November 2024
Leonard MR, Jones DM, Read KA, Pokhrel S, Tuazon JA, Warren RT, Yount JS, Oestreich KJ. Aiolos promotes CXCR3 expression on TH1 cells via positive regulation of IFNγ/STAT1 signaling. JCI Insight. 2024 Nov 19:e180287. doi: 10.1172/jci.insight.180287. Epub ahead of print. PMID: 39560988.
October 2024
Denz PJ, Speaks S, Kenney AD, Eddy AC, Papa JL, Roettger J, Scace SC, Rubrum A, Hemann EA, Forero A, Webby RJ, Bowman AS, Yount JS. Innate immune control of influenza virus interspecies adaptation via IFITM3. Nat Commun. 2024 Oct 30;15(1):9375. doi: 10.1038/s41467-024-53792-3. PMID: 39477971; PMCID: PMC11525587.
Petersen-Cherubini CL, Murphy SP, Xin M, Liu Y, Deffenbaugh JL, Jahan I, Rau CN, Yang Y, Lovett-Racke AE. Autotaxin in encephalitogenic CD4 T cells as a therapeutic target for multiple sclerosis. Eur J Immunol. 2024Jan;54(1):e2350561. doi: 10.1002/eji.202350561. Epub 2023 Oct 30. PMID: 37850588; PMCID: PMC10843518.
Schwieters A, Ahmer BMM. Identification of new SdiA regulon members of Escherichia coli, Enterobacter cloacae, and Salmonella enterica serovars Typhimurium and Typhi. Microbiol Spectr. 2024 Oct 22:e0192924. doi: 10.1128/spectrum.01929-24. Epub ahead of print. PMID: 39436139.
Chen J, Zhao B, Dong H, Li T, Cheng X, Gong W, Wang J, Zhang J, Xin G, Yu Y, Lei YL, Black JD, Li Z, Wen H. Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway. Elife. 2024 Oct 4;13:RP94849. doi: 10.7554/eLife.94849. PMID: 39365288; PMCID: PMC11452177.
September 2024
Gunasena M, Alles M, Demberg T, Mulhern W, Liyanage NPM. BCG immunization induced KLRG1+ NK cells show memory-like responses to mycobacterial and HIV antigens. Cell Immunol. 2024 Sep-Oct;403-404:104865. doi: 10.1016/j.cellimm.2024.104865. Epub 2024 Sep 2. PMID: 39226746.
Liu Z, Sun L, Li L, Miao EA, Amer AO, Wozniak DJ, Wen H. Pseudomonas aeruginosa Mediates Host Necroptosis through Rhl-Pqs Quorum Sensing Interaction. Immunohorizons. 2024 Sep 1;8(9):721-728. doi:10.4049/immunohorizons.2400012. PMID: 39312394; PMCID: PMC11447673.
July 2024
Deffenbaugh JL, Jung KJ, Murphy SP, Liu Y, Rau CN, Petersen-Cherubini CL, Collins PL, Chung D, Lovett-Racke AE. Novel model of multiple sclerosis induced by EBV-like virus generates a unique B cell population. J Neuroimmunol. 2024 Jul 25;394:578408. doi: 10.1016/j.jneuroim.2024.578408. Epub ahead of print. PMID:39098102.
Gunasena M, Alles M, Wijewantha Y, Mulhern W, Bowman E, Gabriel J, Kettelhut A, Kumar A, Weragalaarachchi K, Kasturiratna D, Horowitz JC, Scrape S, Pannu SR, Liu SL, Vilgelm A, Wijeratne S, Bednash JS, Demberg T, Funderburg NT, Liyanage NPM. Synergy Between NK Cells and Monocytes in Potentiating Cardiovascular Disease Risk in Severe COVID-19. Arterioscler Thromb Vasc Biol. 2024 Jul 11. doi: 10.1161/ATVBAHA.124.321085. Epub ahead of print. PMID: 38989579.
Prislusky MI, Lam JGT, Contreras VR, Ng M, Chamberlain M, Pathak-Sharma S, Fields M, Zhang X, Amer AO, Seveau S. The septin cytoskeleton is required for plasma membrane repair. EMBO Rep. 2024 Jul 5. doi: 10.1038/s44319-024-00195-6. Epub ahead of print. PMID: 38969946.
June 2024
Fowler EA, Farias Amorim C, Mostacada K, Yan A, Amorim Sacramento L, Stanco RA, Hales ED, Varkey A, Zong W, Wu GD, de Oliveira CI, Collins PL, Novais FO. Neutrophil-mediated hypoxia drives pathogenic CD8 T cell responses in cutaneous leishmaniasis. J Clin Invest. 2024 Jun 4:e177992. doi: 10.1172/JCI177992. Epub ahead of print. PMID: 38833303.
May 2024
Alles M, Gunasena M, Zia T, D'Mello A, Bhattarai S, Mulhern W, Terry L, Scherger T, Wijeratne S, Singh S, Wijeratne AJ, Kasturiratna D, Tettelin H, Weyand NJ, Liyanage NPM. Unveiling the immune dynamics of Neisseria persistent oral colonization. Infect Immun. 2024 May 30:e0004824. doi: 10.1128/iai.00048-24. Epub ahead of print. PMID:38814083.
Jerome AD, Sas AR, Wang Y, Hammond LA, Wen J, Atkinson JR, Webb A, Liu T, Segal BM. Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration. Nat Immunol. 2024 Jun;25(6):957-968. doi: 10.1038/s41590-024-01836-7. Epub 2024 May 29. PMID: 38811815.
Solstad AD, Denz PJ, Kenney AD, Mahfooz NS, Speaks S, Gong Q, Robinson RT, Long ME, Forero A, Yount JS, Hemann EA. IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN. JCI Insight. 2024 May 21;9(13):e171830. doi: 10.1172/jci.insight.171830. PMID: 38973611.
Badr A, Daily KP, Eltobgy M, Estfanous S, Tan MH, Chun-Tien Kuo J, Whitham O, Carafice C, Gupta G, Amer HM, Shamseldin MM, Yousif A, Deems NP, Fitzgerald J, Yan P, Webb A, Zhang X, Pietrzak M, Ghoneim HE, Dubey P, Barrientos RM, Lee RJ, Kokiko-Cochran ON, Amer AO. Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease. Brain Behav Immun. 2024 Jul;119:919-944. doi: 10.1016/j.bbi.2024.05.006. Epub 2024 May 7. PMID: 38718909.
April 2024
Li P, Liu Y, Faraone JN, Hsu CC, Chamblee M, Zheng Y-M, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Liu S-L. Distinct patterns of SARS-CoV-2 BA.2.87.1 and JN.1 variants in immune evasion, antigenicity, and cell-cell fusion. mBio. 2024 Apr 9:e0075124. doi: 10.1128/mbio.00751-24. PMID: 38591890.
Rau CN, Severin ME, Lee PW, Deffenbaugh JL, Liu Y, Murphy SP, Petersen-Cherubini CL, Lovett-Racke AE. MicroRNAs targeting TGF-β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function. Eur J Immunol. 2024 Apr 18:e2350548. doi: 10.1002/eji.202350548. PMID: 38634287.
Read KA, Amici SA, Farsi S, Cutcliffe M, Lee B, Lio CJ, Wu HJ, Guerau‐de‐Arellano M, Oestreich KJ. PRMT5 Promotes T follicular helper Cell Differentiation and Germinal Center Responses during Influenza Virus Infection. J Immunol. 2024 Mar 4:ji2300270. doi: 10.4049/jimmunol.2300270. PMID: 38436421.
Speaks S, McFadden MI, Zani A, Solstad A, Leumi S, Roettger JE, Kenney AD, Bone H, Zhang L, Denz PJ, Eddy AC, Amer AO, Robinson RT, Cai C, Ma J, Hemann EA, Forero A, Yount JS. Gasdermin D promotes influenza virus‐ induced mortality through neutrophil amplification of inflammation. Nat Commun. 2024 Mar 29;15(1):2751. doi: 10.1038/s41467‐024‐47067‐0. PMID: 38553499; PMCID: PMC10980740.
February 2024
Bitting RL, Tooze JA, Goodman M, Vile DC, Brown JM, Thomas CY, Neve M, Kooshki M, Addo S, Triozzi PL, Dubey P. Low-dose Paclitaxel with Pembrolizumab Enhances Clinical and Immunologic Responses in Platinum-refractory Urothelial Carcinoma. Cancer Res Commun. 2024 Feb 26;4(2):530-539. doi: 10.1158/2767-9764.CRC-23-0436. PMID: 38345536; PMCID: PMC10896069.
Jones DM, Tuazon JA, Read KA, Leonard MR, Pokhrel S, Sreekumar BK, Warren RT, Yount JS, Collins PL, Oestreich KJ. Cytotoxic Programming of CD4+ T Cells Is Regulated by Opposing Actions of the Related Transcription Factors Eos and Aiolos. J Immunol. 2024 Feb 16:ji2300748. doi: 10.4049/jimmunol.2300748. PMID: 38363226.
Li J, Ma A, Zhang R, Chen Y, Bolyard C, Zhao B, Wang C, Pich T, Li W, Sun N, Ma Q, Wen H, Clinton SK, Carson WE 3rd, Li Z, Xin G. Targeting metabolic sensing switch GPR84 on macrophages for cancer immunotherapy. Cancer Immunol Immunother. 2024 Feb 13;73(3):52. doi: 10.1007/s00262-023-03603-3. PMID: 38349405; PMCID: PMC10864225.
Qu P, Xu K, Faraone JN, Goodarzi N, Zheng YM, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Gumina RJ, Liu SL. Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants. Cell. 2024 Feb 1;187(3):585-595.e6. doi: 10.1016/j.cell.2023.12.026. Epub 2024 Jan 8. PMID: 38194968; PMCID: PMC10872432.
Stoodley P, Toelke N, Schwermer C, de Beer D. Bioenergetics of simultaneous oxygen and nitrate respiration and nitric oxide production in a Pseudomonas aeruginosa agar colony biofilm. Biofilm. 2024 Feb 10;7:100181. doi: 10.1016/j.bioflm.2024.100181. PMID: 38425549; PMCID: PMC10902143.
January 2024
Akkaya M, Al Souz J, Williams D, Kamdar R, Kamenyeva O, Kabat J, Shevach E, Akkaya B. Illuminating T cell-dendritic cell interactions in vivo by FlAsHing antigens. Elife. 2024 Jan 18;12:RP91809. doi: 10.7554/eLife.91809. PMID: 38236633.
Liu Y, McQuillen EA, Rana PSJB, Gloag ES, Parsek MR, Wozniak DJ. A bacterial pigment provides cross-species protection from H2O2- and neutrophil-mediated killing. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2312334121. doi: 10.1073/pnas.2312334121. Epub 2024 Jan 3. PMID: 38170744; PMCID: PMC10786307.
Petersen-Cherubini CL, Liu Y, Deffenbaugh JL, Murphy SP, Xin M, Rau CN, Yang Y, Lovett-Racke AE. Dysregulated autotaxin expression by T cells in multiple sclerosis. J Neuroimmunol. 2024 Jan 3;387:578282. doi: 10.1016/j.jneuroim.2023.578282. PMID: 38183947.