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Takeshi Kurita, PhD

Associate Professor


Contact Information

Comprehensive Cancer Center
The Ohio State University
Biomedical Research Tower, Room 812
460 W. 12th Avenue
Columbus, OH 43210


Education and Training

PhD, Waseda University, Tokyo, Japan

Postdoctoral research, Department of Anatomy, University of California, San Francisco


Positions and Appointments

2007-2014: Research Associate Professor, Department of Obstetrics & Gynecology, Northwestern University

2004-2007: Research Scientist, Department of Cancer Endocrinology, BC Cancer Agency

2001-2004: Assistant Research Anatomist, Department of Anatomy, UCSF


Research Interest

My research interest lies in the molecular mechanisms of development and carcinogenesis of the reproductive organs. The current research subjects are:
  • Function of p53 family members in germ cell development and apoptosis. We are exploring the function of p53 family proteins in the germ cells utilizing mutant mouse models for Trp53, Trp63 and Trp73. The current research focus is the molecular mechanism that controls apoptosis in primordial oocytes.
  • Molecular etiology of vaginal adenosis and adenocarcinoma. Women exposed to diethylstilbestrol (DES) in utero are at risk to develop adenosis and adenocarcinoma of the cervix and vagina. The primary objective of this project is to elucidate the molecular pathogenesis of DES-associated vaginal adenocarcinoma. Our current focus is: 1. The signaling pathways that control cell fate in the Müllerian duct epithelial cells, and 2. The molecular mechanism through which DES disrupts the normal cell fate decision and induces vaginal adenosis.