KRISHNAKUMAR KIZHATIL, PhD
Assistant Professor
Ophthalmology and Vision Sciences
Academic information
- Department: Ophthalmology and Vision Sciences
Research interests
- Glaucoma
- Molecular basis of Intraocular pressure
About
Biography
I am a cell and developmental biologist working to find cures for glaucoma. He is an NIH-funded researcher focused on determining the molecular basis of intraocular pressure regulation. I use the mouse to understand the mechanistic basis of human glaucoma-associated gene functions and associated pathways to identify new druggable targets to control eye pressure and glaucoma. My group will use cutting edge cell biology methods genomics and state of the art microscopy to study the development and biology of Schlemm's canal, an essential structure for controlling eye pressure. My group aims to develop tools with clinical potential to control Schlemm’s canal function to reduce eye pressure. The Kizhatil group will also study retinal ganglion cell biology to develop therapies to enhance their resiliency to protect vision.
Credentials
Education
- Postdoctoral training - Department of Cell Biology and HHMI
- Duke University Medical Center, Durham, NC, United States
- PhD
- University of Tennessee at Memphis, Memphis, TN, United States
- Bachelor of Pharmacy (Honors, June 1992)
- Birla Institute of Technology and Science (BITS), Pilani, Rajasthan, India
Research
Research interests
- Glaucoma
- Molecular basis of Intraocular pressure
Active Funding
Determining Molecular mechanisms of Human glaucoma genes
NIH/NEI-R01 033015 co-PI
Project dates: 05/1/2022-03/31/2026
Direct costs: $1,000416
The objective of the grant is to determine the mechanism by which the human glaucoma gene GLIS1 regulates intraocular pressure using model eyes.
Professional membership
Association for Research in Vision and Ophthalmology (ARVO)
International Society for Eye Research (ISER)
American Society for Cell Biology (ASCB)
Editorial Activities
Ad hoc reviewer
Glaucoma Foundation,
Journal of Biological Chemistry,
Proceeding of National Academy of Science,
Investigative Ophthalmology and Visual Sciences (IOVS)
Experimental Eye Research
PlosOne
ELife
Molecular Vision
Survey of Ophthalmology
npj Regenerative Medicine
Cell Reports