Project Title: The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy in Patients with Moderate Risk of Postoperative Infection
IRB Number: 2017H0055
PI: Knudsen
Co-I: Sourial
Description: Currently, the field of Urology does not have a standard pre-operative antibiotic treatment for patients about to receive an operative stone treatment called Percutaneous Nephrolithotomy (PCNL). This is a multi-institutional trial, with participating sites spanning the US and Canada, that will assist us in finding out what the best course of preoperative antibiotics are for patients undergoing this procedure.
Project Title: Prospective Trial of a Reusable Digital Flexible Ureteroscope vs a Single-Use Flexible Ureteroscope in the Treatment of Urolithiasis: An EDGE Consortium Clinical Trial
IRB Number: 2017H0118
PI: Knudsen
Co-I: Sourial
Description: With technology evolving rapidly and constantly, it is up to us to ensure we are using the best products possible for our patients! This multi-institutional trial is comparing the use of a single-use flexible ureteroscope and a reusable ureteroscope during stone treatment. Both scopes are FDA approved and currently used throughout the Wexner Medical Center and The James.
Project Title: A Prospective Randomized Multicenter Trial Comparing Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi
IRB Number: 2018X0078
PI: Sourial
Co-I: Knudsen
Description: With technology evolving rapidly and constantly, it is up to us to ensure we are using the best products possible for our patients! This multi-institutional trial is comparing the use of two intracorporeal lithotripters for stone treatment.
Project Title: M16-100: Testosterone Replacement therapy for Assessment of long-term Vascular Events and efficacy ResponSE in hypogonadal men (TRAVERSE) Study
IRB Number: 2018W0242
PI: Jenkins
Co-I: Shipp
Description: This is a multi-site clinical trial investigating Testosterone Replacement Therapy use of Androgel on Hypogonadal (low testosterone levels) men with or at risk for cardiovascular disease.
Project Title: A Multi-Center Study of Pelvic Fracture Urethral Injury
IRB Number: 2018H0502
PI: Baradaran
Description: This is a multi-institutional clinical trial comparing the practice of early urethral realignment and urinary diversion with a suprapubic tube with a planned delayed urethroplasty. Both forms of treatment are currently considered “standard of care” treatment for urethral injuries, but this trial aims to determine if one has better outcomes than the other.
