (Neurology, COM)
  Project: Nanotransfection-Driven Vasculogenic Cell Therapies for Alzheimer’s Disease and Age-Related Dementias
• Alper Yilmaz, PhD (Civil Env. and Geodetic Engineering, COE) and Deepak Gulati, MD (Neurology, COM)
  Project: Automated Detection of Subtypes of Intracranial Hemorrhage Using Deep Learning

The first round of proposals occurred in December, 2020. Awardees of CMEI Pilot Grants for the period 1/1/2021-12/31/2021 and their projects were:

• Allen Yi, PhD (Integrated Systems Engineering, COE) and Matthew Ohr, MD (Ophthalmology, COM)
  Project: Development of a Miniature Optical System for Microendoscopic Ophthalmoscopy
• Sheng Dong, PhD (Mechanical and Aerospace Engineering, COE) and Gregory J. Wiet, MD (Pediatric Otolaryngology, COM)
  Project: Pre-Operative Simulation and Optimization for Surgical Cochlear Implant Installation
• Samantha Krening, PhD (Integrated Systems Engineering, COE) and Jaysingh Singh, MD (Neurology, COM)
  Project: Real-Time Seizure Detection Using Machine Learning in Comatose Patients