The Aging Biomarkers Core team is actively involved in research projects with departments across The Ohio State University and at outside universities and entities across the country. This keeps us engaged with the latest technology and gives us the experience needed to better understand your own research expectations.
As integral members of a research team, we're able to offer testing suggestions, support and feedback during research design through completion and publication.
Below is a list of recent studies we've supported. This is not an exhaustive list, so if there is a specific medical specialty or research format you'd like to confirm our experience with, please let us know so we can share additional examples.
Example publications
- Rosko AE, Elsaid MI, Woyach J, Islam N, Lepola N, Urrutia J, Christian LM, Presley C, Mims A, Burd CE. Determining the relationship of p16INK4a and additional molecular markers of aging with clinical frailty in hematologic malignancy. J. Cancer Surviv. 2024;18(4): 1168–1178. https://doi.org/10.1007/s11764-024-01591-6
- Madison AA, Burd CE, Andridge R, Wilson SJ, Bailey MT, Belury MA, Spakowicz DJ, Malarkey WB, Kiecolt-Glaser JK. Gut microbiota richness and diversity track with T cell aging in healthy adults. J. Gerontol. A Biol. Sci. Med. Sci. 202479(3): glad276. https://doi.org/10.1093/gerona/glad276
- Fell G, Rosko AE, Abel GA, et al. Peripheral blood CD3+ T-cell gene expression biomarkers correlate with clinical frailty in patients with haematological malignancies. Br. J. HaematHaemat ol. 2022;199(1):100–105. https://doi.org/10.1111/bjh.18336
- Galloway JE, Holderbaum AM, Arya N, et al. Impact of age-related T cell dynamics on the identification of biomarkers predictive of immunotherapy discontinuation: a prospective cohort study. Aging and Cancer. 2020;1(1-4):58–70. https://doi.org/10.1002/aac2.12012
- Burd CE, Peng J, Laskowski BF, et al. Association of epigenetic age and p16INK4a with Markers of T-cell composition in a healthy cohort. J Gerontol. 2020; 75(12):2299–2303. https://doi.org/10.1093/gerona/glaa108
- Lucas F, Pennell M, Huang Y,et al. T Cell transcriptional profiling and immunophenotyping uncover LAG3 as a potential significant target of immune modulation in multiple myeloma. Biol Blood Marrow Transplant, 2020; 26(1): 7–15. https://doi.org/10.1016/j.bbmt.2019.08.009