Our Active Clinical Trials
- The Wingspan™ Stent System with Gateway™ Percutaneous Transluminal Angioplasty (PTA) Balloon Catheter, an FDA-Designated Humanitarian Use Device (HUD) Approved for Human Device Exemption(HDE) (HUD #03-0101; HDE #050001)(STRYKER CORP.)
- Framing Eighteen Coils in Cerebral Aneurysms Trial (FEAT)
- "A prospective, multi-center, double-blind, randomized, placebo-controlled, parallel-group, Phase 3 study to assess the efficacy and safety of clazosentan in preventing clinical deterioration due to delayed cerebral ischemia (DCI), in adult subjects with aneurysmal subarachnoid hemorrhage (aSAH); ID-054-304"
- The Codman Enterprise™ Vascular Reconstruction Device and Delivery System an FDA-Designated Humanitarian Use Device (HUD) Approved under the Humanitarian Use Device Exemption on 08 May 2007, HDE NO. H060001
- EffectiveNess and SAfety of Small ANeurysm COiling trial (NANO)
- Embolization of the Middle Meningeal Artery with ONYX™ Liquid Embolic System In the Treatment of Subacute and Chronic Subdural HEmatoma (EMBOLISE)
- Early Minimally-Invasive Removal of ICH Ruptured Aneurysms Treated with Hydrogel Coils
- Retrospective analysis of patients receiving anticoagulation and antiplatelet therapy in the setting of a neurovascular stenting procedure
- Open-Label Safety Study of Glial Cell Line-Derived Neurotrophic Factor Gene Transfer (AAV2-GDNF) in Parkinson's Disease
- A Phase I/II, Randomized, Double-blind, Sham Control Multiple Ascending Doses of Striatally-Administered rAAV5-miHTT Total Huntingtin Gene (HTT) Lowering Therapy (AMT-130) in Early Manifest Huntington Disease
- A Single-Stage, Adaptive, Open-Label, Dose Escalation Safety Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase (AAV2-hAADC) Administered by MR-Guided Convective Infusion into the Midbrain in Pediatric Patients with AADC Deficiency (AAV2-hAADC)
- A Randomized, Placebo Surgery Controlled, Double-blinded, Multi-center, Phase 2 Clinical Trial, Evaluating the Efficacy and Safety of VY-AADC02 in Advanced Parkinson's Disease with Motor Fluctuations; PD-1105
- Randomized, double-blind, placebo-controlled safety study of glial cell line-derived neurotrophic factor gene transfer (aav2-gdnf) in multiple system atrophy (msa-101 aav2-gdnf): surgical site
- A Phase I Study to Assess the Safety, Tolerability and Preliminary Efficacy of AAV2-BDNF [Adeno-Associated Virus (AAV)-based, Vector-Mediated Delivery of Human Brain Derived Neurotrophic Factor] in Subjects with Early Alzheimer’s Disease and Mild Cognitive Impairment
- A Retrospective Analysis of Outcomes Following Surgical Management of Sinonasal Malignanacies with Skull Base Involvement
- A PROSPECTIVE LONGITUDINAL QUALITY-OF-LIFE STUDY IN PATIENTS UNDERGOING ENDOSCOPIC ENDONASAL SKULL BASE SURGERY
- A Prospective Trial of Oral Urea for the Treatment of Symptomatic Hyponatremia in Patients Presenting After Skull Base Surgery
- Validation of a Novel Patient-Reported Quality of Life Metric “Prolac-10” for Patients Undergoing Medical Therapy for Prolactinoma
- Evolution of a Novel “Frailty Index” To Predict Survival in Patients Receiving Surgery for Brain Metastases: The OHK Score
- VALIDATION OF A PATIENT-REPORTED QUALITY OF LIFE METRIC PROMIS-29, FOR PATIENTS UNDERGOING CRANIOTOMY OR CRANIECTOMY
- ENDONASAL ENDOSCOPIC SURGERY FOR SKULL BASE CHONDROSARCOMAS: RETROSPECTIVE ANALYSIS OF OUTCOMES
- Clinical Outcomes and Tumor Recurrence in Pituitary Apoplexy
- The Clinical Utility of Neuromonitoring in Endoscopic Endonasal Skull Base Surgery
- Pre and Post-Operative Cognitive Status in Patients Undergoing Surgery for Resection of Meningioma associated with the frontal and temporal lobes
- Retrospective Review of Endoscopic Endonasal Surgery for Pituitary Adenomas At the Ohio State University Wexner Medical Center
- Surgical outcomes for tumor resection with expanded endonasal techniques
- Surgical outcomes for transcranial compared to endonasal or combined approaches for olfactory groove meningiomas
- Retrospective Review of Complications Related to Extended Endoscopic Endonasal Skull Base Surgery at The Ohio State University Wexner Medical Center
- Patient-Reported Outcome Measure for Meningiomas study
- Comparative analysis of endoscopic assisted and purely microvascular decompression for posterior fossa cranial nerves. Our experience
- Soft gasket seal - a new closure technique for endoscopic endonasal approaches: a comparative study
- Study to Explore Safety, Tolerability, and Efficacy Signals of DTI
- Proposal for Evaluation of Overlay Real-time video enhancement with Intraoperative Administration of Intravenous Indocyanine Green: optimizing parameters and defining applications in Endoscopic Endonasal Cranial Base Surgery
- Neurosurgical Specimen Collection Protocol in Collaboration with UMMC
- Lumbar Fusion with 3D-Printed Porous Titanium Interbody Cages – A Single-Blinded Randomized Controlled Trial Evaluating Nexxt MatrixxTM Versus PEEK Cages
- Ohio State University TRACK SCI Registry
- General Spinal Arthrodesis Database
- ACDF 3D printed Cage DePuy Synthes
- Assessment of deep brain stimulation on Parkinson’s disease-associated spinal disorders
- The natural history of Parkinson’s disease-associated spinal disorders
- Clinical and Radiological Outcomes of Posterior Cervical Fusion Supplemented with Interfacet Spacers
- Analysis of Pedicle Screw Accuracy to Plan Using Medtronic Mazor Robotic System
- Retrospective analysis of outcomes related to transforaminal lumbar interbody fusions
- Retrospective analysis of pelvic instrumentation
- Clinical and Radiological Outcomes of Posterior Cervical Fusion with Medtronic Infinity Occipitocervical-Upper Thoracic (OCT) System
- Factors associated with proximal junctional kyphosis and failure after long segment thoracolumbar fusions
- Post-operative measurements of cervical spine lordosis and sagittal vertical alignment with varying cervical traction methods: a retrospective analysis.
- Prospective, Randomized, Controlled, Blinded Pivotal Study In Subjects Undergoing A Transforaminal Lumbar Interbody Fusion (TLIF) At One Or Two Levels Using Infuse™ Bone Graft and The Capstone™ Spinal System with Posterior Supplemental Fixation For The Treatment Of Symptomatic Degenerative Disease Of The Lumbosacral Spine
- Factors associated with adjacent segment disease after two-level anterior cervical discectomy and fusion versus two-level anterior cervical disc arthroplasty
- Lumbar Fusion with Micro and Nano-textured Titanium Interbody Cages - A Single-Blinded Randomized Controlled Trial Evaluating Adaptix™ nanoLOCK® Versus PEEK Cages
- Retrospective review of patients with Primary Central Nervous System Lymphoma
- Retrospective review of patients with metastatic disease with seizure disorder
- Retrospective Review and Analysis of Patients with Pseudotumor Cerebri (PTC) Who Require CSF Diversion Systems
- A Retrospective Case Review of Sterotactic Radiosurgery for the Treatment of Meningiomas
- Retrospective Review and Analysis of Adult Patients with Pseudotumor Cerebri (PTC) who Require CSF Diversion Systems
- Management of Idiopathic Intracranial Hypertension (IIH) In Pregnancy
- DBS-Expert: Automated Deep Brain Stimulation Programming Using Functional Mapping Phase II
- A pilot open-label clinical trial evaluating the ExAblate Model 4000 Type-1 focused ultrasound thalamotomy for the prevention of secondary generalization in focal onset epilepsy
- AL-002: Assessment of Safety and Efficacy of ExAblate Blood-Brain Barrier Disruption for the Treatment of Patients with Probable Alzheimer’s Disease
- A feasibility study of in-vivo recordings from a fully-passive and wireless neurosensing system (WiNS) "wireless"
- Predictors of outcomes after DBS and HIFU
- RECLAIM DEEP BRAIN STIMULATION (DBS) THERAPY FOR OBSESSIVE COMPULSIVE DISORDER HDE#H050003
- ACTIVA DYSTONIA DEEP BRAIN STIMULATION (DBS) THERAPY, HDE-H020007
- General DBS database
- Cognitive Effects of Deep Brain Stimulation in Parkinson Disease
- Electrophysiological Correlates of Decision Making
- A Pivotal Randomized Study Assessing Vagus Nerve Stimulation (VNS) During Rehabilitation for Improved Upper Limb Motor Function After Stroke (VNS-REHAB)
- A Pivotal Clinical Trial of the Management of the Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Idiopathic Parkinson’s Disease With Unilateral Lesioning of the Globus Pallidum Using the ExAblate Neuro System
- Functional neuroimaging feedback for Focused Ultrasound Thalamotomy
- ND001 US: Global Registry: ExAblate 4000 transcranial MR guided focused ultrasound (TcMRgFUS) of Neurological disorders
- A Continued Access Study to Evaluate the Effectiveness and Safety of ExAblate Transcranial MRgFUS Thalamotomy Treatment of Medication Refractory Essential Subject
- Microlesion induced changes in network dynamics for prediciton of deep brain stimulation efficacy "asleep"
- Physiological brain atlas development
- Investigating multisensory integration in subcortical structures
- Evaluation of the Infinity Deep Brain Stimulation Electrode Screening Mode Tool (EVIDENT)
- Investigating the cortical correlates of spinal cord stimulation using fMRI
- Investigating mechanisms underlying spinal cord stimulation efficacy using virtual reality and full body illusion
- A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor
- Assessment of Drug Craving and Stress Reactivity Respondes in Patients Receiving Intrathercal Opioid Therapy
- A novel approach to determine ablation status and location to improve long term tremor control after focused ultrasound surgery
- A Feasibility Study to Evaluate the Safety and Effectiveness of Bilateral Exablate Treatment of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson’s Disease (PD)
- Neurosurgical Specimen Collection Protocol