Consultation

  • Biomarker selection
  • IRB protocol development
  • Project budgeting
  • Study implementation and data interpretation

Sample processing for aging biomarker analyses

  • Peripheral blood processing: cell and plasma isolation
  • DNA and RNA isolation
  • Quality control

Streamlined aging biomarker analyses through established partnerships

  • Epigenetic clocks: Run on the Infinium MethylationEPIC v2.0 BeadChip. Returns: Hannum, Horvath, PhenoAge, GrimAge, DunnedinPACE and more.
  • OSU_Senescence Nanostring panel (p16INK4a): Simultaneous measurement of p16INK4a and 73 other mRNAs indicative of T cell subset, cytokine production and exhaustion (See: Burd et al., J Gerontol A Biol Sci Med Sci. 2020;75(12):2299-2303)
  • Spectral flow cytometry analysis of peripheral blood subsets
  • Serum cytokine profiling and CMV seropositivity