Ohio State Navbar

Sign In

Dissertation Defense Archives

Spring 2019

Luxi Chen

Advisor: Michael Caligiuri & Aharon Freud

“Human Innate Lymphoid Cell Biology and Development”​

Alecia Blaszczack

Autumn 2018

Shaneice Mitchell

Advisors: John Byrd and Rosa Lapalombella

"Nicotinamide phosphoribosyltransferase as a therapeutic target in AML"​

Lindsay Webb​

webb.jpgAdvisor: Mireia Guerau-de-Arellano
 

Rachael Hardison

Rachael HardisonAdvisors: Kevin Mason and Sheryl Justice


 

 


 

Summer 2018

Samantha Ohmer

Megan20Duggan.jpgAdvisor: Christopher Walker


 

 
 

Spring 2018

Kelly Regan-Fendt

Zachary Hing

Megan20Duggan.jpgAdvisors: John Byrd and Rosa Lapalombella
 

 

 

 

 

 

Autumn 2017

Summer 2017

Spring 2017

  Linan Wang

Advisor: Michael Freitas


Vivek Chowdhary

David Clever

Megan20Duggan.jpgAdvisor: Larry Schlesinger
 
T Cell-Intrinsic Oxygen Sensing Regulates Pulmonary Immunity

Megan Duggan

Megan20Duggan.jpgAdvisor: William E. Carson III
 

Priscilla Do

Advisor: John Byrd
 

Stephen Bergin

Advisor: Michael Caligiuri
 

Tatevik Broutian

Advisor: Maura L. Gillison
 

Andrew Stiff

Advisor: William E. Carson III

Autumn 2016

Nicholas Chesarino

Chesarino_Nicholas.jpgAdvisor: Jacob Yount

Sara Koenig

Advisor: Vidu Garg
 

Tierra Ware

 
Advisors: Joanna Groden and Clay Marsh

"Epigenetic and Pten regulation of Longevity Pathways as it Relates to Idiopathic Pulmonary Fibrosis and Organismal Aging"

         

Emily McWilliams

EmilyMcwilliamsPic.jpg Advisors: John Byrd and Natarajan Muthusamy

"Restoring Innate NK-cell Immunity with Antibody Therapeutics in CLL B-Cell Malignancy"

         

Jeremy Baeten

 JeremyBaeten.jpgAdvisor: Brenda Lilly

"The Roles of the Notch2 and Notch3 Receptors in Vascular Smooth Muscle Cells"

         

Cynthia Canan

CynthiaWupic.jpg Advisor: Joanne Turner  

Alaina Martinez

  Advisor: Joanna Groden and Jeffrey Parvin    


 

William Hankey

  

Hankey-William.jpgAdvisor: Joanna Groden 

Chromatin-associated APC tumor suppressor protein antagonizes canonical WNT repression of the MALL gene

        

Katherine Hartmann

KateHartmannPortraitresize(1).jpgAdvisor: Sadee Wolfgang


 

 

Summer 2016

Cecelia Miller

  miller.jpgAdvisor: John Byrd

"Discovery and Functional Interrogation of Biomarkers Related to Therapeutic Response in Chronic Lymphocytic Leukemia "
                                  

Spring 2016

David Clever

Megan20Duggan.jpgAdvisor: Larry Schlesinger

T Cell-Intrinsic Oxygen Sensing Regulates Pulmonary Immunity
Advisor: John Byrd


 
 

Ashley Jackson

Advisor: Kirk Mchugh

Michael Makara

download.jpegAdvisor: Peter Mohler

"Molecular physiology of ankyrin-G in the heart: Critical regulator of excitability and cellular architecture" 

 

 

Elizabeth McMichael

McMichael_Elizabeth.jpgAdvisor: William Carson
 

 

 

Komal Rambani

Advisor: Gustavo Leone

"A genome wide screen in C. elegans identifies cell non-autonomous suppressors of oncogenic Ras mediated over-proliferation"

 

Steven Scoville

scoville.jpgAdvisor: Michael Caligiuri


 

Michael Trimarchi

Advisor: Joanna Groden


Parker Woods

ParkerWoodspic.jpgAdvisor: Ian Davis


 

 

 

 

Autumn 2015

Kyle Caution

Kyle-Caution.jpg   
Advisor: Amal Amer 

Jacqueline Corry


 

 

 

Sara Johnson

Mary Severin

mary severin.jpg
Advisor: Amy Lovett-Racke

 

 


Catherine Waters

CatherineWatersphoto.jpg
Advisor: Kay Huebner


 

Summer 2015

Advisor: W. James Waldman


 

Carolyn Paisie

 
Advisor: Kay Huebner


 

 

Spring 2015

Advisor: Ramesh Ganju
 

 
AAEAAQAAAAAAAAKAAAAAJDUzMjYxMDlkLWM3ZTAtNDAzOC1hNjIwLTU4ZmQxNTg0MzQ0Ng.jpgAdvisor: Wolfgang Sadee


 
helongzhaopic.jpgAdvisor: Ramesh Ganju
 

 

 

Autumn 2014 

Nathan Dissinger

Dissinger-Nathan.jpgAdvisor: Patrick Green 
 

 

 

 

 


 

Adam Rauckhorst 

Advisor: Douglas Pfeiffer 

Estevan A. Santana 

Santana-Estevan.jpgAdvisor: Robert S. Munson 


 

 

Elizabeth Stofko-Barrie 

Beth-Stofko.jpgAdvisor: Wolfgang Sadee


 

 

Summer 2014 

Spring 2014

Julie Ann Dougherty

Julie-Dougherty-2.jpgAdvisor: Daniel R. Schoenberg


 

 

Nima Milani-Nejad 

Nimamilani.jpgAdvisor: Paul M.L. Janssen 


 

Benjamin R. Nixon 

Nixon-Benjamin.jpgAdvisor: Brandon J. Biesiadecki


 

James Perry

Advisor: Arnab Chakravarti 
 


 

 

Autumn 2013

Chelsea Bolyard

chelseabolyard.jpgAdvisor: Balveen Kaur


 

 

Heather Costello

Heather-Costello.jpgAdvisor: Mark Peeples

"The N500 Glycan of the Respiratory Syncytial Virus F Protein is Required for Fusion, but not for Stabilization or Triggering of the Protein"


 

Devyn Gillette

PhotoNotAvailable.jpgAdvisor: Susheela Tridandpani

 

 

Sean Harshman

Harshman-Sean.jpgAdvisor: Michael A. Freitas

"Characterization of Histone H1 and Extracellular Vesicles by Mass Spectrometry"


 

Kelly Johnson 

kelly-nye.jpgAdvisor: Traci Wilgus 


 

 

Suman Kanji 

Kanji Suman.pngAdvisors: Sujit Basu and Hiranmoy Das


 

Joanna Marshall

Joanna-Marshall.jpgAdvisor: John S. Gunn


 

 

Joseph Ostler

josephostler.jpgAdvisor: Muthu Periasamy 
 

 

Caroline Padro

Caroline-Padro.jpgAdvisor: Virginia M. Sanders


 

Christopher Penton 

chrispenton.jpgAdvisor: Federica Montanaro
 

 

Brenda Reader

BrendaReaderresized.jpgAdvisor: John F. Sheridan
 

 

Dawn Walker

Dawn-Walker-2.jpgAdvisor: Mark E. Drew


 

William Willis

Advisor: Art Strauch 
 

Summer 2013

Edward Briercheck

Advisor: Michael Caliguiri


"Elucidation of the Mechanism by which Phosphatase and Tensin Homologue Deleted on Chromosome Ten (PTEN) Regulates Natural Killer Cell Function"


 

Joshua Oakes

Advisor: Danilo Perrotti


 

Ira Racoma

Advisor: Altaf Wani


“Targeting Glioblastoma Survival Signaling: A Novel Mechanism of Action of Thymoquinone”


 

Nicholas Zorko

Advisor: Michael Caliguiri


“The role of the mixed lineage leukemia partial tandem duplication in acute myeloid leukemogenesis”


 

Spring 2013

Erin Burns

Erin BurnsAdvisor: Tatiana Oberyzyn


"Men and Women are Not Just From Different Planets: The Role of Sex-Based Differences in the Prevention of Non-Melamona Skin Cancer"


 

Erin Frey

Erin FreyAdvisor: Candice Askwith


"Acid-Sensing Ion Channels: Targets for Neuropeptide Modulation and Neuronal Damage"


 

Alena Cristina Jaime-Ramirez

Alena Cristina Jaime-RamirezAdvisor: Bill Carson


"The NK Cell-mediated Anti-tumor Effects of a Folate-conjugated Immunoglobulin are Enhanced by Cytokines”


 

Samantha McCarty

Reeva AggarwalAdvisor: Matthew D. Ringel


"A Novel Braf Signaling Cascade through p-21 Activated Kinases Regulates Thyroid Cancer Cell Motility"


 

Pierpaolo Peruzzi

Pierpaolo PeruzziAdvisor: E. Antonio Chiocca and Balveen Kaur


"MiR-128 Controls the Activity of Polycomb Repressor Complexes 1 and 2 in Neural Stem Cells: Implications of its Loss in Gliomagensis"


 


Joshua C. Saldivar

Reeva AggarwalAdvisor: Kay Huebner


"The Origin of Genome Instability in Cancer: Role of the Fragile Site Gene Product Fhit"


 

Autumn 2012

Reeva Aggarwal

Reeva AggarwalAdvisor: Hiranmoy Das


"Mechanisms of Human CD34+ Stem Cell-Mediated Regulation of Osteoporosis in a Preclinical Model."


 

Houda Alachkar

Reeva AggarwalAdvisor: Guido Marcucci


“SPARC Contributes to Leukemia Growth and Aggressive Disease in Acute Myeloid Leukemia (AML)”


 

Rodney D. Britt Jr.

Rodney BrittAdvisor: Lynette Rogers


"The Role of Cyclooxygenase-2 in Newborn Hyperoxic Lung Injury."


 

April Renee Sandy Gocha

April Renee Sandy GochaAdvisor: Joanna Groden


"Mechanisms of alternative telomere elongation in human cancer cells ."


 


 

Jill Green

Jill GreenAdvisor: Kirk Mykytyn


"Characterization of Neuronal Primary Cilia in Cellular Homeostasis and Disease."


 

 

Sean Little

Sean LittleAdvisor: Jonathan P. Davis


"The Role of Troponin C in the Heart."


 


 

Chris Lucas

Chris LucasAdvisor: Virginia M. Sanders


"Prohibitins and the Cytoplasmic Domain of CD86 Cooperate to Mediate CD86 Signaling in B Lymphocytes."


 


Ananth Narayanan

Ananth NarayananAdvisor: Petra Schmalbrock


"Pharmacological Modulation of Functional Connectivity in Neuropsychological Disorders."


 

Steve Roof

Reeva AggarwalAdvisor: Mark T. Ziolo


“Neuronal Nitric Oxide Synthase Signaling Contributes to the Beneficial Cardiac Effects of Exercise”



 

Nikki Seagraves

   Advisor: Kim McBride

Jessica Suboticki

    Advisor: Paul Janssen 

Summer 2012

Joshua Cyktor

Joshua CyktorAdvisor: Joanne Turner


"Immune Correlates of Resistance and Susceptibility to Tuberculosis."


 

Xun Lan

Xun LanAdvisor: Victor Jin


"Uncover Transcription Factor Networks by Integrating One Dimensional 'Omics and Three Dimensional Chromatin Structure."



 

Richard Price

Richard PriceAdvisor: E. Antonio C​hiocca


"The Role of Cytomegalovirus in Glioblastoma and Rhabdomyosarcoma."


 



Spring 2012

Adam Bevan

Adam BevanAdvisor: Brian K. Kaspar


"AAV-based approaches for modeling and treating spinal muscular atrophy."


 


 

Patrick Grierson

Patrick GriersonAdvisor: Joanna Groden


"The BLM helicase facilitates RNA polymerase I-mediated ribosomal RNA transcription."


 

Kaylan Haizlip

Advisor: Paul Janssen


“Manipulations and Alterations of the Force-Frequency Response in Isolated Cardiac Muscle”


 

Alison Lyon

Alison LyonAdvisor: Christine E. Beattie


"Generation and Analysis of Motor Neuron Disease Models in Zebrafish."


 


 

Carolyn Marion

Carolyn MarionAdvisor: Samantha King


"Modification and Utilization of Carbohydrates by Streptococcus pneumoniae."


 

Susan McClory

Susan McCloryAdvisor: Michael Caligiuri


"Extrathymic T cell development in the human tonsil."


 

Sarwish Rafiq

Sarwish RafiqAdvisor: John C. Byrd


"Evaluation of Antibody-based Therapeutics for B cell Malignancies."


 


 

Levy Reyes

Levy Austin ReyesAdvisor: Jay L. Zweier


"New Mechanisms for Endothelial Nitric Oxide Synthase Dysfunction in the Isolated Rat Heart."


 


 

Kenny Roman

Kenny RomanAdvisor: Robert Stephens


"GLT-1 Over-Expression Attenuates Bladder and Colonic Nociception By Either Pharmacological or Gene Therapy Approach"


 


 

Neha Singhal

Neha SinghalAdvisor: Paul T. Martin


"Distinct roles of synaptic GalNAc transferases, Galgt1 and Galgt2, in muscle biology."


 

Sarah Stevens

Sarah StevensAdvisor: Loren E. Wold


"Calcium and Cancer: Implications for Cardiovascular Function and Disease."


 

Fatemeh Talebian

Fatemeh TalebianAdvisor: Xue-Feng Bai


CD200-CD200R Interaction in Tumor Immunity

Winter 2012

Rebecca Allen

Rebecca AllenAdvisor: John Sheridan


"Macrophage microbicidal activity is enhanced by stressor-exposure."




Bryan Anthony

Bryan AnthonyAdvisor: Gregg Hadley


"The Role of CD103 Expression in Promoting Intestinal Graft Versus Host Disease."


 

Kristen Smith

Kristen SmithAdvisor: Caroline Whitacre


"MicroRNAs in multiple sclerosis: a study of the effects on T cell trafficking and effector function."


 


 

Autumn 2011

Huizi Chen

Huizi ChenAdvisor: Gustavo Leone


"Atypical E2Fs link mammalian endocycle control to cancer."


 

Gina Mavrikis Cox

Gina CoxAdvisor: Caroline C. Whitacre


"Macrophage migration inhibitory factor: a study of the effects on the central nervous system microenvironment autoimmune encephalomyelitis."



Dennis Horvath

Dennis HorvathAdvisor: Sheryl Justice


"The Impact of Phagocyte-UPEC Interactions Upon Pathogenesis of Urinary Tract Infections."


 

Summer 2011

Besma Abbaoui

Besma AbbaouismallerAdvisor: Steven Clinton


“Broccoli Isothiocyanates as Chemopreventive Agents and Epigenetic Modulators of Bladder Cancer”

Dustin Donnelly

Dustin DonnellyAdvisor: Denis Guttridge


“Tailoring the heterogeneous macrophage response to spinal cord injury towards neuroprotection"


 

Sara Fischer

Sara FischerAdvisor: Clay Marsh


“Electrospun Nanofiber Scaffolds as a Model of the Lung Microenvironment in Pulmonary Fibrosis”


 

Bethany Mundy

Bethany MundyAdvisor: William Carson


“Myeloid-Derived Suppressor Cells in Tumor Immunology”


 

Alan Smith

Alan SmithAdvisor: Amy Lovett-Racke​


“IL-23 Receptor Expression and Effects of Signaling on T Cell Encephalitogenicity”


 

Georgia Triantafillou

Georgia TriantafillouAdvisor: John Byrd


"CD74 Targeted Nanoparticles as Dexamethasone Delivery System for B lymphoid Malignancies"

Jessica Williams

Jessica WilliamsAdvisor: Caroline Whitacre


“Pregnancy-associated Effects on Immune Modulation and Neuroprotection in a Model of Multiple Sclerosis: Role of T Cells and Serum Exosomes”


 

Dan Xu

Dan XuAdvisor: Christopher Walker


“Cellular Immunity in Adeno-Associated Virus Mediated Gene Therapy”


 

Spring 2011.

Jordan Jensen

Jordan JensenAdvisor: Jeffrey Kuret

"Development of Tau-Selective Imaging Agents for Improved Diagnosis of Alzheimer’s Disease and Other Tauopathies"


 

Olga Malykhina

Olga MalykhinaAdvisor: Mark Peeples

Christopher J. Traynham

Christopher TraynhamAdvisor: Mark T. Ziolo

"Effects of Neuronal Nitric Oxide Synthase Signaling on Myocyte Contractile Function"


 

Winter 2011

Shante Williams

Advisors: Sean Lawler and Antonio Chiocca

"The Role of Glycogen Synthase Kinase3 Inhibitors in Brain Tumor Migration and Invasion"


 

Autumn 2010

Stephanie Cush

Advisor: Emilio Flano

"Generation and Function of CD8 T Cell Memory to γ-Herpesviral Infection"


 

Chad Groer

Advisors: Laura Bohn and Wolfgang Sadee

"Agonist-Selective Regulation of the Mu Opioid Receptor by βarrestins"

Mark Hanke

Advisor: John Sheridan

"Sympathetic Nervous System Mediated Alterations in the Immunological and Behavioral Effects of Social Defeat"


 

Sarah May Herman

Advisor: John Byrd

"Manipulation of Kinase Signaling in Chronic Lymphocytic Leukemia: The effect on Disease state"


 

Anna Kwilas

Advisor: Mark Peeples


"Respiratory Syncytial Virus Based Vectors for the Treatment of Cystic Fibrosis"

Robert Moyer

Advisor: Wolfgang Sadee


"Exploration of Functional Genetic Variants in Candidate Genes for Psychiatric Disorders"


 


 

Amber Nagy

Advisor: James Waldman


"Characterization and Interaction of Nanoparticles in Biological Systems"


 

Susan Richards

Advisor: John Gunn


"PhoPQ- and PmrAB-mediated LPS Modification and Cationic Antimicrobial Peptide Resistance in Salmonella enterica Serovars Typhimurium and Typhi"


 

Summer 2010

Sasha Beyer

Advisor: Sissy Jhiang


"Modulation of Cell Surface Sodium Iodide Symporter Expression and Activity in Breast Cancer"


 

Jordan Gladman

Advisor: Dawn Chandler


"Understanding RNA Splicing to Fight Spinal Muscular Atrophy"


 


 

Spring 2010

Jessica L. Buescher

Advisor: Christopher Phiel


"Structure-Function Analysis of GSK-3 Isoforms"


 


Melinda C.C. Dunn

Advisor: James Waldman


"Inhibition of Respiratory Syncytial Virus in Vitro and In Vivo by the Experimental Immunosuppressive Agent Leflunomide"


 

Amanda M. Haidet

Advisor: Brian Kaspar


"Gene Therapy for Neuromuscular Disorders"


 

Sanjida Saklayen

Advisor: Howard Gu


"Effects of Propranolol on Cognition and Eye Contact in Autism Spectrum Disorders (ASD)"

Winter 2010

Victoria Best

Advisor: Christopher Walker


"Ongoing Cellular Responses to Transgene Products Encoded by Recombinant Adeno-Associated Virus (RAAV)"


 

Troy Cline

Advisor: Joan Durbin


"Innate Immune Mechanisms of Controlling Respiratory Virus Infection"


 

Jason M. Dahlman

Advisor: Dennis Guttridge


"Investigating the Molecular Mechanisms Involved in Skeletal Muscle Development: NF-kB and Skeletal Myogenesis"



 

Amy Dworkin

Advisor: Amanda Toland


"Environmental and Genetic Contributions of Susceptibility to Cutaneous Squamous Cell Carcinoma"


 

Ene Raig Fairchild

Advisor: William Carson


"Differential Expression of MicroRNAs in Melanoma"


 

Sohee Kim

Advisor: Jeff Kuret


"Computational modeling in Alzheimer's disease"

Kathryn J. Kitzmiller

Advisor: C. Yung Yu


"Variation of Complement Factor H and Mannan Binding Lectin in Systemic and Vascular Immune-Mediated Diseases"


 

Benjamin A.T. Rodriguez

Advisor: Tim Huang


"Estrogen represses target genes through epigenetic modification of proximal and distal elements"

Chris Woldford

Advisor: Tsonwin Hai


"The Roles of ATF3, an Adaptive Response gene, in Cancer Development and Metastasis"


 

Autumn 2009

Corey Clay

 Advisor: Larry Schlesinger

Chalonda Handy

 Advisor: Brian Kaspar 

Anuradha Kalyanasundaram

 Advisor: Muthu Periasamy

Holly Moose

 Advisor: Heithem El-Hodiri

Krithika Selvarajan

Advisor: Sampath Parthasarathy


"Adherent and Non Adherent Macrophages in Cell Survival and Death"


 


 

Inimary Toby

Advisor: Leif Nelin


"Activation of Epidermal Growth Factor Receptor and Stimulation of Arginase in Pulmonary Hypertension"


 

Summer 2009

Anna Eiring

 Advisor: Danilo Perrotti

Christopher I. Karanfilov

Advisor: Alan Litsky


"Ion Implantation of Ultra High Molecular Weight Polyethylene"

Preeyal Kotadiya

Advisor: Beth Lee

Jessica Suboticki

Advisor: Paul Janssen 

Jennifer J. Stanke

Advisor: Andy Fischer


"Beyond Neuronal Replacement: Embryonic Retinal Cells Protect Mature Retinal Neurons"

 

Jessica Suboticki

Advisor: Paul Janssen 

Spring 2009

Brian L. Bell

Advisor: John Gunn


"Regulation of Virulence Gene Transcripts by the Francisella Orphan Response Regulator PmrA"

Amanda Michelle Beltramini

Advisor: Vijay Pancholi


"Eukaryotic-like serine/threonine kinase signaling in Staphylococcus aureus"


 

Edward Chang

Advisor: Jeff Kuret


"Role of Tau Protein in Neurodegenerative Disorders"

Robert Crawford

Advisor: John Gunn


"Chronic Carriage of Salmonella: Biofilms and Gallstones"


 

Jennifer M. Curry

Advisor: Clay Marsh


"Microenvironment Effects on Angiogenesis"

Nitisha Hiranandan

Advisor: Paul Janssen


"Imapact of Reperfusion Injury on Heart"

Aaron Kithcart

Advisor: Caroline Whitacre


"Macrophage Migration Inhibitory Factor: A Key Mediator of Inflammatory Disease"

Mark J. Kohr

Advisor: Mark Ziolo


"Modulation of Cardiac Contraction by Reactive Nitrogen Species"


 


Jaclyn Walisa McAlees

Advisor: Virginia Sanders


"Allergic asthma and the regulation of IgE production by B lymphocytes"


 

Erin K. Rottinghaus

Advisor: Joanne Turner


"Pulmonary Innate Immune Mechanisms in Old Mice"



 

Winter 2009

Kristin M. Ackerman

Advisor: Robert Boyd


"Zebrafish Neuronal Nicotinic Acetylcholine Receptors:Cloning, Expression, and Functional Analysis"

F Jason Duncan

Advisor: Tatiana Oberyszyn


"THE EFFECTS OF BLACK RASPBERRY EXTRACT ON UVB-INDUCED INFLAMMATION AND CARCINOGENESIS"


 

Kristen M. Raehal M.A.

Advisor: Laura Bohn


"Opioid-Induced Side Effects in Beta-Arrestin2 and G Protein Coupled Receptor Kinase Knockout Mice"


Yee Wu

  Advisor: Chack Yung

Autumn 2008

James M. Pauff

AAEAAQAAAAAAAAltAAAAJDY0ODdlZmVkLWI2NzAtNDNlMC1hODc0LThmYmIyZDJiMTk1NA.jpgAdvisor: Virginia Sanders


"Structure-Function Studies of Xanthine Oxidoreductase"


 

Brian C. Wulff

Advisor: Tatiana Oberyszyn


"Effects of Therapeutic Immunosuppressants on UVB Induced Inflammation and Skin Carcinogenesis in a Murine Model" ​​​​​​​​​​​​​​​​​